Expression and localization of insulin receptors in dissociated primary cultures of rat Schwann cells

Cell Biology International

Volumn 35, Issue 3, 2011, Pages 299-304

  Shetter, Abhijth Ravindranath ^a   Muttagi, Gopal ^a   Sagar, Chandrasekhar Bhadravathi Kenchappa ^b  

^a DAVANGERE UNIVERSITY   (India)

^b NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Insulin receptor; Localization; Myelination; Plasma membrane; Schwann cell

Indexed keywords

INSULIN RECEPTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BASEMENT MEMBRANE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CYTOPLASM; EXON; IMMUNOREACTIVITY; MOLECULAR WEIGHT; NEURITIS; NEWBORN; NONHUMAN; PERIPHERAL NERVE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN RNA BINDING; RAT; RECEPTOR BINDING; SCHWANN CELL;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; CELLS, CULTURED; EXONS; IMMUNOHISTOCHEMISTRY; PROTEIN ISOFORMS; RATS; RECEPTOR, INSULIN; SCHWANN CELLS;

ORYCTOLAGUS CUNICULUS; RATTUS;

EID: 79957593742     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20100523     Document Type: Article

References (34)

1. Brockes JP, Fields K, Raff MC. Studies on cultured rat Schwann cells. I. Establishment of purified population from cultures of peripheral nerves. Brain Res 1979;165:105-18.
2. Coopersmith R, Leon M. Glycogen phosphorylase activity in the olfactory bulb of the young rat. J Comp Neurol 1987;261:148-54.
3. Czech MP. The nature and regulation of the insulin receptor: Structure and function. Ann Rev Physiol 1985;47:357-81.
4. Devaskar SU, Giddings SJ, Rajakumar PA, Carnaghi LR, Menon RK, Zahm DS. Insulin gene expression and insulin synthesis in mammalian neuronal cells. J Biol Chem 1994;269:8445-54.
5. Einheber S, Milner TA, Giancotti F, Salzer JL. Axonal regulation of Schwann cell integrin expression suggests a role for alpha 6 beta 4 in myelination. J Cell Biol 1993;123:1223-36.
6. Feltri ML, Scherer SS, Nemni R, Kamholz J, Vogelbacker H, Scott MO et al. Beta 4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent. Development 1994;120:1287-301.
7. Fernyhough P, Willars GB, Lindsay RM, Tomlinson DR. Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurons. Brain Res 1993;607:117-24.
8. Heidenreich KA, Zahniser N, Behrann P, Brandenburg D, Olefsky JM. Structural differences between insulin receptors in the brain and peripheral target tissues. J Biol Chem 1983;258:8527-30.
9. Hendricks SA, Agardh CD, Taylor SI, Roth J. Unique features of the insulin receptor in rat brain. J Neurochem 1984;43:1302-9.
10. Hwang JB, Frost SC. Effect of alternative glycosylation on insulin receptor processing. J Biol Chem 1999;274:22813-20.
11. Ishii DN. Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy. Brain Res Brain Res Rev 1995;20:47-67.
12. Jonas EA, Knox RJ, Kaczmarek LK, Schwartz JH. Insulin Receptor in Aplysia neurons: characterization, molecular cloning, and modulation of ion currents. J Neurosci 1996;16:1645-58.
13. Joose M, Biosca JA, Trujillo R, Itartee E. Characterization of the hepatic insulin receptor undergoing internalization through clathrin-coated vesicles and endosomes. FEBS Lett 1993;334:286-8.
14. 125I- Insulin to rat Schwann cells in vitro. Fed Am Soc Exp Biol 1982;4771.
15. Koch L, Wunderlich FT, Seibler J, Konner AC, Hampel B, Irlenbusch S et al. Central insulin action regulates peripheral glucose and fat metabolism in mice. J Clin Invest 2008;118:2132-47.
16. Lai C, Lemke G. An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron 1991;6:691-704.
17. Lowe W Jr, LeRoith D. Insulin receptors from guinea pig liver and brain: structural and functional studies. Endocrinology 1986;118:1669-77.
18. McClain DA, Olefsky JM. Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells. Diabetes 1988;37:806-15.
19. Mielke JG, Wang YT. Insulin exerts neuroprotection by counteracting the decrease in cell-surface GABA receptors following oxygen-glucose deprivation in cultured cortical neurons. J Neurochem 2005;92:103-13.
20. Obici S, Zhang BB, Karkanias G, Rossetti L. Hypothalamic insulin signalling is required for inhibition of glucose production. Nat Med 2002;8:1376-82.
21. Perrin C, Knauf C, Burcelin R. Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-Dribofuranoside, controls muscle glycogen synthesis. Endocrinology 2004;145:4025-33.
22. Plum L, Schubert M, Bruning JC. The role of insulin receptor signalling in the brain. Trends Endocrin Met 2005;16:59-65.
23. Recio-Pinto E, Rechler MM, Ishii DN. Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. J Neurosci 1986;6:1211-9.
24. Rulifson EJ, Kim SK, Nusse R. Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science 2002;296:1118-20.
25. Schlessinger J, Ullrich A. Growth factor signaling by receptor tyrosine kinases. Neuron 1992;9:383-91.
26. Singhal A, Cheng C, Sun H, Zochodne DW. Near nerve local insulin prevents conduction slowing in experimental diabetes. Brain Res 1997;763:209-14.
27. Sugimoto K, Murakawa Y, Zhang W, Xu G, Sima AAF. Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms. Diabetes Metab Res Rev 2000;16:354-63.
28. Sugimoto K, Murakawa Y, Sima AAF. Expression and localization of insulin receptor in rat dorsal root ganglion and spinal cord. J Peripher Nerv Sys 2002;7:44-53.
29. Ullrich A, Bell JR, Chen EY, Herrera R, Petruzelli LM, Dull TJ et al. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature 1985;313:756-61.
30. Unger JW, Livingston JN, Moss AM. Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects. Prog Neurobiol 1991;36:343-62.
31. Waldbillig RJ, LeRoith D. Insulin receptors in the peripheral nervous system: a structural and functional analysis. Brain Res 1987;409:215-20.
32. White MF. Insulin signaling in health and disease. Science 2003;302:1710-11.
33. Zackenfels K, Oppenheim RW, Rohrer H. Evidence for an important role of IGF-I and IGF-II for the early development of chick sympathetic neurons. Neuron 1995;14:731-41.
34. Zhao WQ, Alkon DL. Role of insulin and insulin receptor in learning and memory. Mol Cell Endocrinol 2001;177:125-34.