메뉴 건너뛰기




Volumn 53, Issue 6, 2011, Pages 1846-1853

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion

Author keywords

[No Author keywords available]

Indexed keywords

CD81 ANTIGEN; GLYCOPROTEIN E2; INTERLEUKIN 2; METHYL BETA CYCLODEXTRIN; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA INHIBITOR; TETRASPANIN;

EID: 79957504614     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24327     Document Type: Article
Times cited : (17)

References (41)
  • 1
    • 0027153210 scopus 로고
    • Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism
    • Wang C, Sarnow P, Siddiqui A. Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism. J Virol 1993; 67: 3338-3344.
    • (1993) J Virol , vol.67 , pp. 3338-3344
    • Wang, C.1    Sarnow, P.2    Siddiqui, A.3
  • 2
    • 37849185517 scopus 로고    scopus 로고
    • Intracellular accumulation of hepatitis C virus proteins in a human hepatoma cell line
    • Brazzoli M, Crotta S, Bianchi A, Bagnoli F, Monaghan P, Wileman T, et al. Intracellular accumulation of hepatitis C virus proteins in a human hepatoma cell line. J Hepatol 2007; 46: 53-59.
    • (2007) J Hepatol , vol.46 , pp. 53-59
    • Brazzoli, M.1    Crotta, S.2    Bianchi, A.3    Bagnoli, F.4    Monaghan, P.5    Wileman, T.6
  • 3
    • 25844523297 scopus 로고    scopus 로고
    • Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
    • Simmonds P, Bukh J, Combet C, Deleage G, Enomoto N, Feinstone S, et al. Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. HEPATOLOGY 2005; 42: 962-973.
    • (2005) HEPATOLOGY , vol.42 , pp. 962-973
    • Simmonds, P.1    Bukh, J.2    Combet, C.3    Deleage, G.4    Enomoto, N.5    Feinstone, S.6
  • 5
    • 17944385968 scopus 로고    scopus 로고
    • Structure-function analysis of hepatitis C virus envelope-CD81 binding
    • Petracca R, Falugi F, Galli G, Norais N, Rosa D, Campagnoli S, et al. Structure-function analysis of hepatitis C virus envelope-CD81 binding. J Virol 2000; 74: 4824-4830.
    • (2000) J Virol , vol.74 , pp. 4824-4830
    • Petracca, R.1    Falugi, F.2    Galli, G.3    Norais, N.4    Rosa, D.5    Campagnoli, S.6
  • 6
    • 0031895778 scopus 로고    scopus 로고
    • CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system
    • Levy S, Todd SC, Maecker HT. CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Annu Rev Immunol 1998; 16: 89-109.
    • (1998) Annu Rev Immunol , vol.16 , pp. 89-109
    • Levy, S.1    Todd, S.C.2    Maecker, H.T.3
  • 7
  • 8
    • 23044434951 scopus 로고    scopus 로고
    • Hepatitis C virus and non-Hodgkin's lymphoma 10 years later
    • Mazzaro C, Tirelli U, Pozzato G. Hepatitis C virus and non-Hodgkin's lymphoma 10 years later. Dig Liver Dis 2005; 37: 219-226.
    • (2005) Dig Liver Dis , vol.37 , pp. 219-226
    • Mazzaro, C.1    Tirelli, U.2    Pozzato, G.3
  • 9
    • 23944485662 scopus 로고    scopus 로고
    • Evasion of intracellular host defence by hepatitis C virus
    • Gale M Jr, Foy EM. Evasion of intracellular host defence by hepatitis C virus. Nature 2005; 436: 939-945.
    • (2005) Nature , vol.436 , pp. 939-945
    • Gale Jr, M.1    Foy, E.M.2
  • 10
    • 77953960796 scopus 로고    scopus 로고
    • Hepatitis C virus evasion of adaptive immune responses: a model for viral persistence
    • Burke KP, Cox AL. Hepatitis C virus evasion of adaptive immune responses: a model for viral persistence. Immunol Res 2010; 47: 216-227.
    • (2010) Immunol Res , vol.47 , pp. 216-227
    • Burke, K.P.1    Cox, A.L.2
  • 11
    • 70349245146 scopus 로고    scopus 로고
    • Intracellular innate immune cascades and interferon defenses that control hepatitis C virus
    • Horner SM, Gale M Jr. Intracellular innate immune cascades and interferon defenses that control hepatitis C virus. J Interferon Cytokine Res 2009; 29: 489-498.
    • (2009) J Interferon Cytokine Res , vol.29 , pp. 489-498
    • Horner, S.M.1    Gale Jr, M.2
  • 12
    • 0027971622 scopus 로고
    • CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection
    • Matloubian M, Concepcion RJ, Ahmed R. CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection. J Virol 1994; 68: 8056-8063.
    • (1994) J Virol , vol.68 , pp. 8056-8063
    • Matloubian, M.1    Concepcion, R.J.2    Ahmed, R.3
  • 14
    • 0035914925 scopus 로고    scopus 로고
    • Determinants of viral clearance and persistence during acute hepatitis C virus infection
    • Thimme R, Oldach D, Chang KM, Steiger C, Ray SC, Chisari FV. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med 2001; 194: 1395-1406.
    • (2001) J Exp Med , vol.194 , pp. 1395-1406
    • Thimme, R.1    Oldach, D.2    Chang, K.M.3    Steiger, C.4    Ray, S.C.5    Chisari, F.V.6
  • 15
    • 32044444819 scopus 로고    scopus 로고
    • The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration
    • Volkov Y, Long A, Freeley M, Golden-Mason L, O'Farrelly C, Murphy A, et al. The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration. Gastroenterology 2006; 130: 482-492.
    • (2006) Gastroenterology , vol.130 , pp. 482-492
    • Volkov, Y.1    Long, A.2    Freeley, M.3    Golden-Mason, L.4    O'Farrelly, C.5    Murphy, A.6
  • 16
    • 0035879345 scopus 로고    scopus 로고
    • Cutting edge: protein kinase C beta expression is critical for export of Il-2 from T cells
    • Long A, Kelleher D, Lynch S, Volkov Y. Cutting edge: protein kinase C beta expression is critical for export of Il-2 from T cells. J Immunol 2001; 167: 636-640.
    • (2001) J Immunol , vol.167 , pp. 636-640
    • Long, A.1    Kelleher, D.2    Lynch, S.3    Volkov, Y.4
  • 17
    • 0042854695 scopus 로고    scopus 로고
    • Protein kinase Cbeta1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion
    • Dreikhausen UE, Gorf K, Resch K, Szamel M. Protein kinase Cbeta1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion. Int Immunol 2003; 15: 1089-1098.
    • (2003) Int Immunol , vol.15 , pp. 1089-1098
    • Dreikhausen, U.E.1    Gorf, K.2    Resch, K.3    Szamel, M.4
  • 18
    • 17844371667 scopus 로고    scopus 로고
    • Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection
    • Semmo N, Day CL, Ward SM, Lucas M, Harcourt G, Loughry A, et al. Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection. HEPATOLOGY 2005; 41: 1019-1028.
    • (2005) HEPATOLOGY , vol.41 , pp. 1019-1028
    • Semmo, N.1    Day, C.L.2    Ward, S.M.3    Lucas, M.4    Harcourt, G.5    Loughry, A.6
  • 19
    • 0032832514 scopus 로고    scopus 로고
    • Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C
    • Gerlach JT, Diepolder HM, Jung MC, Gruener NH, Schraut WW, Zachoval R, et al. Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C. Gastroenterology 1999; 117: 933-941.
    • (1999) Gastroenterology , vol.117 , pp. 933-941
    • Gerlach, J.T.1    Diepolder, H.M.2    Jung, M.C.3    Gruener, N.H.4    Schraut, W.W.5    Zachoval, R.6
  • 20
    • 22544470874 scopus 로고    scopus 로고
    • Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
    • Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, Zhao Z, et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 2005; 11: 791-796.
    • (2005) Nat Med , vol.11 , pp. 791-796
    • Wakita, T.1    Pietschmann, T.2    Kato, T.3    Date, T.4    Miyamoto, M.5    Zhao, Z.6
  • 21
    • 1842864089 scopus 로고    scopus 로고
    • Phage display selection on whole cells yields a small peptide specific for HCV receptor human CD81
    • Cao J, Zhao P, Miao XH, Zhao LJ, Xue LJ, Qi Zt Z. Phage display selection on whole cells yields a small peptide specific for HCV receptor human CD81. Cell Res 2003; 13: 473-479.
    • (2003) Cell Res , vol.13 , pp. 473-479
    • Cao, J.1    Zhao, P.2    Miao, X.H.3    Zhao, L.J.4    Xue, L.J.5    Qi Zt, Z.6
  • 23
    • 0035132970 scopus 로고    scopus 로고
    • Binding of the hepatitis C virus envelope protein E2 to CD81 provides a co-stimulatory signal for human T cells
    • Wack A, Soldaini E, Tseng C, Nuti S, Klimpel G, Abrignani S. Binding of the hepatitis C virus envelope protein E2 to CD81 provides a co-stimulatory signal for human T cells. Eur J Immunol 2001; 31: 166-175.
    • (2001) Eur J Immunol , vol.31 , pp. 166-175
    • Wack, A.1    Soldaini, E.2    Tseng, C.3    Nuti, S.4    Klimpel, G.5    Abrignani, S.6
  • 24
    • 33344458030 scopus 로고    scopus 로고
    • T cells use two directionally distinct pathways for cytokine secretion
    • Huse M, Lillemeier BF, Kuhns MS, Chen DS, Davis MM. T cells use two directionally distinct pathways for cytokine secretion. Nat Immunol 2006; 7: 247-255.
    • (2006) Nat Immunol , vol.7 , pp. 247-255
    • Huse, M.1    Lillemeier, B.F.2    Kuhns, M.S.3    Chen, D.S.4    Davis, M.M.5
  • 25
    • 33745876557 scopus 로고    scopus 로고
    • Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses
    • Urbani S, Amadei B, Fisicaro P, Tola D, Orlandini A, Sacchelli L, et al. Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses. HEPATOLOGY 2006; 44: 126-139.
    • (2006) HEPATOLOGY , vol.44 , pp. 126-139
    • Urbani, S.1    Amadei, B.2    Fisicaro, P.3    Tola, D.4    Orlandini, A.5    Sacchelli, L.6
  • 26
    • 0037105567 scopus 로고    scopus 로고
    • Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
    • Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, Hoofnagle JH, et al. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 2002; 169: 3447-3458.
    • (2002) J Immunol , vol.169 , pp. 3447-3458
    • Wedemeyer, H.1    He, X.S.2    Nascimbeni, M.3    Davis, A.R.4    Greenberg, H.B.5    Hoofnagle, J.H.6
  • 27
    • 77951925447 scopus 로고    scopus 로고
    • Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling
    • Radziewicz H, Ibegbu CC, Hon H, Bedard N, Bruneau J, Workowski KA, et al. Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling. J Immunol 2010; 184: 2410-2422.
    • (2010) J Immunol , vol.184 , pp. 2410-2422
    • Radziewicz, H.1    Ibegbu, C.C.2    Hon, H.3    Bedard, N.4    Bruneau, J.5    Workowski, K.A.6
  • 29
    • 34548191951 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction
    • Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol 2007; 81: 9249-9258.
    • (2007) J Virol , vol.81 , pp. 9249-9258
    • Golden-Mason, L.1    Palmer, B.2    Klarquist, J.3    Mengshol, J.A.4    Castelblanco, N.5    Rosen, H.R.6
  • 30
    • 18644370174 scopus 로고    scopus 로고
    • Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help
    • Fuller MJ, Hildeman DA, Sabbaj S, Gaddis DE, Tebo AE, Shang L, et al. Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help. J Immunol 2005; 174: 5926-5930.
    • (2005) J Immunol , vol.174 , pp. 5926-5930
    • Fuller, M.J.1    Hildeman, D.A.2    Sabbaj, S.3    Gaddis, D.E.4    Tebo, A.E.5    Shang, L.6
  • 31
    • 0037221289 scopus 로고    scopus 로고
    • Ablation of CD8 and CD4 T cell responses by high viral loads
    • Fuller MJ, Zajac AJ. Ablation of CD8 and CD4 T cell responses by high viral loads. J Immunol 2003; 170: 477-486.
    • (2003) J Immunol , vol.170 , pp. 477-486
    • Fuller, M.J.1    Zajac, A.J.2
  • 32
    • 0141677716 scopus 로고    scopus 로고
    • Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2
    • Iyasere C, Tilton JC, Johnson AJ, Younes S, Yassine-Diab B, Sekaly RP, et al. Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2. J Virol 2003; 77: 10900-10909.
    • (2003) J Virol , vol.77 , pp. 10900-10909
    • Iyasere, C.1    Tilton, J.C.2    Johnson, A.J.3    Younes, S.4    Yassine-Diab, B.5    Sekaly, R.P.6
  • 33
    • 34250685855 scopus 로고    scopus 로고
    • Analysis of the relationship between cytokine secretion and proliferative capacity in hepatitis C virus infection
    • Semmo N, Krashias G, Willberg C, Klenerman P. Analysis of the relationship between cytokine secretion and proliferative capacity in hepatitis C virus infection. J Viral Hepat 2007; 14: 492-502.
    • (2007) J Viral Hepat , vol.14 , pp. 492-502
    • Semmo, N.1    Krashias, G.2    Willberg, C.3    Klenerman, P.4
  • 34
    • 17244380947 scopus 로고    scopus 로고
    • Lipid rafts and membrane dynamics
    • Rajendran L, Simons K. Lipid rafts and membrane dynamics. J Cell Sci 2005; 118: 1099-1102.
    • (2005) J Cell Sci , vol.118 , pp. 1099-1102
    • Rajendran, L.1    Simons, K.2
  • 35
    • 75549090719 scopus 로고    scopus 로고
    • Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection
    • Crotta S, Brazzoli M, Piccioli D, Valiante NM, Wack A. Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection. J Hepatol 2010; 52: 183-190.
    • (2010) J Hepatol , vol.52 , pp. 183-190
    • Crotta, S.1    Brazzoli, M.2    Piccioli, D.3    Valiante, N.M.4    Wack, A.5
  • 36
    • 33947258860 scopus 로고    scopus 로고
    • Control of local actin assembly by membrane fusion-dependent compartment mixing
    • Yu HY, Bement WM. Control of local actin assembly by membrane fusion-dependent compartment mixing. Nat Cell Biol 2007; 9: 149-159.
    • (2007) Nat Cell Biol , vol.9 , pp. 149-159
    • Yu, H.Y.1    Bement, W.M.2
  • 37
    • 2642557101 scopus 로고    scopus 로고
    • HIV type 1 Nef increases the association of T cell receptor (TCR)-signaling molecules with T cell rafts and promotes activation-induced raft fusion
    • Djordjevic JT, Schibeci SD, Stewart GJ, Williamson P. HIV type 1 Nef increases the association of T cell receptor (TCR)-signaling molecules with T cell rafts and promotes activation-induced raft fusion. AIDS Res Hum Retroviruses 2004; 20: 547-555.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 547-555
    • Djordjevic, J.T.1    Schibeci, S.D.2    Stewart, G.J.3    Williamson, P.4
  • 38
    • 33645995736 scopus 로고    scopus 로고
    • Association of herpesvirus saimiri tip with lipid raft is essential for downregulation of T-cell receptor and CD4 coreceptor
    • Cho NH, Kingston D, Chang H, Kwon EK, Kim JM, Lee JH, et al. Association of herpesvirus saimiri tip with lipid raft is essential for downregulation of T-cell receptor and CD4 coreceptor. J Virol 2006; 80: 108-118.
    • (2006) J Virol , vol.80 , pp. 108-118
    • Cho, N.H.1    Kingston, D.2    Chang, H.3    Kwon, E.K.4    Kim, J.M.5    Lee, J.H.6
  • 39
    • 4143074753 scopus 로고    scopus 로고
    • Measles virus interacts with and alters signal transduction in T-cell lipid rafts
    • Avota E, Muller N, Klett M, Schneider-Schaulies S. Measles virus interacts with and alters signal transduction in T-cell lipid rafts. J Virol 2004; 78: 9552-9559.
    • (2004) J Virol , vol.78 , pp. 9552-9559
    • Avota, E.1    Muller, N.2    Klett, M.3    Schneider-Schaulies, S.4
  • 40
    • 33645106780 scopus 로고    scopus 로고
    • Pilot study of interferon-alpha-ribavirin-interleukin-2 for treatment of nonresponder patients with severe liver disease infected by hepatitis C virus genotype 1
    • Alric L, Thebault S, Peron JM, Balard P, Metivier S, Pipy B, et al. Pilot study of interferon-alpha-ribavirin-interleukin-2 for treatment of nonresponder patients with severe liver disease infected by hepatitis C virus genotype 1. J Viral Hepat 2006; 13: 139-144.
    • (2006) J Viral Hepat , vol.13 , pp. 139-144
    • Alric, L.1    Thebault, S.2    Peron, J.M.3    Balard, P.4    Metivier, S.5    Pipy, B.6
  • 41
    • 13944251642 scopus 로고    scopus 로고
    • Pilot study of low-dose interleukin-2, pegylated interferon-alpha 2b, and ribavirin for the treatment of hepatitis C virus infection in patients with HIV infection
    • Glesby MJ, Bassett R, Alston-Smith B, Fichtenbaum C, Jacobson EL, Brass C, et al. Pilot study of low-dose interleukin-2, pegylated interferon-alpha 2b, and ribavirin for the treatment of hepatitis C virus infection in patients with HIV infection. J Infect Dis 2005; 191: 686-693.
    • (2005) J Infect Dis , vol.191 , pp. 686-693
    • Glesby, M.J.1    Bassett, R.2    Alston-Smith, B.3    Fichtenbaum, C.4    Jacobson, E.L.5    Brass, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.