메뉴 건너뛰기




Volumn 6, Issue 5, 2011, Pages 452-465

Identification and optimization of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; HISTONE H4; INTEGRIN; MESSENGER RNA; NOTCH RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN;

EID: 79957498341     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb100305h     Document Type: Conference Paper
Times cited : (31)

References (28)
  • 1
    • 0033079605 scopus 로고    scopus 로고
    • The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
    • DOI 10.1016/S0968-0004(98)01343-7, PII S0968000498013437
    • Christofori, G. and Semb, H. (1999) The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene Trends Biochem. Sci. 24 (2) 73-76 (Pubitemid 29346577)
    • (1999) Trends in Biochemical Sciences , vol.24 , Issue.2 , pp. 73-76
    • Christofori, G.1    Semb, H.2
  • 2
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
    • Cavallaro, U. and Christofori, G. (2004) Cell adhesion and signalling by cadherins and Ig-CAMs in cancer Nat. Rev. Cancer 4 (2) 118-132 (Pubitemid 38198740)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2
  • 3
    • 0037264812 scopus 로고    scopus 로고
    • Metastasis suppressors alter the signal transduction of cancer cells
    • DOI 10.1038/nrc967
    • Steeg, P. S. (2003) Metastasis suppressors alter the signal transduction of cancer cells Nat. Rev. Cancer 3 (1) 55-63 (Pubitemid 37328887)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.1 , pp. 55-63
    • Steeg, P.S.1
  • 4
    • 39849084350 scopus 로고    scopus 로고
    • Structural and functional associations of apical junctions with cytoskeleton
    • Miyoshi, J. and Takai, Y. (2008) Structural and functional associations of apical junctions with cytoskeleton Biochim. Biophys. Acta 1778 (3) 670-691
    • (2008) Biochim. Biophys. Acta , vol.1778 , Issue.3 , pp. 670-691
    • Miyoshi, J.1    Takai, Y.2
  • 5
    • 70349165716 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic
    • Voulgari, A. and Pintzas, A. (2009) Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic Biochim. Biophys. Acta 1796 (2) 75-90
    • (2009) Biochim. Biophys. Acta , vol.1796 , Issue.2 , pp. 75-90
    • Voulgari, A.1    Pintzas, A.2
  • 9
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra, K. M., Chen, D. Y., and Fearon, E. R. (2002) The SLUG zinc-finger protein represses E-cadherin in breast cancer Cancer Res. 62 (6) 1613-1618 (Pubitemid 34408479)
    • (2002) Cancer Research , vol.62 , Issue.6 , pp. 1613-1618
    • Hajra, K.M.1    David, Y.-S.2    Fearon, E.R.3
  • 10
    • 0035920152 scopus 로고    scopus 로고
    • A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
    • Perez-Moreno, M. A., Locascio, A., Rodrigo, I., Dhondt, G., Portillo, F., Nieto, M. A., and Cano, A. (2001) A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions J. Biol. Chem. 276 (29) 27424-27431
    • (2001) J. Biol. Chem. , vol.276 , Issue.29 , pp. 27424-27431
    • Perez-Moreno, M.A.1    Locascio, A.2    Rodrigo, I.3    Dhondt, G.4    Portillo, F.5    Nieto, M.A.6    Cano, A.7
  • 11
    • 0029083459 scopus 로고
    • Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo
    • Hennig, G., Behrens, J., Truss, M., Frisch, S., Reichmann, E., and Birchmeier, W. (1995) Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo Oncogene 11 (3) 475-484
    • (1995) Oncogene , vol.11 , Issue.3 , pp. 475-484
    • Hennig, G.1    Behrens, J.2    Truss, M.3    Frisch, S.4    Reichmann, E.5    Birchmeier, W.6
  • 13
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • Yoo, C. B. and Jones, P. A. (2006) Epigenetic therapy of cancer: past, present and future Nat. Rev. Drug Discovery 5 (1) 37-50
    • (2006) Nat. Rev. Drug Discovery , vol.5 , Issue.1 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 16
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • Onder, T. T., Gupta, P. B., Mani, S. A., Yang, J., Lander, E. S., and Weinberg, R. A. (2008) Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways Cancer Res. 68 (10) 3645-3654
    • (2008) Cancer Res. , vol.68 , Issue.10 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 17
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • DOI 10.1038/32433
    • Perl, A. K., Wilgenbus, P., Dahl, U., Semb, H., and Christofoti, G. (1998) A causal role for E-cadherin in the transition from adenoma to carcinoma Nature 392 (6672) 190-193 (Pubitemid 28162793)
    • (1998) Nature , vol.392 , Issue.6672 , pp. 190-193
    • Peri, A.-K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 18
    • 0025818032 scopus 로고
    • Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
    • Vleminckx, K., Vakaet, L., Jr., Mareel, M., Fiers, W., and von Roy, F. (1991) Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role Cell 66 (1) 107-119 (Pubitemid 121001351)
    • (1991) Cell , vol.66 , Issue.1 , pp. 107-119
    • Vleminckx, K.1    Vakaet Jr., L.2    Mareel, M.3    Fiers, W.4    Van Roy, F.5
  • 19
    • 0028245813 scopus 로고
    • Cadherin expression in carcinomas: Role in the formation of cell junctions and the prevention of invasiveness
    • DOI 10.1016/0304-419X(94)90003-5
    • Birchmeier, W. and Behrens, J. (1994) Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness Biochim. Biophys. Acta 1198 (1) 11-26 (Pubitemid 24159061)
    • (1994) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1198 , Issue.1 , pp. 11-26
    • Birchmeier, W.1    Behrens, J.2
  • 20
    • 0031830664 scopus 로고    scopus 로고
    • Inactivation of the E-cadherin-mediated cell adhesion system in human cancers
    • Hirohashi, S. (1998) Inactivation of the E-cadherin-mediated cell adhesion system in human cancers Am. J. Pathol. 153 (2) 333-9 (Pubitemid 28373643)
    • (1998) American Journal of Pathology , vol.153 , Issue.2 , pp. 333-339
    • Hirohashi, S.1
  • 21
    • 57349114162 scopus 로고    scopus 로고
    • The cell-cell adhesion molecule E-cadherin
    • van Roy, F. and Berx, G. (2008) The cell-cell adhesion molecule E-cadherin Cell. Mol. Life Sci. 65 (23) 3756-3788
    • (2008) Cell. Mol. Life Sci. , vol.65 , Issue.23 , pp. 3756-3788
    • Van Roy, F.1    Berx, G.2
  • 23
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • DOI 10.1242/jcs.00224
    • Bolos, V., Peinado, H., Perez-Moreno, M. A., Fraga, M. F., Esteller, M., and Cano, A. (2003) The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors J. Cell Sci. 116 (Pt 3) 499-511 (Pubitemid 36231290)
    • (2003) Journal of Cell Science , vol.116 , Issue.3 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 27
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • DOI 10.1177/108705719900400206
    • Zhang, J. H., Chung, T. D., and Oldenburg, K. R. (1999) A simple statistical parameter for use in evaluation and validation of high throughput screening assays J. Biomol. Screening 4 (2) 67-73 (Pubitemid 29278954)
    • (1999) Journal of Biomolecular Screening , vol.4 , Issue.2 , pp. 67-73
    • Zhang, J.-H.1    Chung, T.D.Y.2    Oldenburg, K.R.3
  • 28
    • 0028347883 scopus 로고
    • The loss of E-cadherin mRNA transcripts in rat prostatic tumors is accompanied by increased expression of mRNA transcripts encoding fibronectin and its receptor
    • MacCalman, C. D., Brodt, P., Doublet, J. D., Jednak, R., Elhilali, M. M., Bazinet, M., and Blaschuk, O. W. (1994) The loss of E-cadherin mRNA transcripts in rat prostatic tumors is accompanied by increased expression of mRNA transcripts encoding fibronectin and its receptor Clin. Exp. Metastasis 12 (2) 101-107 (Pubitemid 24126569)
    • (1994) Clinical and Experimental Metastasis , vol.12 , Issue.2 , pp. 101-107
    • MacCalman, C.D.1    Brodt, P.2    Doublet, J.D.3    Jednak, R.4    Elhilali, M.M.5    Bazinet, M.6    Blaschuk, O.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.