Identification of the offspring of vegfr2-luc transgenic mouse

Chinese Journal of Lung Cancer

Volumn 14, Issue 5, 2011, Pages 391-395

  Wang, Weiqiang ^a   Liu, Hongyu ^a   Song, Zhitao ^a   Wang, Yuli ^a   Wang, Jing ^a   Li, Ying ^a   Li, Yongwen ^a   Wang, Min ^a   Chen, Jun ^a   Zhou, Qinghua ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; Animal model; Luciferase

Indexed keywords

GENOMIC DNA; LUCIFERASE; MESSENGER RNA; PROTEIN VEGFR 2 LUC; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; FEMALE; IMAGING; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROGENY; PROTEIN EXPRESSION; SEX DIFFERENCE; TESTIS; TRANSGENIC MOUSE; WOUND HEALING;

ANIMALS; FEMALE; GENES, REPORTER; LUCIFERASES; MALE; MICE; MICE, NUDE; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; WOUND HEALING;

EID: 79957672007     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: 10.3779/j.issn.1009-3419.2011.05.02     Document Type: Article

References (11)

1. Holmes K, Roberts OL, Thomas AM, et al. Vascular endothelial growth factor receptor-2: structure, function, intracellular signaling and therapeutic inhibition. Cell Signal, 2007, 19(10): 2003-2012.
2. Waldner MJ, Wirtz S, Jefremow A, et al. VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer. J Exp Med, 2010, 207(13): 2855-2868.
3. Sullivan LA, Carbon JG, Roland CL, et al. r84, a novel therapeutic antibody against mouse and human VEGF with potent anti-tumor activity and limited toxicity induction. PLoS One, 2010, 5(8): 12031.
4. Folkman J. Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov, 2007, 6(4): 273-286.
5. Zhang N, Fang Z, Contag PR, et al. Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse. Blood, 2004, 103(2): 617-626.
6. Ryan PL, Youngblood RC, Harvill J, et al. Photonic monitoring in real time of vascular endothelial growth factor receptor 2 gene expression under relaxin-induced conditions in a novel murine wound model. Ann N Y Acad Sci, 2005, 10(41): 398-414.
7. Ehrbar M, Zeisberger SM, Raeber GP, et al. The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis. Biomaterials, 2008, 29(ll): 1720-1729.
8. Angst E, Chen M, Mojadidi M, et al. Bioluminescence imaging of angiogenesis in a murine orthotopic pancreaticcancer model. Mol Imaging Biol, 2010, 12(6): 570-575.
9. Shih SC, Robinson GS, Perruzzi CA, et al. Molecular profiling of angiogenesis markers. Am J Pathol, 2002, I6l(l): 35-41.
10. Wong VW, Sorkin M, Glotzbach JP, et al. Surgical approaches to create murine models of human wound healing. J Biomed Biotechnol, 2011, 2011:969618.
11. Roy S, Khanna S, Sen CK. Redox regulation of the VEGF signaling path and tissue vascularization: Hydrogen peroxide, the common link between physical exercise and cutaneous wound healing. Free Radic Biol Med, 2008, 44(2): 180-192.