Gestational and lactational transfer of melamine following gavage administration of a single dose to rats

Food and Chemical Toxicology

Volumn 49, Issue 7, 2011, Pages 1544-1548

  Chan, Judy Yuet Wa ^a   Lau, Chau Ming ^b   Ting, Tai Lun ^b   Mak, Thomas Chung Wai ^c   Chan, Michael Ho Ming ^a   Lam, Christopher Wai Kei ^a   Ho, Chung Shun ^a   Wang, Chi Chiu ^a   Fok, Tai Fai ^a   Fung, Kwok Pui ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b Homantin Government Offices   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Lactational; Maternal; Melamine; Placental

Indexed keywords

MELAMINE;

AMNION FLUID LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BREAST FEEDING; BREAST MILK; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEEDING; FEMALE; FETUS; FETUS (ANATOMY); GESTATION PERIOD; LACTATION; NONHUMAN; PLACENTAL TRANSFER; QUANTITATIVE ANALYSIS; RAT; TISSUE LEVEL;

AMNIOTIC FLUID; ANIMALS; ANIMALS, NEWBORN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; LACTATION; MATERNAL EXPOSURE; MATERNAL-FETAL EXCHANGE; MILK; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; TRIAZINES;

RATTUS;

EID: 79957647451     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.03.046     Document Type: Article

References (19)

1. Centre for Food Safety, HKSAR. Unsatisfactory results of testing of Melamine. Read at <>, 29 Oct 2008. http://www.cfs.gov.hk/tc_chi/whatsnew/whatsnew_fstr/files/melamine_oct/List_of_unsatisfactory_food_samples.pdf.
2. Dobson R.L., Motlagh S., Quijano M., Cambron R.T., Baker T.R., Pullen A.M., Regg B.T., Bigalow-Kern A.S., Vennard T., Fix A., Reimschuessel R., Overmann G., Shan Y., Daston G.P. Identification and characterization of toxicity of contaminants in pet food leading to an outbreak of renal toxicity in cats and dogs. Toxicological Sciences 2008, 106:251-262.
3. Dose Calculator. Assess at <>, 25 Sept 2008. http://www.accessdata.fda.gov/scripts/cder/onctools/animalquery.htm.
4. Filigenzi M.S., Tor E.R., Poppenga R.H., Aston L.A., Puschner B. The determination of melamine in muscle tissue by liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry 2007, 21:4027-4032.
5. Filigenzi M.S., Puschner B., Aston L.S., Poppenga R.H. Diagnostic determination of melamine and related compounds in kidney tissue by liquid chromatography/tandem mass spectrometry. Journal of Agricultural and Food Chemistry 2008, 56:7593-7599.
6. Heck H.D., Tyl R.W. The induction of bladder stones by terephthalic acid, dimethyl terephthalate, and melamine (2, 4, 6-triamino-s-triazine) and its relevance to risk assessment. Regulatory Toxicology and Pharmacology 1985, 5:294-313.
7. Ingelfinger J.R. Melamine and the global implications of food contamination. The New England Journal of Medicine 2008, 359:2745-2748.
8. Koch M.A. Experimental modeling and research methodology. The Laboratory Rat 2006, 587-626. Elsevier Academic Press. M.A. Suckow, S.H. Weisbroth, C.L. Franklin (Eds.).
9. OECD, 1998. Screening Information Data Set for Melamine, CAS No. 108-78-1. Read at <>, 17 Sept 2008. http://www.chem.unep.ch/irptc/sids/OECDSIDS/108781.pdf.
10. OECD, 1999. Screening Information Data Set for Isocyanuric acid, CAS No. 108-80-5. Read at <>, 17 Sept 2008. http://www.chem.unep.ch/irptc/sids/OECDSIDS/108805.pdf.
11. Ogasawara H., Imaida K., Ishiwata H., Toyoda K., Kawanishi T., Uneyama C., Hayashi S., Takahashi M., Hayashi Y. Urinary bladder carcinogenesis induced by melamine in F344 male rats: correlation between carcinogenicity and urolith formation. Carcinogenesis 1995, 16:2773-2777.
12. Parry J. China's tainted infant formula sickens nearly 13,000 babies. BMJ 2008, 337:a1802.
13. Reimschuessel R., Gieseker C.M., Miller R.A., Ward J., Boehmer J., Rummel N., Heller D.N., Nochetto C., de Alwis G.K., Bataller N., Andersen W.C., Turnipseed S.B., Karbiwnyk C.M., Satzger R.D., Crowe J.B., Wilber N.R., Reinhard M.K., Roberts J.F., Witkowski M.R. Evaluation of the renal effects of experimental feeding of melamine and cyanuric acid to fish and pigs. American Journal of Veterinary Research 2008, 69:1217-1228.
14. Smoker, M., Krynitsky, A.J., 2008. Interim method for determination of melamine and cyanuric acid residues in food using LC-MS/MS: Version 1.0. Laboratory Information Bulletin No. 4422. Read at <>, 25 Oct 2008. http://www.cfsan.fda.gov/~frf/lib4422.html.
15. Snyder, A., 2007. Protein Pretense. Scientific American Magazine, August.
16. Turnipseed, S., Casey, C., Nochetto, C., Heller, D.N., 2008. Determination of mlemaine and cyanuric acid residues in infant formula using LC-MS/MS. Laboratory Information Bulletin No. 4421, vol. 24. Read at <>, 25 Oct 2008. http://www.cfsan.fda.gov/~frf/lib4421.html.
17. US Food and Drug Administration. Interim Melamine and Analogues Safety/Risk Assessment. Read at <>, May 25, 2007. http://www.cfsan.fda.gov/~dms/melamra.html.
18. US Food and Drug Administration. FDA's Warnings/Advisories. Melamine Contamination in China. Updated 5 January 2009. Read at <>, 06 April 2009. http://www.fda.gov/oc/opacom/hottopics/melamine.html.
19. World Health Organization. Melamine and cyanuric acid: toxicity, preliminary risk assessment and guidance on levels in food. Read at <>, 25 Sept 2008. http://www.who.int/foodsafety/fs_management/Melamine.pdf.