-
1
-
-
28244438381
-
The RGK family: a regulatory tail of small GTP-binding proteins
-
Kelly K. The RGK family: a regulatory tail of small GTP-binding proteins. Trends Cell Biol. 2005, 15:640.
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 640
-
-
Kelly, K.1
-
2
-
-
0027741390
-
Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans
-
Reynet C., Kahn C.R. Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans. Science 1993, 262:1441-1444.
-
(1993)
Science
, vol.262
, pp. 1441-1444
-
-
Reynet, C.1
Kahn, C.R.2
-
3
-
-
0030595132
-
Overexpression of Rad inhibits glucose uptake in cultured muscle and fat cells
-
Moyers J.S., Bilan P.J., Reynet C., Kahn C.R. Overexpression of Rad inhibits glucose uptake in cultured muscle and fat cells. J. Biol. Chem. 1996, 271:23111-23116.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23111-23116
-
-
Moyers, J.S.1
Bilan, P.J.2
Reynet, C.3
Kahn, C.R.4
-
4
-
-
33645221822
-
Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level
-
Ilany J., Bilan P.J., Kapur S., Caldwell J.S., et al. Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level. Proc. Natl. Acad. Sci. USA 2006, 103:4481-4486.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 4481-4486
-
-
Ilany, J.1
Bilan, P.J.2
Kapur, S.3
Caldwell, J.S.4
-
5
-
-
0030910312
-
Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II
-
Moyers J.S., Bilan P.J., Zhu J., Kahn C.R. Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II. J. Biol. Chem. 1997, 272:11832-11839.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11832-11839
-
-
Moyers, J.S.1
Bilan, P.J.2
Zhu, J.3
Kahn, C.R.4
-
6
-
-
79956217799
-
Nuclear sequestration of beta-subunits by Rad and Rem is controlled by 14-3-3 and calmodulin and reveals a novel mechanism for Ca(2+) channel regulation.
-
P. Beguin, R.N. Mahalakshmi, K. Nagashima, D.H. Cher, et al., Nuclear sequestration of beta-subunits by Rad and Rem is controlled by 14-3-3 and calmodulin and reveals a novel mechanism for Ca(2+) channel regulation. J. Mol. Biol. (2005).
-
(2005)
J. Mol. Biol.
-
-
Beguin, P.1
Mahalakshmi, R.N.2
Nagashima, K.3
Cher, D.H.4
-
7
-
-
20144366024
-
Rad GTPase attenuates vascular lesion formation by inhibition of vascular smooth muscle cell migration
-
Fu M., Zhang J., Tseng Y.H., Cui T., et al. Rad GTPase attenuates vascular lesion formation by inhibition of vascular smooth muscle cell migration. Circulation 2005, 111:1071-1077.
-
(2005)
Circulation
, vol.111
, pp. 1071-1077
-
-
Fu, M.1
Zhang, J.2
Tseng, Y.H.3
Cui, T.4
-
8
-
-
0037092045
-
The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway
-
Ward Y., Yap S.F., Ravichandran V., Matsumura F., et al. The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway. J. Cell Biol. 2002, 157:291-302.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 291-302
-
-
Ward, Y.1
Yap, S.F.2
Ravichandran, V.3
Matsumura, F.4
-
9
-
-
0345060805
-
Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases
-
Finlin B.S., Crump S.M., Satin J., Andres D.A. Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases. Proc. Natl. Acad. Sci. USA 2003, 100:14469-14474.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14469-14474
-
-
Finlin, B.S.1
Crump, S.M.2
Satin, J.3
Andres, D.A.4
-
10
-
-
76349089147
-
Rad as a novel regulator of excitation-contraction coupling and {beta}-adrenergic signaling in heart
-
Wang G., Zhu X., Xie W., Han P., et al. Rad as a novel regulator of excitation-contraction coupling and {beta}-adrenergic signaling in heart. Circ. Res. 2010, 106:317-327.
-
(2010)
Circ. Res.
, vol.106
, pp. 317-327
-
-
Wang, G.1
Zhu, X.2
Xie, W.3
Han, P.4
-
11
-
-
34447650961
-
Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart
-
Yada H., Murata M., Shimoda K., Yuasa S., et al. Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart. Circ. Res. 2007, 101:69-77.
-
(2007)
Circ. Res.
, vol.101
, pp. 69-77
-
-
Yada, H.1
Murata, M.2
Shimoda, K.3
Yuasa, S.4
-
12
-
-
37349037208
-
Rad GTPase deficiency leads to cardiac hypertrophy
-
Chang L., Zhang J., Tseng Y.H., Xie C.Q., et al. Rad GTPase deficiency leads to cardiac hypertrophy. Circulation 2007, 116:2976-2983.
-
(2007)
Circulation
, vol.116
, pp. 2976-2983
-
-
Chang, L.1
Zhang, J.2
Tseng, Y.H.3
Xie, C.Q.4
-
13
-
-
79956216733
-
Rad GTPase inhibits cardiac fibrosis through connective tissue growth factor
-
Zhang J., Chang L., Chen C., Zhang M., et al. Rad GTPase inhibits cardiac fibrosis through connective tissue growth factor. Cardiovasc. Res. 2011, 10.1093/cvr/cvr068.
-
(2011)
Cardiovasc. Res.
-
-
Zhang, J.1
Chang, L.2
Chen, C.3
Zhang, M.4
-
14
-
-
33645747309
-
The Rac and Rho hall of fam: a decade of hypertrophic signaling hits
-
Brown J.H., Del Re D.P., Sussman M.A. The Rac and Rho hall of fam: a decade of hypertrophic signaling hits. Circ. Res. 2006, 98:730-742.
-
(2006)
Circ. Res.
, vol.98
, pp. 730-742
-
-
Brown, J.H.1
Del Re, D.P.2
Sussman, M.A.3
-
15
-
-
31844450444
-
Targeting Rho and Rho-kinase in the treatment of cardiovascular disease
-
Budzyn K., Marley P.D., Sobey C.G. Targeting Rho and Rho-kinase in the treatment of cardiovascular disease. Trends Pharmacol. Sci. 2006, 27:97.
-
(2006)
Trends Pharmacol. Sci.
, vol.27
, pp. 97
-
-
Budzyn, K.1
Marley, P.D.2
Sobey, C.G.3
-
16
-
-
15244358746
-
Small guanine nucleotide-binding protein Rho and myocardial function
-
Ren J., Fang C.X. Small guanine nucleotide-binding protein Rho and myocardial function. Acta Pharmacol. Sin. 2005, 26:279-285.
-
(2005)
Acta Pharmacol. Sin.
, vol.26
, pp. 279-285
-
-
Ren, J.1
Fang, C.X.2
-
17
-
-
34548170490
-
Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis
-
Shen T., Zheng M., Cao C., Chen C., et al. Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis. J. Biol. Chem. 2007, 282:23354-23361.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23354-23361
-
-
Shen, T.1
Zheng, M.2
Cao, C.3
Chen, C.4
-
18
-
-
0037278026
-
Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells
-
Zhu X., Lin Y., Zhang J., Fu M., et al. Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells. Cell. Mol. Life Sci. 2003, 60:212-218.
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 212-218
-
-
Zhu, X.1
Lin, Y.2
Zhang, J.3
Fu, M.4
-
19
-
-
11144307292
-
STRESS signaling pathways that modulate cardiac myocyte apoptosis
-
Baines C.P., Molkentin J.D. STRESS signaling pathways that modulate cardiac myocyte apoptosis. J. Mol. Cell. Cardiol. 2005, 38:47-62.
-
(2005)
J. Mol. Cell. Cardiol.
, vol.38
, pp. 47-62
-
-
Baines, C.P.1
Molkentin, J.D.2
-
20
-
-
3242804434
-
Network integration of the adrenergic system in cardiac hypertrophy
-
Barki-Harrington L., Perrino C., Rockman H.A. Network integration of the adrenergic system in cardiac hypertrophy. Cardiovasc. Res. 2004, 63:391-402.
-
(2004)
Cardiovasc. Res.
, vol.63
, pp. 391-402
-
-
Barki-Harrington, L.1
Perrino, C.2
Rockman, H.A.3
-
21
-
-
33748645920
-
Acute myocardial infarction and heart failure: role of apoptosis
-
Abbate A., Bussani R., Amin M.S., Vetrovec G.W., et al. Acute myocardial infarction and heart failure: role of apoptosis. Int. J. Biochem. Cell Biol. 2006, 38:1834-1840.
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, pp. 1834-1840
-
-
Abbate, A.1
Bussani, R.2
Amin, M.S.3
Vetrovec, G.W.4
-
22
-
-
3342948524
-
Statins inhibit {beta}-adrenergic receptor-stimulated apoptosis in adult Rat ventricular myocytes via a Rac1-dependent mechanism
-
Ito M., Adachi T., Pimentel D.R., Ido Y., et al. Statins inhibit {beta}-adrenergic receptor-stimulated apoptosis in adult Rat ventricular myocytes via a Rac1-dependent mechanism. Circulation 2004, 110:412-418.
-
(2004)
Circulation
, vol.110
, pp. 412-418
-
-
Ito, M.1
Adachi, T.2
Pimentel, D.R.3
Ido, Y.4
-
23
-
-
34247200969
-
RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis
-
Del Re D.P., Miyamoto S., Brown J.H. RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis. J. Biol. Chem. 2007, 282:8069-8078.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 8069-8078
-
-
Del Re, D.P.1
Miyamoto, S.2
Brown, J.H.3
-
24
-
-
8844235617
-
The mitochondrial death pathway and cardiac myocyte apoptosis
-
Crow M.T., Mani K., Nam Y.-J., Kitsis R.N. The mitochondrial death pathway and cardiac myocyte apoptosis. Circ. Res. 2004, 95:957-970.
-
(2004)
Circ. Res.
, vol.95
, pp. 957-970
-
-
Crow, M.T.1
Mani, K.2
Nam, Y.-J.3
Kitsis, R.N.4
-
25
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993, 74:609-619.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
26
-
-
0033528695
-
Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion
-
Ma X.L., Kumar S., Gao F., Louden C.S., et al. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation 1999, 99:1685-1691.
-
(1999)
Circulation
, vol.99
, pp. 1685-1691
-
-
Ma, X.L.1
Kumar, S.2
Gao, F.3
Louden, C.S.4
-
27
-
-
0742270609
-
P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli
-
Porras A., Zuluaga S., Black E., Valladares A., et al. P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Mol. Biol. Cell 2004, 15:922-933.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 922-933
-
-
Porras, A.1
Zuluaga, S.2
Black, E.3
Valladares, A.4
-
28
-
-
0033525760
-
An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia
-
Mackay K., Mochly-Rosen D. An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia. J. Biol. Chem. 1999, 274:6272-6279.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6272-6279
-
-
Mackay, K.1
Mochly-Rosen, D.2
-
29
-
-
0028820587
-
Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1
-
Zhang S., Han J., Sells M.A., et al. Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1. J. Biol. Chem. 1995, 270:23934-23936.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23934-23936
-
-
Zhang, S.1
Han, J.2
Sells, M.A.3
-
30
-
-
0028875683
-
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
-
Bagrodia S., Dérijard B., Davis R.J., Cerione R.A. Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 1995, 270:27995-27998.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27995-27998
-
-
Bagrodia, S.1
Dérijard, B.2
Davis, R.J.3
Cerione, R.A.4
-
31
-
-
16244406892
-
Role of p38[alpha] MAPK in cardiac apoptosis and remodeling after myocardial infarction
-
Ren J., Zhang S., Kovacs A., Wang Y., et al. Role of p38[alpha] MAPK in cardiac apoptosis and remodeling after myocardial infarction. J. Mol. Cell. Cardiol. 2005, 38:617-623.
-
(2005)
J. Mol. Cell. Cardiol.
, vol.38
, pp. 617-623
-
-
Ren, J.1
Zhang, S.2
Kovacs, A.3
Wang, Y.4
-
32
-
-
16244406892
-
Role of p38[alpha] MAPK in cardiac apoptosis and remodeling after myocardial infarction
-
Ren J., Zhang S., Kovacs A., Wang Y., et al. Role of p38[alpha] MAPK in cardiac apoptosis and remodeling after myocardial infarction. J. Mol. Cell. Cardiol. 2005, 38:617.
-
(2005)
J. Mol. Cell. Cardiol.
, vol.38
, pp. 617
-
-
Ren, J.1
Zhang, S.2
Kovacs, A.3
Wang, Y.4
|