Child abuse as a risk factor for suicide in life: A selective overview

Minerva Psichiatrica

Volumn 52, Issue 1, 2011, Pages 61-69

  Pompili, M ^a,b   Innamorati, M ^a   Venturini, P ^a   Serafini, G ^a   Lester, D ^c   Girardi, P ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b MCLEAN HOSPITAL   (United States)

^c RICHARD STOCKTON COLLEGE OF NEW JERSEY   (United States)

Author keywords

Child abuse; Epigenomics; Suicide

Indexed keywords

GLUCOCORTICOID RECEPTOR; MESSENGER RNA; RIBOSOME RNA; UNTRANSLATED RNA;

AGGRESSIVENESS; ALCOHOLISM; ANXIETY DISORDER; BIPOLAR DISORDER; CHILD ABUSE; CHILD PARENT RELATION; CHILD SEXUAL ABUSE; CHROMATIN; CYCLOTHYMIA; DNA METHYLATION; DYSTHYMIA; EPIGENETICS; GENE EXPRESSION; HIPPOCAMPUS; HISTONE MODIFICATION; HOPELESSNESS; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMPULSIVENESS; INTRACELLULAR SIGNALING; LIFE EVENT; MAJOR DEPRESSION; MALADJUSTMENT; NEGLECT; NONHUMAN; PROMOTER REGION; PROTEIN SYNTHESIS; REVIEW; RISK FACTOR; SELF REPORT; SEX DIFFERENCE; STRESS; SUBSTANCE ABUSE; SUICIDAL IDEATION; SUICIDE;

EID: 79957647870     PISSN: 03911772     EISSN: 18271731     Source Type: Journal    
DOI: None     Document Type: Review

References (51)

1. Pompili M, Tatarelli R, Lester D. The prevention of suicide is everybody's business: Willing is not enough, we must do. Minerva Psichiatr 2005;46:145-6.
2. Pompili M, Tatarelli R. Suicidio e suicidologia: uno sguardo al futuro. Minerva Psichiatr 2007;48:99-118.
3. De Bellis MD, Chrousos GP, Dorn LD, Burke L, Helmers K, Kling MA et al. Hypothalamic-pituitary-adrenal axis dysregulation in sexually abused girls. J Clin Endocrinol Metab 1994;78:249-55.
4. van Egmond M, Garnefski N, Jonker D, Kerkhof A. The relationship between sexual abuse and female suicidal behavior. Crisis 1993;14:129-39.
5. Beautrais AL. Suicide and serious suicide attempts in youth: a multiple-group comparison study. Am J Psychiatry 2003;160:1093-9.
6. Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF. Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 2004;82:217-25.
7. Joiner TE Jr, Sachs-Ericsson NJ, Wingate LR, Brown JS, Anestis MD, Selby EA. Childhood physical and sexual abuse and lifetime number of suicide attempts: a persistent and theoretically important relationship. Behav Res Ther 2007;45:539-47.
8. World Health Organization. Report of the Consultation on Child Abuse Prevention. WHO, Geneva, 29-31 March 1999. Geneva: World Health Organization; 1999.
9. Mann JJ, Bortinger J, Oquendo MA, Currier D, Li S, Brent DA. Family history of suicidal behavior and mood disorders in probands with mood disorders. Am J Psychiatry 2005;162:1672-9.
10. Zouk H, Tousignant M, Seguin M, Lesage A, Turecki G. Characterization of impulsivity in suicide completers: clinical, behavioral and psychosocial dimensions. J Affect Disord 2006;92:195-204.
11. Rogers JR. Sexual abuse and suicide: Why we may not know what we think we know. Arch Suicide Res 2003;7:83-91.
12. Widom CS, DuMont K, Czaja SJ. A prospective investigation of major depressive disorder and comorbidity in abused and neglected children grown up. Arch Gen Psychiatry 2007;64:49-56.
13. Fergusson DM, Horwood LJ, Lynskey MT. Childhood sexual abuse and psychiatric disorder in young adulthood: II. Psychiatric outcomes of childhood sexual abuse. J Am Acad Child Adolesc Psychiatry 1996;35:1365-74.
14. Afifi TO, Enns MW, Cox BJ, Asmundson GJ, Stein MB, Sareen J. Population attributable fractions of psychiatric disorders and suicide ideation and attempts associated with adverse childhood experiences, Am J Public Health 2008;98:946-52.
15. Wunderlich U, Bronisch T, Wittchen HU, Carter R. Gender differences in adolescents and young adults with suicidal behaviour. Acta Psychiatr Scand 2001;104:332-9.
16. Briere J, Zaidi LY. Sexual abuse histories and sequelae in female psychiatric emergency room patients. Am J Psychiatry 1989;146:1602-67
17. Bacskai E, Czobor P, Gerevich J. Suicidality and trait aggression related to childhood victimization in patients with alcoholism. Psychiatry Res 2009;165:103-10.
18. Hyun M, Friedman SD, Dunner DL. Relationship of childhood physical and sexual abuse to adult bipolar disorder. Bipolar Disord 2000;2:131-5.
19. Leverich GS, Altshuler LL, Frye MA, Suppes T, Keck PE Jr, McElroy SL, Denicoff KD et al. Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network. J Clin Psychiatry 2003;64:506-15.
20. Brown GR, McBride L, Bauer MS, Williford WO. Impact of childhood abuse on the course of bipolar disorder: a replication study in U.S. veterans. J Affect Disord 2005;89:57-67.
21. Pompili M, Iliceto P, Innamorati M, Rihmer Z, Lester D, Akiskal HS et al. Suicide risk and personality traits in physically and/or sexually abused acute psychiatric inpatients: a preliminary study. Psychol Rep 2009;105:554-68.
22. Pompili M, Rihmer Z, Akiskal HS, Innamorati M, Iliceto P, Akiskal KK et al. Temperament and personality dimensions in suicidal and nonsuicidal psychiatric inpatients. Psychopathology 2008;41:313-21.
23. Akiskal HS, Hantouche EG, Allilaire JF. Bipolar II with and without cyclothymic temperament: "dark" and "sunny" expressions of soft bipolarity. J Affect Disord 2003;73:49-57.
24. Kochman FJ, Hantouche EG, Ferrari P, Lancrenon S, Bayart D, Akiskal HS. Cyclothymic temperament as a prospective predictor of bipolarity and suicidality in children and adolescents with major depressive dis- order. J Affect Disord 2005;85:181-9.
25. Rihmer A, Rózsa S, Rihmer Z, Gonda X, Akiskal KK, Akiskal HS. Affective temperament-types and suicidal behaviour. Eur Psychiatry 2007;22(Suppl. 1):s244.
26. Pompili M, Innamorati M, Szanto K, Di Vittorio C, Conwell Y, Lester D et al. Life events as precipitants of suicide attempts among first-time suicide attempters, repeaters, and non-attempters. Psychiatry Res 2010 [Epub ahead of print].
27. Pompili M. Exploring the phenomenology of suicide. Suicide Life Threat Behav 2010;40:234-44.
28. Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am
29. Hardt J, Sidor A, Nickel R, Kappis B, Petrak P, Egle UT. Childhood adversities and suicide attempts: a retrospective study. J Fam Viol 2008;23:713-8.
30. Esposito CL, Clum GA. Social support and problem-solving as moderators of the relationship between childhood abuse and suicidality: applications to a delinquent population. J Trauma Stress 2002;15:137-46.
31. Meadows LA, Kaslow NJ. Hopelessness as mediator of the link between reports of a history of child maltreatment and suicidality in African American women. Cognitive Therapy and Research 2002;26:657-74.
32. Bebbington PE, Cooper C, Minot S, Brugha TS, Jenkins R, Meltzer H et al. Suicide attempts, gender, and sexual abuse: data from the 2000 British Psychiatric Morbidity Survey. Am J Psychiatry 2009;166:1135-40.
33. Tiet QQ, Finney JW, Moos RH. Recent sexual abuse, physical abuse, and suicide attempts among male veterans seeking psychiatric treatment. Psychiatr Serv 2006;57:107-13.
34. Seguin M, Lesage A, Turecki G, Bouchard M, Chawky N, Tremblay N et al. Life trajectories and burden of adversity: mapping the developmental profiles of suicide mortality, Psychol Med 2007;37:1575-83.
35. Bifulco A, Moran PM, Baines R, Bunn A, Stanford K. Exploring psychological abuse in childhood: II. Association with other abuse and adult clinical depression. Bull Menninger Clin 2002;66:241-58.
36. Rutter M. Nature, nurture, and development: from evangelism through science toward policy and practice. Child Dev 2002;73:1-21.
37. Briere J, Runtz M. Differential adult symptomatology associated with three types of child abuse histories. Child Abuse Negl 1990;14:357-64.
38. Bryant SL, Range LM. Suicidality in college women who report multiple versus single types of maltreatment by parents: A brief report. J Child Sex Abus 1995;4:87-94.
39. Rutter M. The interplay of nature, nurture, and developmental influences: the challenge ahead for mental health. Arch Gen Psychiatry 2002;59:996-1000.
40. Kendler KS, Gardner CO, Prescott CA. Toward a comprehensive developmental model for major depression in women. Am J Psychiatry 2002;159:1133-45.
41. Garno JL, Goldberg JF, Ramirez PM, Ritzler BA. Impact of childhood abuse on the clinical course of bipolar disorder. Br J Psychiatry 2005;186:121-5.
42. Cicchetti D, Rizley R. Developmental perspectives on the etiology, intergenerational transmission and sequelae of child maltreatment. New Directions in Child Development 1981;11:31-55.
43. Dube SR, Anda RF, Felitti VJ, Chapman DP, Williamson DF, Giles WH. Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: findings from the Adverse Childhood Experiences Study. JAMA 2001;286:3089-96.
44. Edwards VJ, Holden GW, Felitti VJ, Anda RF. Relationship between multiple forms of childhood maltreatment and adult mental health in community respondents: results from the adverse childhood experiences study. Am J Psychiatry 2003;160:1453-60.
45. Boye B, Bentsen H, Ulstein I, Notland TH, Lersbryggen A, Lingjaerde O et al. Relatives' distress and patients' symptoms and behaviours: a prospective study of patients with schizophrenia and their relatives. Acta Psychiatr Scand 2001;104:42-50.
46. Meaney MJ, Szyf M. Maternal care as a model for experience-dependent chromatin plasticity? Trends Neurosci 2005;28:456-63.
47. McGowan PO, Sasaki A, Huang TC, Unterberger A, Suderman M, Ernst C et al. Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One 2008;3:e2085.
48. McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonte B, Szyf M et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 2009;12:342-8.
49. Meaney MJ, Szyf M. Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome. Dialogues Clin Neurosci 2005;7:103-23.
50. Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR et al. Epigenetic programming by maternal behavior. Nat Neurosci 2004;7:847-54.
51. McGowan PO, Szyf M. The epigenetics of social adversity in early life: implications for mental health outcomes. Neurobiol Dis 2010;39:66-72.