Mixed influenza A and B infections complicate the detection of influenza viruses with altered sensitivities to neuraminidase inhibitors

Antiviral Research

Volumn 91, Issue 1, 2011, Pages 20-22

  Mohr, Peter G ^a   Geyer, Henriette ^a   McKimm Breschkin, Jennifer L ^a  

^a CSIRO   (Australia)

Author keywords

Influenza A; Influenza B; Mixed infections; Oseltamivir; Zanamivir

Indexed keywords

OSELTAMIVIR; VIRUS SIALIDASE; ZANAMIVIR;

ANIMAL CELL; ANTIVIRAL RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ANTIVIRAL THERAPY; ARTICLE; HUMAN; IC 50; INFLUENZA A (H3N2); INFLUENZA B; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS B; MIXED INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGENY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROLOGY; VIRUS DETECTION; VIRUS ISOLATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOGS; DRUG RESISTANCE, VIRAL; ENZYME INHIBITORS; HUMANS; INFLUENZA A VIRUS, H2N2 SUBTYPE; INFLUENZA B VIRUS; INFLUENZA, HUMAN; NEURAMINIDASE; OSELTAMIVIR; ZANAMIVIR;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 79957501655     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2011.04.010     Document Type: Article

References (10)

1. Bao Y., Bolotov P., Dernovoy D., Kiryutin B., Zaslavsky L., Tatusova T., Ostell J., Lipman D. The influenza virus resource at the National Center for Biotechnology information. J. Virol. 2008, 82:596-601.
2. Falchi A., Arena C., Andreoletti L., Jacques J., Leveque N., Blanchon T., Lina B., Turbelin C., Dorléans Y., Flahault A., Amoros J.P., Spadoni G., Agostini F., Varesi L. Dual infections by influenza A/H3N2 and B viruses and by influenza A/H3N2 and A/H1N1 viruses during winter 2007, Corsica Island. France. J. Clin. Virol. 2008, 41:148-151.
3. Ghedin E., Fitch A., Boyne A., Griesemer S., DePasse J., Bera J., Zhang X., Halpin R.A., Smit M., Jennings L., St.George K., Holmes E.C., Spiro D.J. Mixed infection and the genesis of influenza virus diversity. J. Virol. 2009, 83:8832-8841.
4. Hurt A.C., Iannello P., Jachno K., Komadina N., Hampson A.W., Barr I.G., McKimm-Breschkin J.L. Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient. Antimicrob. Agents Chemother. 2006, 50:1872-1874.
5. Lin Y.P., Gregory V., Collins P., Kloess J., Wharton S., Cattle N., Lackenby A., Daniels R., Hay A. Neuraminidase receptor binding variants of human influenza A(H3N2) viruses resulting from substitution of aspartic acid 151 in the catalytic site: a role in virus attachment?. J. Virol. 2010, 84:6769-6781.
6. McKimm-Breschkin J.L., Blick T.J., Sahasrabudhe A., Tiong T., Marshall D., Hart G.J., Bethell R.C., Penn C.R. Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en. Antimicrob. Agents Chemother. 1996, 40:40-46.
7. McKimm-Breschkin J., Trivedi T., Hampson A., Hay A., Klimov A., Tashiro M., Hayden F., Zambon M. Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir. Antimicrob. Agents Chemother. 2003, 47:2264-2272.
8. Monto A.S., McKimm-Breschkin J.L., Macken C., Hampson A.W., Hay A., Klimov A., Tashiro M., Webster R.G., Aymard M., Hayden F.G., Zambon M. Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3years of their use. Antimicrob. Agents Chemother. 2006, 50:2395-2401.
9. Tashiro M., McKimm-Breschkin J.L., Saito T., Klimov A., Macken C., Zambon M., Hayden F.G. Surveillance for neuraminidase inhibitor-resistant influenza viruses in Japan, 1996-2007. Antivir. Ther. 2009, 14:751-761.
10. Wetherall N.T., Trivedi T., Zeller J., Hodges-Savola C., McKimm-Breschkin J.L., Zambon M., Hayden F.G. Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network. J. Clin. Microbiol. 2003, 41:742-750.