Inhibition of ATP-sensitive K+ channels and L-type Ca 2+ channels by amiodarone elicits contradictory effect on insulin secretion in MIN6 cells

Journal of Pharmacological Sciences

Volumn 116, Issue 1, 2011, Pages 73-80

  Nishida, Atsushi ^a   Takizawa, Taichi ^a   Matsumoto, Akio ^a   Miki, Takashi ^a   Seino, Susumu ^b   Nakaya, Haruaki ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amiodarone; Insulin; Quinidine; cell

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; AMIODARONE; CALCIUM CHANNEL L TYPE; INSULIN; NIFEDIPINE; QUINIDINE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; HYPOGLYCEMIA; IC 50; INSULIN RELEASE; MEMBRANE CURRENT; MEMBRANE DEPOLARIZATION; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATCH CLAMP; STEADY STATE; WHOLE CELL;

EID: 79956209844     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10294FP     Document Type: Article

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