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Volumn 52, Issue 26, 2011, Pages 3266-3270

An improved synthesis of 2-oxa-7-azaspiro[3,5]nonane and analogs as novel reagents in medicinal chemistry

Author keywords

2 Oxa 6 azaspiro 3,4 octane; 2 Oxa 6 azaspiro 3,5 nonane; 2 Oxa 7 azaspiro 3,5 nonane; Spirocyclic oxetane

Indexed keywords

2 OXA 6 AZASPIRO[3,4]OCTANE; 2 OXA 6 AZASPIRO[3,5]NONANE; 2 OXA 7 AZASPIRO[3,5]NONANE; OXETANE DERIVATIVE; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CHROMATOGRAPHY; DRUG PURIFICATION; DRUG SYNTHESIS;

EID: 79957582977 PISSN: 00404039 EISSN: 18733581 Source Type: Journal
DOI: 10.1016/j.tetlet.2011.04.054 Document Type: Article

Times cited : (12)

References (11)

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- The mother liquor still contained the desired product but was not further purified
- The mother liquor still contained the desired product but was not further purified.

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- 3N followed by the treatment with NaH led to the desired product 14 in 38% yield according to Ref. [8]
- 3N followed by the treatment with NaH led to the desired product 14 in 38% yield according to Ref. [8].

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