Immune surveillance of the normal human CNS takes place in dependence of the locoregional blood-brain barrier configuration and is mainly performed by CD3+/CD8+ lymphocytes

Neuropathology

Volumn 31, Issue 3, 2011, Pages 230-238

  Loeffler, Christian ^a   Dietz, Klaus ^b   Schleich, Ariane ^a   Schlaszus, Holger ^a   Stoll, Manuel ^a   Meyermann, Richard ^a   Mittelbronn, Michel ^c  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

Blood brain barrier; CD3; CD8; CNS; Immune surveillance

Indexed keywords

BIOLOGICAL MARKER; GRANZYME B; PERFORIN; TRANSCRIPTION FACTOR FOXP3;

ADULT; AGED; ARTICLE; BLOOD BRAIN BARRIER; BRAIN REGION; CAUSE OF DEATH; CD3+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOSURVEILLANCE; MALE; MICROSCOPY; PHENOTYPE; PRIORITY JOURNAL;

ADULT; AGE FACTORS; AGED; ANTIGENS, CD3; ANTIGENS, CD8; BLOOD-BRAIN BARRIER; CD8-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MALE; MIDDLE AGED; SEX FACTORS; YOUNG ADULT;

EID: 79957558474     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2010.01167.x     Document Type: Article

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