Delivery of the bioactive gas hydrogen sulfide during cold preservation of rat liver: Effects on hepatic function in an ex vivo model

Artificial Organs

Volumn 35, Issue 5, 2011, Pages 508-515

  Balaban, Cecilia L ^a   Rodriguez, Joaquín V ^a   Guibert, Edgardo E ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

Author keywords

Drug kinetics; Liver; Liver function tests; Organ preservation

Indexed keywords

BODY FLUIDS; COLD STORAGE; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; HYDROGEN SULFIDE; LIVER; NITRIC OXIDE; RATS; SULFUR DETERMINATION; TARGETED DRUG DELIVERY;

CONTROL GROUPS; DIALLYL DISULFIDE; FUNCTION TESTS; HYPOTHERMIC; LIVER FUNCTION TEST; LIVER FUNCTIONS; LIVER MODELING; ORGAN PRESERVATION; RAT LIVERS; REPERFUSION;

CARBON MONOXIDE;

ALLYL SULFIDE; BROMSULFOPHTHALEIN; CARBON MONOXIDE; HYDROGEN SULFIDE; LACTATE DEHYDROGENASE; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; ENZYME RELEASE; HYPOTHERMIA; LIVER; LIVER FUNCTION; LIVER GRAFT; LIVER PERFUSION; LIVER RESECTION; MALE; NONHUMAN; ORGAN PRESERVATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 79956210066     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2011.01256.x     Document Type: Article

References (17)

1. Duca WJ, da Silva RF, Arroyo PC, etal. Liver transplantation using University of Wisconsin or Celsior preserving solutions in the portal vein and Euro-Collins in the aorta. Transplant Proc 2002;42:429-34.
2. Abba R, Kombu RS, Dignam D, etal. Polyethylene glycol modified-albumin enhances the cold preservation properties of University of Wisconsin Solution in rat liver and a hepatocyte cell line. J Surg Res 2010;164:95-104.
3. 2S be the third endogenous gaseous transmitter? FASEB J 2002;16:1792-8.
4. Ebrahimkhani MR, Mani AR, Moore K. Hydrogen sulphide and the hyperdynamic circulation in cirrhosis: a hypothesis. Gut 2005;54:1668-71.
5. Saurabh J, Calvert JW, Duranski MR, Ramachandran A, Lefer DJ. Hydrogen sulphide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling. Am J Physiol Heart Circ Physiol 2008;295:801-6.
6. Benavides G, Squadrito GL, Mills RW, etal. Hydrogen sulfide mediates the vasoactivity of garlic. Proc Natl Acad Sci U S A 2007;104:17977-82.
7. Rodríguez JV, Guibert EE, Quintana AB, Scandizzi AL, Almada LL. Role of sodium nitroprusside in the improvement of rat liver preservation in University of Wisconsin solution: a study in the isolated perfused liver model. J Surg Res 1999;87:201-8.
8. Shaik I, Jancy G, Thekkumkara T, Mehvar R. Protective effects of diallyl sulfide, a garlic constituent, on the warm hepatic ischemia-reperfusion injury in a rat model. Pharm Res 2008;25:2231-42.
9. Urata K, Nguyen B, Brault A, Lavoie J, Rocheleau B, Huet PM. Decreased survival in rat liver transplantation with extended cold preservation: role of portal vein clamping time. Hepatology 1998;28:366-73.
10. Fuller BJ, Attenburrow VD, Newsome C. Experimental studies on continuous hypothermic liver perfusion with a synthetic solution containing gelatin polypeptides (haemaccel). Cryobiology 1978;15:279-89.
11. Pizarro MD, Rodriguez JV, Mamprin ME, etal. Protective effects of a carbon monoxide-releasing molecule (CORM-3) during hepatic cold preservation. Cryobiology 2005;58:248-55.
12. Carr RS, Neff JM. Quantitative semi-automated enzymatic assay for tissue glycogen. Comp Biochem Physiol 1984;77:447-9.
13. Richards TG, Tindall VR, Young AA. A modification of the bromosulphtalein liver function test to predict the dye content of the liver and bile. Clin Sci 1959;18:499-522.
14. Gnaiger E. Oxygen solubility in experimental media. Mitochondrial Physiology Network 20012004;6:1-6. Available at: Accessed August 6, 2010.
15. Quintana AB, Guibert EE, Rodríguez JV. Effect of cold preservation/reperfusion on glycogen content of liver. Concise review. Ann Hepatol 2005;4:25-31.
16. Nakao A, Sugimoto R, Billiar TR, McCurry KR. Therapeutical antioxidant medical gas. J Clin Biochem Nutr 2009;44:1-13.
17. 2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis. Hepatology 2005;42:539-48.