A perfusion-independent role of blood vessels in determining branching stereotypy of lung airways

Development

Volumn 138, Issue 11, 2011, Pages 2359-2368

  Lazarus, Alon ^a   Del Moral, Pierre Marie ^b   Ilovich, Ohad ^c   Mishani, Eyal ^c   Warburton, David ^b   Keshet, Eli ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Branching morphogenesis; Lung development; Mouse; Vascular network

Indexed keywords

AIRWAY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CONTROLLED STUDY; EXPLANT; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG BLOOD VESSEL; LUNG PERFUSION; MOUSE; NONHUMAN; ORGAN SIZE; PRIORITY JOURNAL; VASCULARIZATION;

ANIMALS; CELL COMMUNICATION; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 10; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; IN SITU HYBRIDIZATION; LUNG; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; MORPHOGENESIS; NEOVASCULARIZATION, PHYSIOLOGIC; ORGAN CULTURE TECHNIQUES; ORGANOGENESIS; POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79956320721     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.060723     Document Type: Article

References (26)

1. Akeson, A. L., Greenberg, J. M., Cameron, J. E., Thompson, F. Y., Brooks, S. K., Wiginton, D. and Whitsett, J. A. (2003). Temporal and spatial regulation of VEGF-A controls vascular patterning in the embryonic lung. Dev. Biol. 264, 443-455.
2. Bellusci, S., Grindley, J., Emoto, H., Itoh, N. and Hogan, B. L. (1997). Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124, 4867-4878.
3. Cardoso, W. V. and Lu, J. (2006). Regulation of early lung morphogenesis: questions, facts and controversies. Development 133, 1611-1624.
4. Clark, J. C., Tichelaar, J. W., Wert, S. E., Itoh, N., Perl, A. K., Stahlman, M. T. and Whitsett, J. A. (2001). FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo. Am. J. Physiol. Lung Cell. Mol. Physiol. 280, L705-L715.
5. Cleaver, O. and Melton, D. A. (2003). Endothelial signaling during development. Nat. Med. 9, 661-668.
6. Del Moral, P. M., Sala, F. G., Tefft, D., Shi, W., Keshet, E., Bellusci, S. and Warburton, D. (2006). VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis. Dev. Biol. 290, 177-188.
7. Groenman, F. A., Rutter, M., Wang, J., Caniggia, I., Tibboel, D. and Post, M. (2007). Effect of chemical stabilizers of hypoxia-inducible factors on early lung development. Am. J. Physiol. Lung Cell. Mol. Physiol. 293, L557-L567.
8. Grunewald, M., Avraham, I., Dor, Y., Bachar-Lustig, E., Itin, A., Jung, S., Chimenti, S., Landsman, L., Abramovitch, R. and Keshet, E. (2006). VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell 124, 175-189.
9. Hogan, B. L. (1999). Morphogenesis. Cell 96, 225-233.
10. Hogan, B. L. and Yingling, J. M. (1998). Epithelial/mesenchymal interactions and branching morphogenesis of the lung. Curr. Opin. Genet. Dev. 8, 481-486.
11. Kubo, K., Shimizu, T., Ohyama, S., Murooka, H., Iwai, A., Nakamura, K., Hasegawa, K., Kobayashi, Y., Takahashi, N., Takahashi, K. et al. (2005). Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas. J. Med. Chem. 48, 1359-1366.
12. Lammert, E., Cleaver, O. and Melton, D. (2001). Induction of pancreatic differentiation by signals from blood vessels. Science 294, 564-567.
13. Lu, P. and Werb, Z. (2008). Patterning mechanisms of branched organs. Science 322, 1506-1509.
14. Maeda, Y., Dave, V. and Whitsett, J. A. (2007). Transcriptional control of lung morphogenesis. Physiol. Rev. 87, 219-244.
15. Matsumoto, K., Yoshitomi, H., Rossant, J. and Zaret, K. S. (2001). Liver organogenesis promoted by endothelial cells prior to vascular function. Science 294, 559-563.
16. May, D., Gilon, D., Djonov, V., Itin, A., Lazarus, A., Gordon, O., Rosenberger, C. and Keshet, E. (2008). Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation. Proc. Natl. Acad. Sci. USA 105, 282-287.
17. Metzger, R. J., Klein, O. D., Martin, G. R. and Krasnow, M. A. (2008). The branching programme of mouse lung development. Nature 453, 745-750.
18. Pepicelli, C. V., Lewis, P. M. and McMahon, A. P. (1998). Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr. Biol. 8, 1083-1086.
19. Perl, A. K., Tichelaar, J. W. and Whitsett, J. A. (2002). Conditional gene expression in the respiratory epithelium of the mouse. Transgenic Res. 11, 21-29.
20. Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L. and Schuh, A. C. (1995). Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66.
21. Stanger, B. Z., Tanaka, A. J. and Melton, D. A. (2007). Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver. Nature 445, 886-891.
22. van Tuyl, M., Liu, J., Wang, J., Kuliszewski, M., Tibboel, D. and Post, M. (2005). Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 288, L167-L178.
23. Warburton, D., Bellusci, S., De Langhe, S., Del Moral, P. M., Fleury, V., Mailleux, A., Tefft, D., Unbekandt, M., Wang, K. and Shi, W. (2005). Molecular mechanisms of early lung specification and branching morphogenesis. Pediatr. Res. 57, 26R-37R.
24. Winnier, G., Blessing, M., Labosky, P. A. and Hogan, B. L. (1995). Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9, 2105-2116.
25. Yamamoto, H., Yun, E. J., Gerber, H. P., Ferrara, N., Whitsett, J. A. and Vu, T. H. (2007). Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis. Dev. Biol. 308, 44-53.
26. Yu, K., Xu, J., Liu, Z., Sosic, D., Shao, J., Olson, E. N., Towler, D. A. and Ornitz, D. M. (2003). Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130, 3063-3074.