Hes1 is required for contact inhibition of cell proliferation in 3T3-L1 preadipocytes

Genes to Cells

Volumn 16, Issue 6, 2011, Pages 704-713

  Noda, Natsumi ^a   Honma, Sato ^a   Ohmiya, Yoshihiro ^a,b  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A2; CYCLIN D1; CYCLIN E1; CYCLINE; MYC PROTEIN; NOTCH RECEPTOR; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTACT INHIBITION; CONTROLLED STUDY; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE;

3T3-L1 CELLS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTACT INHIBITION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DIPEPTIDES; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; MICE; MODELS, BIOLOGICAL; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 79956302762     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2011.01518.x     Document Type: Article

References (40)

1. Cip1 promotes cyclin D1 nuclear accumulation via direct inhibition of nuclear export. J. Biol. Chem. 277, 8517-8523.
2. Artavanis-Tsakonas, S., Rand, M.D. & Lake, R.J. (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770-776.
3. Baladrón, V., Ruiz-Hidalgo, M.J., Nueda, M.L., Díaz-Guerra, M.J.M., García-Ramírez, J.J., Bonvini, E., Gubina, E. & Laborda, J. (2005) dlk acts as a negative regulator of Notch1 activation through interactions with specific EGF-like repeats. Exp. Cell Res. 303, 343-359.
4. Castella, P., Sawai, S., Nakao, K., Wagner, J.A. & Caudy, M. (2000) HES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression. Mol. Cell. Biol. 20, 6170-6183.
5. Kip1 CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18, 1571-1583.
6. Cobrinik, D. (2005) Pocket proteins and cell cycle control. Oncogene 24, 2796-2809.
7. Fisher, H.W. & Yeh, J. (1967) Contact inhibition in colony formation. Science 155, 581-582.
8. Green, H. & Kehinde, O. (1974) Sublines of mouse 3T3 cells that accumulate lipid. Cell 1, 113-116.
9. Green, H. & Kehinde, O. (1975) An established preadipose cell line and its differentiation in culture ΙΙ. Factors affecting the adipose conversion. Cell 5, 19-27.
10. Hartman, J., Müller, P., Foster, J.S., Wimalasena, J., Gustafsson, J.-Å. & Ström, A. (2004) HES-1 inhibits 17β-estradiol and heregulin-β1-mediated upregulation of E2F-1. Oncogene 23, 8826-8833.
11. Holley, R.W. & Kiernan, J.A. (1968) ''Contact inhibition'' of cell division in 3T3 cells. Proc. Natl Acad. Sci. USA 60, 300-304.
12. Hsiao, K.-M., McMahon, S.L. & Farnham, P.J. (1994) Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev. 8, 1526-1537.
13. Ingram, W.J., McCue, K.I., Tran, T.H., Hallahan, A.R. & Wainwright, B.J. (2008) Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signaling. Oncogene 27, 1489-1500.
14. Iso, T., Sartorelli, V., Poizat, C., Iezzi, S., Wu, H.-Y., Chung, G., Kedes, L. & Hamamori, Y. (2001) HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling. Mol. Cell. Biol. 21, 6080-6089.
15. Jansen-Dürr, P., Meichle, A., Steiner, P., Pagano, M., Finke, K., Botz, J., Wessbecher, J., Draetta, G. & Eilers, M. (1993) Differential modulation of cyclin gene expression by MYC. Proc. Natl Acad. Sci. USA 90, 3685-3689.
16. Kip2 expression. Mol. Cell. Biol. 27, 7236-7247.
17. Johnson, D.G., Ohtani, K. & Nevins, J.R. (1994) Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev. 8, 1514-1525.
18. Kinkade, R., Dasgupta, P., Carie, A., Pernazza, D., Carless, M., Pillai, S., Lawrence, N., Sebti, S.M. & Chellappan, S. (2008) A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice. Cancer Res. 68, 3810-3818.
19. Levine, E.M., Becker, Y., Boone, C.W. & Eagle, H. (1965) Contact inhibition, macromolecular synthesis, and polyribosomes in cultured human diploid fibroblasts. Proc. Natl Acad. Sci. USA 53, 350-356.
20. Lukas, J., Herzinger, T., Hansen, K., Moroni, M.C., Resnitzky, D., Helin, K., Reed, S.I. & Bartek, J. (1997) Cyclin E-induced S phase without activation of the pRb/E2F pathway. Genes Dev. 11, 1479-1492.
21. Matsumura, I., Tanaka, H. & Kanakura, Y. (2003) E2F1 and c-Myc in cell growth and death. Cell cycle 2, 333-338.
22. Kip1. Mol. Cell. Biol. 25, 4262-4271.
23. Cip1 repression. Mol. Cell. Biol. 24, 8813-8822.
24. 0 cells. Science 296, 1132-1136.
25. Qi, Y., Tu, Y., Yang, D., Chen, Q., Xiao, J., Chen, Y., Fu, J., Xiao, X. & Zhou, Z. (2007) Cyclin A but not Cyclin D1 is essential for c-myc-modulated cell-cycle progression. J. Cell. Physiol. 210, 63-71.
26. Rangarajan, A., Talora, C., Okuyama, R., Nicolas, M., Mammucari, C., Oh, H., Aster, J.C., Krishna, S., Metzger, D., Chambon, P., Miele, L., Aguet, M., Radtke, F. & Dotto, G.P. (2001) Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 20, 3427-3436.
27. Kip1. Mol. Cell. Biol. 15, 4347-4352.
28. Kip2. EMBO Rep. 9, 377-383.
29. ic. Mol. Cell. Biol. 21, 5925-5934.
30. Ross, D.A., Rao, P.K. & Kadesch, T. (2004) Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes. Mol. Cell. Biol. 24, 3505-3513.
31. Sang, L., Coller, H.A. & Roberts, J.M. (2008) Control of the reversibility of cellular quiescence by the transcriptional repressor HES1. Science 321, 1095-1100.
32. Sasai, Y., Kageyama, R., Tagawa, Y., Shigemoto, R. & Nakanishi, S. (1992) Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 6, 2620-2634.
33. Šestan, N., Artavanis-Tsakonas, S. & Rakic, P. (1999) Contact-dependent inhibition of cortical neurite growth mediated by Notch signaling. Science 286, 741-746.
34. 1-phase progression. Genes Dev. 13, 1501-1512.
35. Soonpaa, M.H., Koh, G.Y., Pajak, L., Jing, S., Wang, H., Franklin, M.T., Kim, K.K. & Field, L.J. (1997) Cyclin D1 overexpression promotes cardiomyocyte DNA Synthesis and multinucleation in transgenic mice. J. Clin. Invest. 99, 2644-2654.
36. Sriuranpong, V., Borges, M.W., Ravi, R.K., Arnold, D.R., Nelkin, B.D., Baylin, S.B. & Ball, D.W. (2001) Notch signaling induces cell cycle arrest in small cell lung cancer cells. Cancer Res. 61, 3200-3205.
37. Suh, J.M., Gao, X., McKay, J., McKay, R., Salo, Z. & Graff, J.M. (2006) Hedgehog signaling plays a conserved role in inhibiting fat formation. Cell Metab. 3, 25-34.
38. Takebayashi, K., Sasai, Y., Sakai, Y., Watanabe, T., Nakanishi, S. & Kageyama, R. (1994) Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. J. Biol. Chem. 269, 5150-5156.
39. Tang, Q.-Q., Otto, T.C. & Lane, M.D. (2003) Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc. Natl Acad. Sci. USA 100, 44-49.
40. Kip1 is abrogated by c-Myc. EMBO J. 15, 6595-6604.