Cytotoxic and antioxidant property of a purified fraction (NN-32) of Indian Naja naja venom on Ehrlich ascites carcinoma in BALB/c mice

Toxicon

Volumn 57, Issue 7-8, 2011, Pages 1065-1072

  Das, Tanaya ^a   Bhattacharya, Shamik ^a   Halder, Babli ^a   Biswas, Archita ^a   Das Gupta, Shubho ^a   Gomes, Antony ^b   Gomes, Aparna ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b UNIVERSITY OF CALCUTTA   (India)

Author keywords

Anticancer property; Antioxidant system; Apoptosis; Ehrlich ascites carcinoma; Naja naja; Snake venom

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; CARDIOTOXIN; CASPASE 3; CASPASE 9; CYTOTOXIN; FLUOROURACIL; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; INTERLEUKIN 10; KERATINOCYTE DERIVED CHEMOKINE; NN 32 PROTEIN; PROTEIN BAX; PROTEIN BCL 2; SNAKE VENOM; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOTOXICITY; CELL COUNT; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG PURIFICATION; EHRLICH ASCITES TUMOR; ENZYME ACTIVITY; FRACTIONATION; GUINEA PIG; HEART CONTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; NAJA NAJA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SNAKE; SURVIVAL TIME; TUMOR VOLUME; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CARCINOMA, EHRLICH TUMOR; COBRA VENOMS; CYTOTOXINS; GUINEA PIGS; MALE; MICE; MICE, INBRED BALB C; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

CAVIA; MURINAE; MUS; NAJA; NAJA NAJA;

EID: 79956338550     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2011.04.012     Document Type: Article

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