Sensitive quantification of diclofenac and ibuprofen using thin layer chromatography coupled with a vibrio fisheri bioluminescence assay

Journal of Liquid Chromatography and Related Technologies

Volumn 34, Issue 10-11, 2011, Pages 817-828

  Seigel, Andrea ^a   Schröck, Alexandra ^a   Hauser, Rebekka ^a   Spangenberg, Bernd ^a  

^a OFFENBURG UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

bioeffective linked analysis; diclofenac; HPTLC; ibuprofen; Kubelka Munk equation; linear calibration range; quantification; TLC; Vibrio fisheri; video densitometry

Indexed keywords

BIOEFFECTIVE-LINKED ANALYSIS; DICLOFENAC; HPTLC; IBUPROFEN; KUBELKA-MUNK EQUATION; LINEAR CALIBRATION; QUANTIFICATION; TLC; VIBRIO FISHERI; VIDEO DENSITOMETRY;

BACTERIA; BACTERIOLOGY; BIOLUMINESCENCE; CHROMATOGRAPHIC ANALYSIS; LIGHT EMISSION; LINEAR TRANSFORMATIONS; METADATA; METHANOL; THIN LAYER CHROMATOGRAPHY;

CCD CAMERAS;

CYCLOHEXANE; DICLOFENAC; IBUPROFEN; METHANOL; METHYL CHLORIDE;

ARTICLE; BIOLUMINESCENCE; DRUG DETERMINATION; MEASUREMENT; NONHUMAN; QUANTITATIVE ANALYSIS; RELIABILITY; SENSITIVITY AND SPECIFICITY; THIN LAYER CHROMATOGRAPHY; VIBRIO FISCHERI; WHITE LIGHT;

BACTERIA (MICROORGANISMS); VIBRIO FISCHERI;

EID: 79957453708     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2011.571149     Document Type: Article

References (9)

1. Cleuvers, M. Mixture Toxicity of the Anti-Inflammatory Drugs Diclofenac, Ibuprofen, Naproxen, and Acetylsalicylic Acid. Ecotoxicol. Environ. Saf. 2004, 59, 309-315. (Pubitemid 39243972)
2. Dietrich, D. R; Webb, S. F.; Petry, T.; Kümmerer, K., Eds. Hot Spot Pollutants: Pharmaceuticals in the Environment, Academic Press, Elsevier: Amsterdam, 2005.
3. Kümmerer, K., Ed. Pharmaceuticals in the Environment: Sources, Fate, Effects and Risks, 2nd Ed.; Springer: Berlin, Heidelberg, New York, 2004.
4. Loeffler, D.; Roempke, J.; Meller, M.; Ternes, Th. A. Environmental Fate of Pharmaceuticals in Water/Sediment Systems. Environ. Sci. Technol. 2005, 39, 5209-5218. (Pubitemid 41003738)
5. Sajewicz, M. Use of Densitometric TLC for Detection of Selected Drugs Present in River Water in South Poland.J. Planar Chromatogr. 2005, 18, 108-111. (Pubitemid 40796825)
6. Oaks, J. L.; Gilbert, M.; Virani, M. Z.; Watson, R. T.; Meteyer, C U.; Rideout, B. A.; Shivaprasad, H. L.; Ahmed, S.; Chaudhry, M. J.; Arshad, M.; Mahmood, S.; Ali, A.; Khan, A. A. Diclofenac Residues as the Cause of Vulture Population Decline in Pakistan. Nature 2004, 427, 630-633. (Pubitemid 38248481)
7. Broszat, M.; Ernst, H.; Spangenberg, B. A Simple Method for Quantifying Triazine Herbicides Using Thin-Layer Chromatography and a CCD Camera. JLC&RT 2010, 33, 948-956.
8. Spangenberg, B. Does the Kubelka-Munk Theory Describe TLC Evaluations Correctly? J. Planar Chromatogr. 2006, 19, 332-341. (Pubitemid 44741733)
9. Funk, W.; Dammann, V.; Donnevert, G. Quality Assurance in Analytical Chemistry, 2nd Ed.; WILEY-VCH: Weinheim, 2007.