The role of hepatoprotective effect of a flavonoid-rich extract of Salvia plebeia R.Br. on carbon tetrachlorideinduced acute hepatic injury in mice

Journal of Medicinal Plants Research

Volumn 5, Issue 9, 2011, Pages 1558-1563

  Jin, Xiao feng ^a   Qian, Jie ^b   Lu, Yan hua ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b TONGJI UNIVERSITY   (China)

Author keywords

Flavonoids; Hepatoprotective activity; Histopathological; Salvia plebeia R. Brown (Lamiaceae)

Indexed keywords

BIFENDATE; CARBON TETRACHLORIDE; FLAVONOID; HISPIDULIN; HOMOPLANTAGININ; LIVER PROTECTIVE AGENT; LUTEOLIN; LUTEOLIN 7 GLUCOSIDE; NEPETIN; NEPITRIN; PLANT EXTRACT; SALVIA PLEBEIA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DOSE INCREASE; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; SALVIA; SALVIA PLEBEIA;

LAMIACEAE; MUS; SALVIA PLEBEIA;

EID: 79957647896     PISSN: 19960875     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Berry MN, Halls HJ, Grivell MB (1992). Techniques for the pharmacological and toxicological studies with isolated hepatocyte suspension. Life Sci., 51: 213.
2. Ferrandiz ML, Bustos G, Paya M, Gunasegaran R, Alcaraz MJ (1994). Hispidulin protection against hepatotoxicity induced by bromobenzene in mice. Life Sci., 55: 145-150.
3. Gu LW, Weng XC (2001). Antioxidant activity and components of Salvia plebeia R. Br.-a Chinese herb. Food Chem., 73: 299-305.
4. 4-induced liver damage. Biochem. Bioph. Res. Co., 329: 991-995.
5. Jin XF, Lu YH, Wei DZ, Wang ZT (2008). Chemical fingerprint and quantitative analysis of Salvia plebeia R. Br. by high-performance liquid chromatography. J. Pharmaceut. Biomed., 48: 100-104.
6. Jia ZS, Tang MC, Wu JM (1999). The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem., 64: 555-559.
7. Lin CC, Lin JK, Chang CH (1995). Evaluation of hepatoprotective effects of "Chhit-Chan-Than" from Taiwan. Int. J. Pharmacog., 33: 139-143.
8. Qu XJ, Xia X, Wang YX (2009). Protective effects of Salvia plebeia compound homoplantaginin on hepatocyte injury. Food Chem. Toxicol., 47: 1710-1715.
9. Ravikumar V, Shivashangari KS, Devaki T (2005). Hepatoprotective activity of Tridax procumbens against dgalactosamine/ lipopolysaccharide-induced hepatitis in rats. J. Ethnopharmacol., 101: 55-60.
10. Venkateswaran S, Pari L, Viswanathan P (1998). Anti peroxidation effect of Livex, a herbal formulation against erythromycin estolate induced lipid peroxidation in rats. Phytother. Res., 12: 465-471.
11. Weng XC, Wang W (2000). Antioxidant activity of compounds isolated from Salvia plebeia. Food Chem., 71: 489-493.
12. Wang N, Li PB, Wang YG, Peng W (2008). Hepatoprotective effect of Hypericum japonicum extract and its fractions. J. Ethnopharmacol., 116: 1-6.
13. Yuan LP, Chen FH, Ling L, Dou PF, Bo H, Zhong MM, Xia LJ (2008). Protective effects of total flavonoids of Bidens pilosa L. (TFB) on animal liver injury and liver fibrosis. J. Ethnopharmacol., 116: 539-546.
14. Zhang ZF, Liu Y, Luo P, Zhang HJ (2009). Separation and Purification of Two Flavone Glucuronides from Erigeron multiradiatus (Lindl.) Benth with Macroporous Resins. J. Biomed. Biotechnol., doi:10.1155/2009/875629.
15. Zou YP, Lu YH, Wei DZ (2004). Antioxidant Activity of a Flavonoid-Rich Extract of Hypericum perforatum L. in vitro. J. Agric. Food Chem., 52: 5032-5039.