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Volumn 48, Issue 1, 2011, Pages 80-85

Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of liquids in awake rats;Mucosite induzida pelo metotrexato retarda o esvaziamento gástrico e o trânsito gastrointestinal de líquidos em ratos acordados

Author keywords

Gastric emptying; Gastrointestinal transit; Methotrexate; Mucositis; Rats

Indexed keywords

METHOTREXATE; MYELOPEROXIDASE;

EID: 79956300904     PISSN: 00042803     EISSN: 16784219     Source Type: Journal    
DOI: 10.1590/s0004-28032011000100016     Document Type: Article
Times cited : (19)

References (24)
  • 1
    • 0019997889 scopus 로고
    • Cellular and extracellular myeloperoxidase in pyogenic inflammation
    • Bradley PP, Christensen RD, Rothstein G. Cellular and extracellular myeloperoxidase in pyogenic inflammation. Blood. 1982;60:618-22.
    • (1982) Blood , vol.60 , pp. 618-622
    • Bradley, P.P.1    Christensen, R.D.2    Rothstein, G.3
  • 3
    • 77957187284 scopus 로고
    • Effects of methotrexate on intestinal transit in rats
    • Curd CD, Manno JE, Stewart JJ. Effects of methotrexate on intestinal transit in rats. Fundam Appl Toxicol. 1985;5: 991-6.
    • (1985) Fundam Appl Toxicol , vol.5 , pp. 991-996
    • Curd, C.D.1    Manno, J.E.2    Stewart, J.J.3
  • 5
    • 2142686649 scopus 로고    scopus 로고
    • Oral and intestinal mucositis-causes and possible treatments
    • Duncan M, Grant G. Oral and intestinal mucositis-causes and possible treatments. Aliment Pharmacol Ther. 2003;18:853-74.
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 853-874
    • Duncan, M.1    Grant, G.2
  • 6
    • 0019260924 scopus 로고
    • Inhibition of dihydrofolate reductase by methotrexate: A new look at an old problem
    • Fan CC, Vitols KS, Huennekens FM. Inhibition of dihydrofolate reductase by methotrexate: a new look at an old problem. Adv Enzyme Regul. 1980;18:41-52.
    • (1980) Adv Enzyme Regul , vol.18 , pp. 41-52
    • Fan, C.C.1    Vitols, K.S.2    Huennekens, F.M.3
  • 7
    • 0025994854 scopus 로고
    • Methotrexate: Mechanism of action, pharmacokinetics, clinical indications, and toxicity
    • Grosflam J, Weinblatt ME. Methotrexate: mechanism of action, pharmacokinetics, clinical indications, and toxicity. Curr Opin Rheumatol. 1991;3:363-8.
    • (1991) Curr Opin Rheumatol , vol.3 , pp. 363-368
    • Grosflam, J.1    Weinblatt, M.E.2
  • 8
    • 0027403650 scopus 로고
    • Regulation of gastroduodenal emptying of solids by gastropyloroduodenal contractions
    • Haba T, Sarna SK. Regulation of gastroduodenal emptying of solids by gastropyloroduodenal contractions. Am J Physiol. 1993;264:g261-71.
    • (1993) Am J Physiol , vol.264
    • Haba, T.1    Sarna, S.K.2
  • 9
    • 0038521375 scopus 로고    scopus 로고
    • Nausea and emesis remain significant problems of chemotherapy despite prophylaxis with 5-hydroxytryptamine-3 antiemetics: A University of Rochester James P. Wilmot Cancer Center Community Clinical Program Study of 360 cancer patients treated in the community
    • Hickok JT, Roscoe JA, Morrow GR, King DK, Atkins JN, Fitch TR. Nausea and emesis remain significant problems of chemotherapy despite prophylaxis with 5-hydroxytryptamine-3 antiemetics: a University of Rochester James P. Wilmot Cancer Center Community Clinical Program Study of 360 cancer patients treated in the community. Cancer. 2003;97:2880-6.
    • (2003) Cancer , vol.97 , pp. 2880-2886
    • Hickok, J.T.1    Roscoe, J.A.2    Morrow, G.R.3    King, D.K.4    Atkins, J.N.5    Fitch, T.R.6
  • 11
    • 0033979825 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents
    • Kalff JC, Schraunt WH, Billiar TR, Simmons RL, Bauer AJ. Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents. Gastroenterology. 2000;118:316-27.
    • (2000) Gastroenterology , vol.118 , pp. 316-327
    • Kalff, J.C.1    Schraunt, W.H.2    Billiar, T.R.3    Simmons, R.L.4    Bauer, A.J.5
  • 12
    • 0023926925 scopus 로고
    • Control of chemotherapy-induced diarrhoea with synthetic enkephalin BW942C: A randomised trial with placebo in patients receiving cisplatin
    • Kris M, Gralla R, Clark R, Tyson L, Groshen S. Control of chemotherapy-induced diarrhoea with synthetic enkephalin BW942C: a randomised trial with placebo in patients receiving cisplatin. J Clin Oncol. 1988;6:663-8.
    • (1988) J Clin Oncol , vol.6 , pp. 663-668
    • Kris, M.1    Gralla, R.2    Clark, R.3    Tyson, L.4    Groshen, S.5
  • 13
    • 0036312147 scopus 로고    scopus 로고
    • Methotrexate in the treatment of rheumatoid arthritis. I. In vitro effects on cells of the osteoblast lineage
    • Minaur NJ, Jefferiss C, Bhalla AK, Beresford JN. Methotrexate in the treatment of rheumatoid arthritis. I. In vitro effects on cells of the osteoblast lineage. Rheumatology. 2002;41:735-740.
    • (2002) Rheumatology , vol.41 , pp. 735-740
    • Minaur, N.J.1    Jefferiss, C.2    Bhalla, A.K.3    Beresford, J.N.4
  • 14
    • 8844234253 scopus 로고    scopus 로고
    • Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats
    • Miyazono Y, Gao F, Horie T. Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats. Scand J Gastroenterol. 2004;11:1119-27.
    • (2004) Scand J Gastroenterol , vol.11 , pp. 1119-1127
    • Miyazono, Y.1    Gao, F.2    Horie, T.3
  • 15
    • 0036940618 scopus 로고    scopus 로고
    • Cancer and chemotherapy-related upper gastrointestinal symptoms: The role of abnormal gastric motor function and its evaluation in cancer patients
    • Nelson K, Walsh D, Sheehan F. Cancer and chemotherapy-related upper gastrointestinal symptoms: the role of abnormal gastric motor function and its evaluation in cancer patients. Support Care Cancer. 2002;10:455-61.
    • (2002) Support Care Cancer , vol.10 , pp. 455-461
    • Nelson, K.1    Walsh, D.2    Sheehan, F.3
  • 17
    • 77049295181 scopus 로고
    • The simultaneous measurement of absorption and transit in the gastro-intestinal tract of the rat
    • Reynell PC, Spray GH. The simultaneous measurement of absorption and transit in the gastro-intestinal tract of the rat. J Physiol 1956;131 452-62.
    • (1956) J Physiol , vol.131 , pp. 452-462
    • Reynell, P.C.1    Spray, G.H.2
  • 18
    • 0025883843 scopus 로고
    • IL-8 causes in vivo neutrophil migration by a cell-dependent mechanism
    • Ribeiro RA, Flores CA, Cunha FQ, Ferreira SH. IL-8 causes in vivo neutrophil migration by a cell-dependent mechanism. Immunology 1991;73:472-7.
    • (1991) Immunology , vol.73 , pp. 472-477
    • Ribeiro, R.A.1    Flores, C.A.2    Cunha, F.Q.3    Ferreira, S.H.4
  • 19
    • 31144471498 scopus 로고    scopus 로고
    • The role of electrogastrography and gastrointestinal hormones in chemotherapy-related dyspeptic symptoms
    • Riezzo G, Clemente C, Leo S, Russo F. The role of electrogastrography and gastrointestinal hormones in chemotherapy-related dyspeptic symptoms. J Gastroenterol. 2005;40:1107-15.
    • (2005) J Gastroenterol , vol.40 , pp. 1107-1115
    • Riezzo, G.1    Clemente, C.2    Leo, S.3    Russo, F.4
  • 20
    • 0142179300 scopus 로고    scopus 로고
    • Decreased gastric tone and delayed gastric emptying precede neutrophil infiltration and mucosal lesion formation in indomethacin-induced gastric damage in rats
    • Souza MH, Troncon LE, Cunha FQ, Oliveira RB. Decreased gastric tone and delayed gastric emptying precede neutrophil infiltration and mucosal lesion formation in indomethacin-induced gastric damage in rats. Braz J Med Biol Res. 2003;36:1383-90.
    • (2003) Braz J Med Biol Res , vol.36 , pp. 1383-1390
    • Souza, M.H.1    Troncon, L.E.2    Cunha, F.Q.3    Oliveira, R.B.4
  • 21
    • 4344607666 scopus 로고    scopus 로고
    • Inflammation as a basis for functional GI disorders
    • Spiller RC. Inflammation as a basis for functional GI disorders. Best Pract Res Clin Gastroenterol. 2004;18:641-61.
    • (2004) Best Pract Res Clin Gastroenterol , vol.18 , pp. 641-661
    • Spiller, R.C.1
  • 22
    • 0023195465 scopus 로고
    • Methotrexate bioavailability after oral and intramuscular administration in children
    • Teresi ME, Crom WR, Chui KE, Mirro J, Evans WE. Methotrexate bioavailability after oral and intramuscular administration in children. J Pediatr. 1987;110:788-92.
    • (1987) J Pediatr , vol.110 , pp. 788-792
    • Teresi, M.E.1    Crom, W.R.2    Chui, K.E.3    Mirro, J.4    Evans, W.E.5
  • 23
    • 0028267892 scopus 로고
    • Abnormal intragastric distribution of food during gastric emptying in functional dyspepsia patients
    • Troncon LE, Bennett RJ, Ahluwalia NK, Thompson DG. Abnormal intragastric distribution of food during gastric emptying in functional dyspepsia patients. Gut. 1994;35:327-32.
    • (1994) Gut , vol.35 , pp. 327-332
    • Troncon, L.E.1    Bennett, R.J.2    Ahluwalia, N.K.3    Thompson, D.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.