Vitiligo during treatment of Crohn's disease with adalimumab: Adverse effect or co-occurrence?

Case Reports in Dermatology

Volumn 3, Issue 1, 2011, Pages 28-31

  Posada, Celia ^a,d   Flórez, Ángeles ^a   Batalla, Ana ^a   Alcázar, Juan José ^b   Carpio, Daniel ^c  

^a Service of Dermatology   (Spain)

^b Service of Pathology   (Spain)

^c Services of Grastroenterology   (Spain)

^d HOSPITAL MONTECELO   (Spain)

Author keywords

Adalimumab; Anti tumor necrosis factor ; Cutaneous adverse effects; Vitiligo and Crohn's disease

Indexed keywords

ADALIMUMAB; ANTIBIOTIC AGENT; AZATHIOPRINE; MERCAPTOPURINE; METHOTREXATE;

ADULT; ARM; ARTICLE; CASE REPORT; CROHN DISEASE; DRUG WITHDRAWAL; FEMALE; HUMAN; PRIORITY JOURNAL; SKIN BIOPSY; THYROID DISEASE; TREATMENT OUTCOME; TREATMENT RESPONSE; TRUNK; UNSPECIFIED SIDE EFFECT; VITILIGO;

EID: 79957612201     PISSN: None     EISSN: 16626567     Source Type: Journal    
DOI: 10.1159/000324619     Document Type: Article

References (8)

1. Flendrie M, Vissers WH, Creemers MC, de Jong EM, van de Kerkhof PC, van Riel PL: Dermatological conditions during TNF-alpha-blocking therapy in patients with rheumatoid arthritis: a prospective study. Arthritis Res Ther 2005;7:R666-R676.
2. Exarchou SA, Voulgari PV, Markatseli TE, Zioga A, Drosos AA: Immune-mediated skin lesions in patients treated with anti-tumour necrosis factor alpha inhibitors. Scand J Rheumatol 2009;38:328-331.
3. Smith DI, Heffernan MP: Vitiligo after the resolution of psoriatic plaques during treatment with adalimumab. J Am Acad Dermatol 2008;58(2 suppl):S50-S52.
4. Raḿrez-Herńrdez M, Marras C, Mart́rez-Escribano JA: Infliximab-induced vitiligo. Dermatology 2005;210:79-80.
5. Lv Y, Li Q, Wang L, Gao T: Use of anti-tumor necrosis factor agents: a possible therapy for vitiligo. Med Hypotheses 2009;72:546-547.
6. Simón JA, Burgos-Vargas R: Vitiligo improvement in a patient with ankylosing spondylitis treated with infliximab. Dermatology 2008;216:234-235. (Pubitemid 351416724)
7. Alkhateeb A, Fain PR, Thody A, Bennett DC, Spritz RA: Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res 2003;16:208-214. (Pubitemid 36597056)
8. Pashankar D, Prendiville J, Israel DM: Vitiligo and Crohn's disease in children. J Pediatr Gastroenterol Nutr 1999;28:227-229. (Pubitemid 29293696)