In-process monitoring and control of supersaturation in seeded batch cooling crystallisation of l-glutamic acid: From laboratory to industrial pilot plant

Organic Process Research and Development

Volumn 15, Issue 3, 2011, Pages 540-555

  Khan, Shahid ^a   Ma, Cai Y ^a   Mahmud, Tariq ^a   Penchev, Radoslav Y ^a   Roberts, Kevin J ^a   Morris, Julian ^b   Özkan, Leyla ^b   White, Graeme ^c   Grieve, Bruce ^d   Hall, Alan ^d   Buser, Paul ^e   Gibson, Neil ^e   Keller, Patrik ^e   Shuttleworth, Paul ^f   Price, Christopher J ^g  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c HERIOT WATT UNIVERSITY   (United Kingdom)

^d JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

^e SYNGENTA CROP PROTECTION AG   (Switzerland)

^f HEL Ltd   (United Kingdom)

^g GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AQUEOUS SOLUTIONS; ATR-FT-IR SPECTROSCOPY; BATCH COOLING; CHEMOMETRICES; CONTROL EXPERIMENTS; COOLING RATES; CRYSTALLISATION; IN-PROCESS; IN-PROCESS MONITORING; L-GLUTAMIC ACIDS; LABORATORY EXPERIMENTS; MEAN COOLING; MEASUREMENT-BASED; MONITORING AND CONTROL; PLS CALIBRATION; PRODUCT CRYSTALS; SCALE SIZES; SECONDARY NUCLEATION; SWITZERLAND; SYNGENTA;

AMINO ACIDS; CHROMOPHORES; COOLING; CRYSTALLIZATION; EXPERIMENTS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; INDUSTRY; PILOT PLANTS; PROCESS MONITORING; SUPERSATURATION;

PROCESS CONTROL;

EID: 79957496942     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op100223a     Document Type: Article

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