Clinical treatment of ocular Demodex folliculorum by systemic ivermectin

American Journal of Ophthalmology

Volumn 151, Issue 6, 2011, Pages

  Holzchuh, Flávio Gaieta ^a,b   Hida, Richard Yudi ^a,b   Moscovici, Bernardo Kaplan ^a,b   Villa Albers, Marcos Bottene ^a,b   Santo, Ruth Miyuki ^a   Kara José, Newton ^a   Holzchuh, Ricardo ^a,b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FACULDADE DE CIÊNCIAS MÉDICAS DA SANTA CASA DE SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN; IVERMECTIN; ROSE BENGAL;

ADULT; ARTICLE; BLEPHARITIS; CLINICAL ARTICLE; DEMODEX; DEMODEX FOLLICULORUM; DRUG EFFICACY; FEMALE; HUMAN; MALE; MITE INFESTATION; NONHUMAN; OUTCOME ASSESSMENT; PARASITE EXAMINATION; PARASITE LOAD; PRIORITY JOURNAL; REPEATED DRUG DOSE; SCHIRMER TEST; SINGLE DRUG DOSE; SYSTEMIC THERAPY; TEAR FILM; TEAR FILM BREAK UP TIME; TEAR MENISCUS HEIGHT; VISUAL SYSTEM EXAMINATION;

EID: 79957541183     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2010.11.024     Document Type: Article

References (37)

1. Boge-Rasmussen T, Christensen JD, Gluud B, Kristensen G, Norn MS. Demodex folliculorum hominis (Simon): incidence in a normomaterial and in patients under systemic treatment with erythromycin or glucocorticoid. Acta Derm Venereol 1982;62(5):454-456. (Pubitemid 12024343)
2. English FP, Nutting WB. Feeding characteristics in demodectic mites of the eyelid. Aust J Ophthalmol 1981;9(4):311-313. (Pubitemid 12135648)
3. English FP, Nutting WB. Demodicosis of ophthalmic concern. Am J Ophthalmol 1981;91(3):362-372. (Pubitemid 11147127)
4. English FP, Zhang GW, McManus DP, Campbell P. Electron microscopic evidence of acarine infestation of the eyelid margin. Am J Ophthalmol 1990;109(2):239-240. (Pubitemid 20048435)
5. Coston TO. Demodex folliculorum blepharitis. Trans Am Ophthalmol Soc 1967;65:361-392.
6. Forstinger C, Kittler H, Binder M. Treatment of rosacea-like demodicidosis with oral ivermectin and topical permethrin cream. J Am Acad Dermatol 1999;41(5 Pt 1):775-777. (Pubitemid 29514037)
7. Forton F, Seys B. Density of Demodex folliculorum in rosacea: a case-control study using standardized skin-surface biopsy. Br J Dermatol 1993;128(6):650-659. (Pubitemid 23172024)
8. Kamoun B, Fourati M, Feki J, et al. [Blepharitis due to Demodex: myth or reality?]. J Fr Ophtalmol 1999;22(5):525-527.
9. McCulley JP, Shine WE. Changing concepts in the diagnosis and management of blepharitis. Cornea 2000;19(5):650-658.
10. Rebora A. The management of rosacea. Am J Clin Dermatol 2002;3(7):489-496. (Pubitemid 35007066)
11. Norn MS. [Demodex folliculorum. Distribution of hair-follicle mites on the human body]. Ugeskr Laeger 1970;132(45):2123-2126.
12. Norn MS. Demodex folliculorum. Incidence and possible pathogenic role in the human eyelid. Acta Ophthalmol Suppl 1970;108:7-85.
13. Norn MS. Incidence of Demodex folliculorum on skin of lids and nose. Acta Ophthalmol (Copenh) 1982;60(4):575-583. (Pubitemid 12046953)
14. Czepita D, Kuzna-Grygiel W, Czepita M, Grobelny A. Demodex folliculorum and Demodex brevis as a cause of chronic marginal blepharitis. Ann Acad Med Stetin 2007; 53(1):63-67, discussion 67.
15. Dougherty JM, McCulley JP. Bacterial lipases and chronic blepharitis. Invest Ophthalmol Vis Sci 1986;27(4):486-491. (Pubitemid 16116292)
16. English FP. The role of the acarid Demodex folliculorum in ophthalmology. Trans Aust Coll Ophthalmol 1970;2:89-92.
17. Gao YY, Di Pascuale MA, Li W, et al. In vitro and in vivo killing of ocular Demodex by tea tree oil. Br J Ophthalmol 2005;89(11):1468-1473.
18. Gao YY, Di Pascuale MA, Li W, et al. High prevalence of Demodex in eyelashes with cylindrical dandruff. Invest Ophthalmol Vis Sci 2005;46(9):3089-3094. (Pubitemid 44264292)
19. Kheirkhah A, Casas V, Li W, Raju VK, Tseng SC. Corneal manifestations of ocular Demodex infestation. Am J Ophthalmol 2007;143(5):743-749.
20. Shimazaki J, Sakata M, Tsubota K. Ocular surface changes and discomfort in patients with meibomian gland dysfunction. Arch Ophthalmol 1995;113(10):1266-1270.
21. Ayres S Jr, Ayres S 3rd. Demodectic eruptions (demodicidosis) in the human. 30 years' experience with 2 commonly unrecognized entities: pityriasis folliculorum (Demodex) and acne rosacea (Demodex type). Arch Dermatol 1961;83:816-827.
22. Hasegawa T. A case report of the management of demodicosis in the golden hamster. J Vet Med Sci 1995;57(2):337-338.
23. Hoekzema R, Hulsebosch HJ, Bos JD. Demodicidosis or rosacea: what did we treat? Br J Dermatol 1995;133(2):294-299.
24. Persi A, Rebora A. Metronidazole and Demodex folliculorum. Acta Derm Venereol 1981;61(2):182-183. (Pubitemid 11147578)
25. Baima B, Sticherling M. Demodicidosis revisited. Acta Derm Venereol 2002;82(1):3-6. (Pubitemid 34450535)
26. Dominey A, Tschen J, Rosen T, Batres E, Stern JK. Pityriasis folliculorum revisited. J Am Acad Dermatol 1989;21(1):81-84. (Pubitemid 19171470)
27. Gao YY, Di Pascuale MA, Elizondo A, Tseng SC. Clinical treatment of ocular demodicosis by lid scrub with tea tree oil. Cornea 2007;26(2):136-143. (Pubitemid 46168279)
28. Pacque M, Munoz B, Greene BM, et al. Safety of and compliance with community-based ivermectin therapy. Lancet 1990;335(8702):1377-1380. (Pubitemid 20236986)
29. Toda I, Tsubota K. Practical double vital staining for ocular surface evaluation. Cornea 1993;12(4):366-367.
30. English FP, Iwamoto T, Darrell RW, DeVoe AG. The vector potential of Demodex folliculorum. Arch Ophthalmol 1970;84(1):83-85.
31. Fulk GW, Murphy B, Robins MD. Pilocarpine gel for the treatment of demodicosis - a case series. Optom Vis Sci 1996;73(12):742-745. (Pubitemid 27024192)
32. Pflugfelder SC, Tseng SC, Sanabria O, et al. Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation. Cornea 1998;17(1):38-56. (Pubitemid 28047008)
33. Nichols KK, Nichols JJ, Mitchell GL. The lack of association between signs and symptoms in patients with dry eye disease. Cornea 2004;23(8):762-770. (Pubitemid 39447304)
34. Bjerrum KB. Test and symptoms in keratoconjunctivitis sicca and their correlation. Acta Ophthalmol Scand 1996;74(5):436-441. (Pubitemid 26390485)
35. Adatia FA, Michaeli-Cohen A, Naor J, et al. Correlation between corneal sensitivity, subjective dry eye symptoms and corneal staining in Sjogren's syndrome. Can J Ophthalmol 2004;39(7):767-771. (Pubitemid 40115579)
36. Uyttebroeck W, Nijs I, Maudgal PC, Missotten L. Incidence of Demodex folliculorum on the eyelash follicle in normal people and in blepharitis patients. Bull Soc Belge Ophtalmol 1982;201:83-87.
37. Fernandes JBVD, Gorn PGV, Matayoshi S. Tratamento de fitiríase palpebral com ivermectina. Arq Bras Oftalmol 2001;64(2):157-158.