Anti-proliferative activity of aguerin B and a new rare nor-guaianolide lactone isolated from the aerial parts of Centaurea deflexa

European Journal of Medicinal Chemistry

Volumn 46, Issue 7, 2011, Pages 3066-3070

  Chicca, Andrea ^a,c   Tebano, Marianna ^a   Adinolfi, Barbara ^a   Ertugrul, Kuddisi ^b   Flamini, Guido ^a   Nieri, Paola ^a  

^a UNIVERSITY OF PISA   (Italy)

^b SELCUK UNIVERSITY   (Turkey)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Anti proliferative; Apoptosis; Asteraceae; Centaurea; Guaianolide; Sesquiterpene lactone

Indexed keywords

15 NOR GUAIANOLIDE; AGUERIN B; ALKALOID DERIVATIVE; ANTINEOPLASTIC AGENT; FLAVONOID; FLUOROURACIL; LIGNAN; PHENOL DERIVATIVE; PHENYLPROPANOID DERIVATIVE; SESQUITERPENE LACTONE DERIVATIVE; STEROL; UNCLASSIFIED DRUG; LACTONE; PLANT EXTRACT; SESQUITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTERACEAE; CANCER CELL; CELL PROLIFERATION; CENTAUREA DEFLEXA; COLON CANCER; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; MICHAEL ADDITION; PANCREAS CANCER; PHYTOCHEMISTRY; CENTAUREA; CHEMISTRY; DNA FRAGMENTATION; DRUG EFFECTS; ISOLATION AND PURIFICATION; PLANT; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CENTAUREA; DNA FRAGMENTATION; HUMANS; LACTONES; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; SESQUITERPENES; SESQUITERPENES, GUAIANE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79957455045     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.03.011     Document Type: Article

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