Guttiferones Q-S, cytotoxic polyisoprenylated benzophenones from the pericarp of Garcinia cochinchinensis

Phytochemistry Letters

Volumn 4, Issue 2, 2011, Pages 129-133

  Nguyen, Hiep D ^a   Trinh, Binh T D ^a   Nguyen, Lien Hoa D ^a  

^a UNIVERSITY OF NATURAL SCIENCES   (Viet Nam)

Author keywords

Cytotoxicity; Garcinia cochinchinensis; Guttiferae; Guttiferones Q S; Structure elucidation; Xanthones

Indexed keywords

1,3 DIHYDROXY 5,6 DIMETHOXY 7 (3 METHYL BUT 2 ENYL)XANTHONE; 1,3,5 TRIHYDROXY 13,13 DIMETHYL 2H PYRAN[7,6-B]XANTHEN 9 ONE; 1,3,5 TRIHYDROXY 6 METHOXY 7 (3 METHYLBUT 2 ENYL)XANTHONE; BENZOPHENONE DERIVATIVE; CITRIC ACID; DULXANTHONE A; GUTTIFERONE I; GUTTIFERONE Q; GUTTIFERONE R; GUTTIFERONE S; TRIMETHYL CITRATE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; CELL STRAIN NCI H460; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; GARCINIA; GARCINIA COCHINCHINENSIS; HELA CELL; HUMAN; HUMAN CELL; IC 50; ISOPRENYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PERICARP; PRIORITY JOURNAL; VIET NAM;

CLUSIACEAE; GARCINIA;

EID: 79957472827     PISSN: 18743900     EISSN: 18767486     Source Type: Journal    
DOI: 10.1016/j.phytol.2011.01.001     Document Type: Article

References (16)

1. S. Baggett, P. Provita, E.P. Mazzola, H. Yang, E.T. Ressler, M.J. Basile, I.B. Weinstein, and E.J. Kennelly Bioactive benzophenones from Garcinia xanthochymus fruits J. Nat. Prod. 68 2005 354 360 (Pubitemid 40545470)
2. C. Gey, S. Kyrylenko, L. Hennig, L.H.D. Nguyen, A. Büttner, H.D. Pham, and A. Giannis Phloroglucinol derivatives guttiferone G, aristoforin, and hyperforin: inhibitors of human sirtuins SIRT1 and SIRT2 Angew. Chem. Int. Ed. 46 2007 5219 5222 (Pubitemid 47051294)
3. K.R. Gustafson, J.W. Blunt, H.G.M. Munro, R.W. Fuller, C.T. McKee, J.H. Cardellina, J.B. McMahon, G.M. Cragg, and M.R. Boyd The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea Tetrahedron 48 1992 10093 10102
4. W. Hamed, S. Brajeul, F. Mahuteau-Betzer, O. Thoison, S. Mons, B. Delpech, V. Nguyen, Hung, T. Sévenet, and C. Marazano Oblongifolins A-D, polyprenylated benzoylphloroglucinol derivatives from Garcinia oblongifolia J. Nat. Prod. 69 2006 774 777 (Pubitemid 44021403)
5. Q.-B. Han, H.-L. Tian, N.-Y. Yang, C.-F. Qiao, J.-Z. Song, D.C. Chang, K.Q. Luo, and H.-X. Xu Polyprenylated xanthones from Garcinia lancilimba showing apoptotic effects against HeLa-C3 cells Chem. Biodivers. 5 2008 2710 2717
6. Y.N. Han, Y. Choo, Y.-C. Lee, Y.-I. Moon, S.-D. Kim, and J.-W. Choi Monoamine oxidase B inhibitors from the fruits of Opuntia ficus-indica var. saboten Arch. Pharm. Res. 24 1 2001 51 54 (Pubitemid 33647247)
7. C. Ito, Y. Miyamoto, M. Nakayama, Y. Kawai, S.K. Rao, and H. Furukawa A novel depsidone and some new xanthones from Garcinia species Chem. Pharm. Bull. 45 1997 1403 1413 (Pubitemid 27431030)
8. C. Ito, M. Itoigawa, Y. Miyamoto, S. Onoda, K.S. Rao, T. Mukainaka, H. Tokuda, H. Nishino, and H. Furukawa Polyprenylated benzophenones from Garcinia assigu and their potential cancer chemopreventive activities J. Nat. Prod. 66 2003 206 209 (Pubitemid 36278230)
9. J. Lokvam, J.F. Braddock, P.B. Reichardt, and T.P. Clausen Two polyisoprenylated benzophenones from the trunk latex of Clusia grandiflora (Clusiaceae) Phytochemistry 55 2000 29 34
10. J.J. Magadula, C.M. Kapingu, M. Bezabih, and M.B. Abegaz Polyisoprenylated benzophenones from Garcinia semseii (Clusiaceae) Phytochem. Lett. 1 2008 215 218
11. K. Matsumoto, Y. Akao, E. Kobayashi, T. Ito, K. Ohguchi, T. Tanaka, M. Iinuma, and Y. Nozawa Cytotoxic benzophenone derivatives from Garcinia species display a strong apoptosis-including effect against human Leukemia cell lines Biol. Pharm. Bull. 26 4 2003 569 571
12. J. Merza, S. Mallet, M. Litaudon, V. Dumontet, D. Sépharin, and P. Richomme New cytotoxic guttiferone analogues from Garcinia virgata from New Caledonia Planta Med. 72 2006 87 89 (Pubitemid 43241602)
13. Nilar, D.L.-H. Nguyen, G. Venkatraman, K.-Y. Sim, and L.J. Harrison Xanthones and benzophenones from Garcinia griffithii and G. mangostana Phytochemistry 66 14 2005 1718 1723 (Pubitemid 41026627)
14. S. Sang, C.-H. Liao, M.-H. Pan, T.R. Rosen, S.-Y. Lin-Shiau, J.-K. Lin, and C.-T. Ho Chemical studies on antioxidant mechanism of garcinol: analysis of radical reaction products of garcinol with peroxyl radicals and their antitumor activities Tetrahedron 58 2002 10095 10102 (Pubitemid 35447793)
15. P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J.T. Warren, H. Bokesch, S. Kenney, and M.R. Boyd J. Natl. Cancer Inst. 82 1990 1107 1112
16. V.C. Vo Dictionary of Vietnamese Medicinal Plants 1997 Medical Publisher Ho Chi Minh City