Improvement of platelet dysfunction in chronic myelogenous leukemia following treatment with imatinib: A case report

Journal of Medical Case Reports

Volumn 5, Issue , 2011, Pages

  Shimabukuro Vornhagen, Alexander ^a   Rothe, Achim ^a   Nogova, Lucia ^a   Kochanek, Matthias ^a   Scheid, Christoph ^a   Von Bergwelt Baildon, Michael ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYUREA; IMATINIB; LACTATE DEHYDROGENASE; MORPHINE;

ABDOMINAL PAIN; ADULT; ARTICLE; BONE MARROW BIOPSY; CANCER CHEMOTHERAPY; CANCER SURGERY; CASE REPORT; CELL STRUCTURE; CHROMOSOME ANALYSIS; CHRONIC MYELOID LEUKEMIA; DYSPNEA; GRANULOPOIESIS; HEMATOMA; HUMAN; INTERNATIONAL NORMALIZED RATIO; LEUKAPHERESIS; MALE; NIGHT SWEAT; PALLOR; PARTIAL THROMBOPLASTIN TIME; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; SPLENOMEGALY; TACHYCARDIA; THROMBOCYTE DYSFUNCTION; WEIGHT REDUCTION;

EID: 79957564235     PISSN: 17521947     EISSN: 17521947     Source Type: Journal    
DOI: 10.1186/1752-1947-5-215     Document Type: Article

References (12)

1. The relationship between the type of bcr-abl hybrid messenger RNA and thrombopoiesis in Philadelphia-positive chronic myelogenous leukemia. K Inokuchi T Nomura, Leuk Lymphoma 1993 10 9 15 8374529 (Pubitemid 23239853)
2. + cells from patients with chronic myeloid leukemia. V Maguer-Satta AL Petzer AC Eaves CJ Eaves, Blood 1996 88 1796 1804 8781437 (Pubitemid 26307077)
3. Detection of the bcr/abl gene in bone marrow macrophages in CML and alterations during interferon therapy: a fluorescence in situ hybridization study on trephine biopsies. J Thiele B Schmitz R Fuchs HM Kvasnicka J Lorenzen R Fischer, J Pathol 1998 186 331 335 10.1002/(SICI)1096-9896(199811)186:3<331: :AID-PATH178>3.0.CO;2-7 10211125 (Pubitemid 28494364)
4. The possible influences of B2A2 and B3A2 BCR/ABL protein structure on thrombopoiesis in chronic myeloid leukaemia. RA Perego M Costantini G Cornacchini L Gargantini C Bianchi E Pungolino E Rovida E Morra, Eur J Cancer 2000 36 1395 1401 10.1016/S0959-8049(00)00128-3 10899653 (Pubitemid 30421144)
5. Clinical features at diagnosis in 430 patients with chronic myeloid leukaemia seen at a referral centre over a 16-year period. DG Savage RM Szydlo JM Goldman, Br J Haematol 1997 96 111 116 10.1046/j.1365-2141.1997.d01-1982.x 9012696
6. Bleeding and thrombosis in the myeloproliferative disorders. AI Schafer, Blood 1984 64 1 12 6375757 (Pubitemid 14085720)
7. Fluorescence in-situ hybridization (FISH) reveals that in chronic myelogenous leukaemia (CML) following interferon- therapy, normalization of megakaryocyte size is associated with the loss of bcr/abl translocation. J Thiele B Schmitz H Gross HM Kvasnicka N Niederle LD Leder R Fischer, Histopathology 1997 31 215 221 10.1046/j.1365-2559.1997.2480853.x 9354890 (Pubitemid 27397913)
8. Treatment of chronic myelogenous leukemia with the tyrosine kinase inhibitor STI571 results in marked regression of bone marrow fibrosis. C Beham-Schmid U Apfelbeck H Sill O Tsybrovsky G Höfler OA Haas W Linkesch, Blood 2002 99 381 383 10.1182/blood.V99.1.381 11756197
9. Megakaryocyte features and bcr/abl translocation in chronic myeloid leukemia following imatinib mesylate (STI571) therapy: a fluorescence in-situ hybridization study. J Thiele HM Kvasnicka E Varus E Ollig A Schmitt-Graeff P Staib M Griesshammer, Leuk Lymphoma 2004 45 1627 1631 10.1080/ 10428190410001683732 15370216 (Pubitemid 38886007)
10. Megakaryocytes carry the fused bcr-abl gene in chronic myeloid leukaemia: a fluorescence in situ hybridization analysis from bone marrow biopsies. M Nolte M Werner M Ewig R von Wasielewski H Link H Diedrich A Georgii, Virchows Arch 1996 427 561 565 8605566 (Pubitemid 26109206)
11. Bcr-Abl is a "molecular switch" for the decision for growth and differentiation in hematopoietic stem cells. T Era, Int J Hematol 2002 76 35 43 10.1007/BF02982716 12138893 (Pubitemid 43020278)
12. BCR-ABL. D Buet H Raslova JF Geay P Jarrier V Lazar A Turhan F Morlé W Vainchenker F Louache, Leukemia 2007 21 917 925 17315025 (Pubitemid 46672067)