End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 21, 2011, Pages 8826-8831

  Leterrier, Christophe ^a,b   Vacher, Hélène ^a,b   Fache, Marie Pierre ^a,b   D'Ortoli, Stéphanie Angles ^a,b   Castets, Francis ^a,b   Autillo Touat, Amapola ^a,b   Dargent, Bénédicte ^a,b  

^a INSERM   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; ANKYRIN G; BINDING PROTEIN; PROTEIN EB3; PROTEINS EB1; UNCLASSIFIED DRUG;

ARTICLE; AXON INITIAL SEGMENT; CELL COMPARTMENTALIZATION; CELL MATURATION; CELL POLARITY; DENDRITE; HYDROPHOBICITY; MICROTUBULE; NERVE CELL; NERVE FIBER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; UPREGULATION;

ANIMALS; ANKYRINS; AXONS; CELL POLARITY; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NEURONS; PROTEIN BINDING; RATS; RATS, WISTAR;

EID: 79957673694     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018671108     Document Type: Article

References (29)

1. Kapitein LC, Hoogenraad CC (2011) Which way to go? Cytoskeletal organization and polarized transport in neurons. Mol Cell Neurosci 46:9-20.
2. Clark BD, Goldberg EM, Rudy B (2009) Electrogenic tuning of the axon initial segment. Neuroscientist 15:651-668.
3. Rasband MN (2010) The axon initial segment and the maintenance of neuronal polarity. Nat Rev Neurosci 11:552-562.
4. Brachet A, et al. (2010) Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier. J Cell Biol 191:383-395.
5. Bréchet A, et al. (2008) Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G. J Cell Biol 183:1101-1114.
6. Garrido JJ, et al. (2003) A targeting motif involved in sodium channel clustering at the axonal initial segment. Science 300:2091-2094.
7. Kole MHP, et al. (2008) Action potential generation requires a high sodium channel density in the axon initial segment. Nat Neurosci 11:178-186. (Pubitemid 351170500)
8. Winckler B, Forscher P, Mellman I (1999) A diffusion barrier maintains distribution of membrane proteins in polarized neurons. Nature 397:698-701.
9. Nakada C, et al. (2003) Accumulation of anchored proteins forms membrane diffusion barriers during neuronal polarization. Nat Cell Biol 5:626-632. (Pubitemid 36818084)
10. Song A-H, et al. (2009) A selective filter for cytoplasmic transport at the axon initial segment. Cell 136:1148-1160.
11. Hedstrom KL, Ogawa Y, Rasband MN (2008) AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity. J Cell Biol 183:635-640.
12. Sobotzik J-M, et al. (2009) Ankyrin G is required to maintain axo-dendritic polarity in vivo. Proc Natl Acad Sci USA 106:17564-17569.
13. Akhmanova A, Steinmetz MO (2008) Tracking the ends: A dynamic protein network controls the fate of microtubule tips. Nat Rev Mol Cell Biol 9:309-322. (Pubitemid 351430849)
14. Vacher H, et al. (2011) Cdk-mediated phosphorylation of the Kvbeta2 auxiliary subunit regulates Kv1 channel axonal targeting. J Cell Biol 192:813-824.
15. Gu C, et al. (2006) The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron 52:803-816. (Pubitemid 44828445)
16. Geraldo S, Khanzada UK, Parsons M, Chilton JK, Gordon-Weeks PR (2008) Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis. Nat Cell Biol 10:1181-1189.
17. Jaworski J, et al. (2009) Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron 61:85-100.
18. Stepanova T, et al. (2003) Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J Neurosci 23:2655-2664. (Pubitemid 36418600)
19. Boiko T, et al. (2007) Ankyrin-dependent and -independent mechanisms orchestrate axonal compartmentalization of L1 family members neurofascin and L1/neuron-glia cell adhesion molecule. J Neurosci 27:590-603. (Pubitemid 46143763)
20. Bu W, Su LK (2001) Regulation of microtubule assembly by human EB1 family proteins. Oncogene 20:3185-3192. (Pubitemid 32553671)
21. Akhmanova A, Steinmetz MO (2010) Microtubule +TIPs at a glance. J Cell Sci 123:3415-3419.
22. Honnappa S, et al. (2009) An EB1-binding motif acts as a microtubule tip localization signal. Cell 138:366-376.
23. Komarova Y, et al. (2005) EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol Biol Cell 16:5334-5345. (Pubitemid 41566843)
24. Hedstrom KL, et al. (2007) Neurofascin assembles a specialized extracellular matrix at the axon initial segment. J Cell Biol 178:875-886. (Pubitemid 47347370)
25. Nakata T, Hirokawa N (2003) Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head. J Cell Biol 162:1045-1055. (Pubitemid 37174187)
26. Konishi Y, Setou M (2009) Tubulin tyrosination navigates the kinesin-1 motor domain to axons. Nat Neurosci 12:559-567.
27. Stone MC, Nguyen MM, Tao J, Allender DL, Rolls MM (2010) Global up-regulation of microtubule dynamics and polarity reversal during regeneration of an axon from a dendrite. Mol Biol Cell 21:767-777.
28. Bennett V, Healy J (2009) Membrane domains based on ankyrin and spectrin associated with cell-cell interactions. Cold Spring Harb Perspect Biol 1:a003012.
29. Karlsson R, Katsamba PS, Nordin H, Pol E, Myszka DG (2006) Analyzing a kinetic titration series using affinity biosensors. Anal Biochem 349:136-147. (Pubitemid 43129567)