Intestinal hypoxia-inducible factor-2α (HIF-2α) is critical for efficient erythropoiesis

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19533-19540

  Anderson, Erik R ^a   Xue, Xiang ^a   Shah, Yatrik M ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLETE BLOOD COUNTS; GENETIC DISRUPTION; HIGH DEMAND; SMALL INTESTINE; WESTERN-BLOT ANALYSIS; WILD TYPES;

ABSORPTION; GENES; TRANSCRIPTION;

IRON;

HEMOGLOBIN; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IRON;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CELL COUNT; CONTROLLED STUDY; ENZYME ACTIVATION; ERYTHROCYTE COUNT; ERYTHROPOIESIS; GENE DISRUPTION; HEMATOCRIT; HUMAN; HUMAN CELL; IRON ABSORPTION; IRON BLOOD LEVEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SMALL INTESTINE; WESTERN BLOTTING; WILD TYPE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; ERYTHROCYTES; ERYTHROPOIESIS; HEMOGLOBINS; INTESTINAL ABSORPTION; INTESTINE, SMALL; IRON; KIDNEY; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION;

MUS;

EID: 79957616004     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.238667     Document Type: Article

References (46)

1. Jelkmann, W. E. (2011) J. Physiol. 589, 1251-1258
2. Dev, A., Fang, J., Sathyanarayana, P., Pradeep, A., Emerson, C., and Wojchowski, D. M. (2010) Blood 116, 5334-5346
3. Corwin, H. L. (2006) Transfus. Med. Rev. 20, 27-33
4. Tanno, T., and Miller, J. L. (2010) Adv. Hematol. 2010, 358283
5. Anderson, G. J., Powell, L. W., and Halliday, J. W. (1990) Gastroenterology 98, 576-585
6. Conrad, M. E., Weintraub, L. R., and Crosby, W. H. (1965) Blood 25, 990-998
7. Latunde-Dada, G. O., Vulpe, C. D., Anderson, G. J., Simpson, R. J., and McKie, A. T. (2004) Biochim. Biophys. Acta 1690, 169-176
8. Schmid, H., and Schiffl, H. (2010) Cardiovasc. Hematol. Agents Med. Chem. 8, 164-172
9. Weatherall, D. J. (1998) Baillieres Clin. Haematol. 11, 127-146
10. Gardenghi, S., Marongiu, M. F., Ramos, P., Guy, E., Breda, L., Chadburn, A., Liu, Y., Amariglio, N., Rechavi, G., Rachmilewitz, E. A., Breuer, W., Cabantchik, Z. I., Wrighting, D. M., Andrews, N. C., de Sousa, M., Giardina, P. J., Grady, R. W., and Rivella, S. (2007) Blood 109, 5027-5035
11. Latunde-Dada, G. O., Simpson, R. J., and McKie, A. T. (2008) J. Nutr. 138, 991-995
12. Mackenzie, B., and Garrick, M. D. (2005) Am. J. Physiol. Gastrointest. Liver Physiol. 289, G981-G986
13. McKie, A. T., Barrow, D., Latunde-Dada, G. O., Rolfs, A., Sager, G., Mudaly, E., Mudaly, M., Richardson, C., Barlow, D., Bomford, A., Peters, T. J., Raja, K. B., Shirali, S., Hediger, M. A., Farzaneh, F., and Simpson, R. J. (2001) Science 291, 1755-1759
14. Fleming, M. D., Trenor, C. C., 3rd, Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., and Andrews, N. C. (1997) Nat. Genet. 16, 383-386
15. Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., and Hediger, M. A. (1997) Nature 388, 482-488
16. Abboud, S., and Haile, D. J. (2000) J. Biol. Chem. 275, 19906-19912
17. Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., Law, T. C., Brugnara, C., Lux, S. E., Pinkus, G. S., Pinkus, J. L., Kingsley, P. D., Palis, J., Fleming, M. D., Andrews, N. C., and Zon, L. I. (2000) Nature 403, 776-781
18. Donovan, A., Lima, C. A., Pinkus, J. L., Pinkus, G. S., Zon, L. I., Robine, S., and Andrews, N. C. (2005) Cell Metab. 1, 191-200
19. McKie, A. T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., Miret, S., Bomford, A., Peters, T. J., Farzaneh, F., Hediger, M. A., Hentze, M. W., and Simpson, R. J. (2000) Mol. Cell 5, 299-309
20. Park, C. H., Valore, E. V., Waring, A. J., and Ganz, T. (2001) J. Biol. Chem. 276, 7806-7810
21. Krause, A., Neitz, S., Mägert, H. J., Schulz, A., Forssmann, W. G., Schulz-Knappe, P., and Adermann, K. (2000) FEBS Lett. 480, 147-150
22. Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., Ganz, T., and Kaplan, J. (2004) Science 306, 2090-2093
23. Gardenghi, S., Ramos, P., Marongiu, M. F., Melchiori, L., Breda, L., Guy, E., Muirhead, K., Rao, N., Roy, C. N., Andrews, N. C., Nemeth, E., Follenzi, A., An, X., Mohandas, N., Ginzburg, Y., Rachmilewitz, E. A., Giardina, P. J., Grady, R. W., and Rivella, S. (2010) J. Clin. Invest. 120, 4466-4477
24. Papanikolaou, G., Tzilianos, M., Christakis, J. I., Bogdanos, D., Tsimirika, K., MacFarlane, J., Goldberg, Y. P., Sakellaropoulos, N., Ganz, T., and Nemeth, E. (2005) Blood 105, 4103-4105
25. Kong, W. N., Chang, Y. Z., Wang, S. M., Zhai, X. L., Shang, J. X., Li, L. X., and Duan, X. L. (2008) J. Gastroenterol. 43, 136-143
26. Brasse-Lagnel, C., Karim, Z., Letteron, P., Bekri, S., Bado, A., and Beaumont, C. (2011) Gastroenterology 140, 1261-1271
27. Taylor, M., Qu, A., Anderson, E., Matsubara, T., Martin, A., Gonzalez, F. J., and Shah, Y. M. (March 18, 2011) Gastroenterology 10.1053/j.gastro.2011.03. 007
28. Chaston, T., Chung, B., Mascarenhas, M., Marks, J., Patel, B., Srai, S. K., and Sharp, P. (2008) Gut 57, 374-382
29. Mena, N. P., Esparza, A., Tapia, V., Valdés, P., and Núñez, M. T. (2008) Am. J. Physiol. Gastrointest. Liver Physiol. 294, G192-G198
30. Laftah, A. H., Ramesh, B., Simpson, R. J., Solanky, N., Bahram, S., Schümann, K., Debnam, E. S., and Srai, S. K. (2004) Blood 103, 3940-3944
31. Mastrogiannaki, M., Matak, P., Keith, B., Simon, M. C., Vaulont, S., and Peyssonnaux, C. (2009) J. Clin. Invest. 119, 1159-1166
32. Shah, Y. M., Matsubara, T., Ito, S., Yim, S. H., and Gonzalez, F. J. (2009) Cell Metab. 9, 152-164
33. Tian, H., McKnight, S. L., and Russell, D. W. (1997) Genes Dev. 11, 72-82
34. Ivan, M., Haberberger, T., Gervasi, D. C., Michelson, K. S., Günzler, V., Kondo, K., Yang, H., Sorokina, I., Conaway, R. C., Conaway, J. W., and Kaelin, W. G., Jr. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 13459-13464
35. Haase, V. H., Glickman, J. N., Socolovsky, M., and Jaenisch, R. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 1583-1588
36. Shah, Y. M., Ito, S., Morimura, K., Chen, C., Yim, S. H., Haase, V. H., and Gonzalez, F. J. (2008) Gastroenterology 134, 2036-2048
37. Torrance, J. D., and Bothwell, T. H. (1968) S. Afr. J. Med. Sci. 33, 9-11
38. Fatrai, S., Wierenga, A. T., Daenen, S. M., Vellenga, E., and Schuringa, J. J. (2011) Blood 117, 3320-3330
39. Bittorf, T., Jaster, R., Lüdtke, B., Kamper, B., and Brock, J. (1997) Cell. Signal. 9, 85-89
40. Kapitsinou, P. P., Liu, Q., Unger, T. L., Rha, J., Davidoff, O., Keith, B., Epstein, J. A., Moores, S. L., Erickson-Miller, C. L., and Haase, V. H. (2010) Blood 116, 3039-3048
41. Rankin, E. B., Biju, M. P., Liu, Q., Unger, T. L., Rha, J., Johnson, R. S., Simon, M. C., Keith, B., and Haase, V. H. (2007) J. Clin. Invest. 117, 1068-1077
42. Hodgkiss, R. J. (1998) Anticancer Drug Des. 13, 687-702
43. Koch, C. J. (2002) Methods Enzymol. 352, 3-31
44. Sato, Y., Endo, H., Okuyama, H., Takeda, T., Iwahashi, H., Imagawa, A., Yamagata, K., Shimomura, I., and Inoue, M. (2011) J. Biol. Chem. 286, 12524-12532
45. Pinto, J. P., Ribeiro, S., Pontes, H., Thowfeequ, S., Tosh, D., Carvalho, F., and Porto, G. (2008) Blood 111, 5727-5733
46. Peyssonnaux, C., Zinkernagel, A. S., Schuepbach, R. A., Rankin, E., Vaulont, S., Haase, V. H., Nizet, V., and Johnson, R. S. (2007) J. Clin. Invest. 117, 1926-1932