Validation of pN2 sub-classifications in patients with pathological stage IIIA N2 non-small cell lung cancer

Interactive Cardiovascular and Thoracic Surgery

Volumn 12, Issue 5, 2011, Pages 733-737

  Nakagiri, Tomoyuki ^a   Sawabata, Noriyoshi ^a   Funaki, Souichirou ^a   Inoue, Masayoshi ^a   Kadota, Yoshihisa ^a   Shintani, Yasushi ^a   Okumura, Meinoshin ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Clinical n factor; Highest metastasis; Lung cancer; Lymph node metastasis sub classification; Multiple station n2; Skip n2; Stage iiia

Indexed keywords

ADULT; AGE; AGED; ARTICLE; CANCER RECURRENCE; CANCER STAGING; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; LUNG SURGERY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; SEX DIFFERENCE; SURVIVAL RATE; TUMOR LOCALIZATION; VALIDATION STUDY;

ADULT; AGED; CARCINOMA, NON-SMALL-CELL LUNG; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; JAPAN; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PNEUMONECTOMY; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME;

EID: 79956205028     PISSN: 15699293     EISSN: 15699285     Source Type: Journal    
DOI: 10.1510/icvts.2010.249896     Document Type: Article

References (15)

1. Sakao Y, Miyamoto H, Yamazaki A, Oh T, Fukai R, Shiomi K, Saito Y. Prognostic significance of metastasis to the highest mediastinal lymph node in non-small lung cancer. Ann Thorac Surg 2006;81:292-297.
2. Inoue M, Sawabata N, Takeda S, Ohta M, Ohno Y, Maeda H. Results of surgical intervention for p-stage IIIA (N2) non-small cell lung cancer: acceptable prognosis predicted by complete resection in patients with single N2 disease with primary tumor in the upper lobe. J Thorac Cardiovasc Surg 2004;127:1100-1106.
3. Saito M, Kato H. Prognostic factor in patients with pathological and N2 non-small cell lung cancer. Ann Thorac Cardiovasc Surg 2008;14:1-2.
4. Riquet M, Assouad J, Bagan P, Foucault C, Le Pimpec Barthes F, Dujon A, Danel C. Skip mediastinal lymph node metastasis and lung cancer: a particular N2 subgroup with a better prognosis. Ann Thorac Surg 2005; 79:225-233.
5. Kato H, editor. Classification of lung cancer, 1st English edition. Tokyo: The Japan Lung Cancer Society Kanehara & Co., Ltd., 2000.
6. Sobin LH, Wittekind Ch, editors. UICC: TNM classification of malignant tumors, 5th edition. New York: John Wiley & Sons, 1997.
7. Naruke T, Suemasu K, Ishikawa S. Lymph node mapping and curability at various levels of metastasis in resected lung cancer. J Thorac Cardiovasc Surg 1978;76:832-839.
8. Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer 1976;34:585-612.
9. Prenzel KL, Mönig SP, Sinning JM, Baldus SE, Brochhagen HG, Schneider PM, Hölscher AH. Lymph node size and metastatic infiltration in nonsmall cell lung cancer. Chest 2003;123:463-467.
10. Andre F, Grunenwald D, Pignon JP, Dujon A, Pujol JL, Brichon PY, Brouchet L, Quoix E, Westeel V, Chevalier TL. Survival of patients with resected N2 non-small-cell lung cancer: evidence for a subclassification and implications. J Clin Oncol 2000;18:2981-2989.
11. Robinson LA, Wagner H Jr, Ruckdeschel JC. Treatment of stage IIIA nonsmall cell lung cancer. Chest 2003;123:202S-220S.
12. Miyamoto H, Hata E, Sakao Y, Harada R, Hamada T. Evaluation of neck lymph node dissection and extended lymphadenectomy through a collar incision and median sternotomy for lung cancer. Jpn J Thorac Cardiovasc Surg 1995;16:1804-1809.
13. Riquet M, Hidden G, Debesse B. Direct lymphatic drainage of lung segments to mediastinal nodes. J Thorac Cardiovasc Surg 1989;97:625-632.
14. Casali C, Stefani A, Natali P, Rossi, G, Morandi U. Prognostic factors in surgically resected N2 non-small cell lung cancer: the importance of patterns of mediastinal lymph nodes metastasis. Eur J Cardiothorac Surg 2005;28:33-38.
15. Izbicki JR, Passlick B, Pantel K, Pichlmeier U, Hosch SB, Karg O, Thetter O. Effectiveness of radical systematic mediastinal lymphadenectomy in patients with resectable non-small cell lung cancer. Ann Surg 1998; 227:138-144.