Challenges of nanoparticle engineering for cancer therapeutics

Therapeutic Delivery

Volumn 2, Issue 5, 2011, Pages 545-548

  Berti, Lorenzo ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

biodistribution; cancer; drug delivery; nanoparticles; triggered release; tumor targeting

Indexed keywords

DOXORUBICIN; LIPOSOME; NANOCARRIER; NANOMATERIAL; NANOPARTICLE; PACLITAXEL; POLYMER;

BIOCOMPATIBILITY; CANCER THERAPY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG TARGETING; DRUG UPTAKE; MICELLE; NANOENCAPSULATION; NANOENGINEERING; PARTICLE SIZE; PRIORITY JOURNAL; REVIEW;

EID: 79956154874     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.11.36     Document Type: Review

References (20)

1. Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2, 751-760 (2007). (Pubitemid 350223348)
2. Liong M, Lu J, Kovochich M et al. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. ACS Nano 2, 889-896 (2008).
3. Ferrari M. Cancer nanotechnology: Opportunities and challenges. Nat. Rev. Cancer 5, 161-171 (2005). (Pubitemid 40314948)
4. Parveen S, Sahoo SK. Polymeric nanoparticles for cancer therapy. J. Drug Target. 16, 108-123 (2008). (Pubitemid 351266548)
5. Bhattacharyya S, Kudgus RA, Bhattacharya R, Mukherjee P. Inorganic nanoparticles in cancer therapy. Pharm. Res. 28, 237-259 (2011).
6. Danhier F, Feron O, Preat V. To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J. Control. Release 148, 135-146 (2010).
7. Holback H, Yeo Y. Intratumoral drug delivery with nanoparticulate carriers. Pharm. Res. DOI 10.1007/sI I095-010-0360-y (2011) (Epub ahead of print).
8. Greish K. Enhanced permeability and retention of macromolecular drugs in solid tumors: A royal gate for targeted anticancer nanomedicines. J. Drug Target. 15, 457-464 (2007). (Pubitemid 47209047)
9. Storm G, Belliot SO, Daemen T, Lasic DD. Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system. Adv. Drug Deliver. Rev. 17, 31-48 (1995).
10. Byrne JD, Betancourt T, Brannon-Peppas L. Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv. Drug Deliver. Rev. 60, 1615-1626 (2008).
11. Walczyk D, Bombelli FB, Monopoli MP, Lynch I, Dawson KA. What the cell 'sees' in bionanoscience. J. Am. Chem. Soc. 132, 5761-5768 (2010).
12. He C, Hu Y, Yin L, Tang C, Yin C. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials 31, 3657-3666 (2010).
13. Decuzzi P, Godin B, Tanaka T et al. Size and shape effects in the biodistribution of intravascularly injected particles. J. Control. Release 141, 320-327 (2010).
14. Yang K, Ma Y-Q. Computer simulation of the translocation of nanoparticles with different shapes across a lipid bilayer. Nat. Nanotechnol. 5, 579-583 (2010).
15. Wong C, Stylianopoulos T, Cui J et al. Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc. Natl Acad. Sci. USA 108, 2426-2431 (2011).
16. Gao W, Chan JM, Farokhzad OC. pH-responsive nanoparticles for drug delivery. Mol. Pharm. 7, 1913-1920 (2010).
17. Harris TJ, von Maltzahn G, Lord ME et al. Protease-triggered unveiling of bioactive nanoparticles. Small 4, 1307-1312 (2008).
18. Soppimath KS, Aminabhavi TM, Kulkarni AR, Rudzinski WE. Biodegradable polymeric nanoparticles as drug-delivery devices. J. Control. Release 70, 1-20 (2001). (Pubitemid 32144788)
19. Kong SD, Zhang W, Lee JH et al. Magnetically vectored nanocapsules for tumor penetration and remotely switchable on-demand drug release. Nano Lett. 10, 5088-5092 (2010).
20. Pissuwan D, Valenzuela SM, Cortie MB Therapeutic possibilities of plasmonically heated gold nanoparticles. Trends Biotechnol. 24, 62-67 (2006). (Pubitemid 43151977)