Cytotoxicity and inhibition of platelet aggregation caused by an l-amino acid oxidase from Bothrops leucurus venom

Biochimica et Biophysica Acta - General Subjects

Volumn 1810, Issue 7, 2011, Pages 683-694

  Naumann, Gustavo B ^a   Silva, Liliana F ^a   Silva, Luciana ^a   Faria, Gilson ^a   Richardson, Michael ^a   Evangelista, Karla ^a   Kohlhoff, Markus ^a   Gontijo, Celia M F ^b,c   Navdaev, Alexei ^c   De Rezende, Flavia F ^c   Eble, Johannes A ^c   Sanchez, Eladio F ^a  

^a Ezequiel Dias Foundation   (Brazil)

^b Laboratory of Biomarkers and Monitoring   (Brazil)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Animal toxin; Apoptosis; Bl LAAO; L amino acid oxidase; Platelet function

Indexed keywords

AMINO ACID OXIDASE; CATALASE; HYDROGEN PEROXIDE; LEUCINE; METHIONINE; NORLEUCINE; PHENYLALANINE; SNAKE VENOM; TRYPTOPHAN;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BOTHROPS LEUCURUS; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEAMINATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; ENZYME PURIFICATION; HEMOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; ION EXCHANGE CHROMATOGRAPHY; ION EXCLUSION CHROMATOGRAPHY; LEISHMANIA; MOLECULAR SIZE; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE; SNAKE; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BOTHROPS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME STABILITY; HUMANS; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; L-AMINO ACID OXIDASE; LEISHMANIA BRAZILIENSIS; MOLECULAR SEQUENCE DATA; PLATELET AGGREGATION; SNAKE VENOMS; SUBSTRATE SPECIFICITY; TEMPERATURE;

ANIMALIA; BOTHROPS LEUCURUS; LEISHMANIA SP.;

EID: 79957628615     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2011.04.003     Document Type: Article

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