Indigofera aspalathoides protection against 20-methylcholanthrene-induced experimental fibrosarcoma growth after transplantation in rats - Role of xenobiotic drug metabolizing enzymes

Asian Pacific Journal of Cancer Prevention

Volumn 11, Issue 6, 2010, Pages 1833-1838

  Kumar, S Selva ^a   Karrunakaran, C M ^a   Rao, M Ram Krishna ^a   Balasubramanian, M P ^b  

^a BHARATH UNIVERSITY   (India)

^b UNIVERSITY OF MADRAS   (India)

Author keywords

Chemoprevention; Fibrosarcoma growth; Indigofera aspalathoides; Rat transplantation

Indexed keywords

EID: 79956149755     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Ames BN (1990). Natural carcinogens: They are found in many foods; In. Health and Environment Digest. B Murdoch, pp-4.
2. Bishop JM (1991). Molecular themes in carcinogenesis. Cell, 64, 235-48.
3. Boyd MR, Burka LT (1978). In vivo studies on the relationship between target organ alkylation and pulmonary toxicity of a chemically reactive metabolite, 4-ipomenol. J Pharmacol Exp Thera, 207, 687-97.
4. Brien PJO, Rahimtula AD (1978). Methods in Enzymology L. II, Colomick S.P. and Caplan N.O. (eds.) pp 408-9.
5. Brown HD, Chattopadhyaya SK, Pennigton SN, et al (1971). Mixed function oxidation in tumor. Br J Cancer, 25, 135-9.
6. Dogra SC, Khanduja KL, Sharma RR (1985). Hepatic drug metabolizing enzymes in lung tumor bearing rats. Biochem Pharmacol, 34, 3190-3.
7. Fearon ER, Vogelstein B (1990). A genetic model for colorectal tumerigenesis. Cell, 61, 759-67.
8. Feig DI, Reid TM, Loeb LA (1994). Reactive oxygen species in tumorigenesis. Cancer Res, 544, 1890-4.
9. Feuer G (2006). Hepatic metabolism and Carcinogenesis: its role in hepatoma and adenocarcinoma. Ann N YAcad Sci, 534, 541-51.
10. Gregus Z, Watkins JB, Thomson TN, et al (1982). Resistance of some Phase II biotrasformation pathways to hepatotoxins. J Pharacol Exp Ther, 222, 471-9.
11. Habig WH, Pabst MJ, Jakoby WB (1974). Glutathione-S-transferase: the first enzymetic step in Mercapturic acid formation. J Biol Chem, 249, 7130-9.
12. Hollman S, Touster O (1962). Alteration in tissue levels of UDP-glucose dehydrogenase, UDP-glucuronic acid pyrophosphatase and glucuronyl transferase induced by substances influencing the production of ascorbic acid. Biochem Biophys Acta, 62, 338-52.
13. IARC, International Agency for Research on Cancer (1973). Monographs on the evaluation of carcinogenic risk of chemicals to Man. Vol-3. Certain polycyclic aromatic hydrocarbons and heterocyclic compounds, Lyon.
14. Imai Y, Ito A and Sato R (1966). Evidence for biochemically different types of vesicles in the hepatic microsomal fraction. J Biochem, 60, 417-28.
15. Isselbacher KJ, Chrabas MF, Quinn RC (1962). The solubilisation and partial purification of glucuronyl transferase from a rabbit liver microsome. J Biol Chem, 237, 3033-6.
16. Kamath SA, Narayan KA (1972). Interaction of Ca2+ with endoplasmic reticulum of rat liver: a standardized procedure for the isolation of rat liver microsomes. Ann Biochem, 48, 53-61.
17. Kamdem L, Siest G, Magdalou J (1982). Differential toxicity of aflatoxin B in male and female rats: relationship with hepatic drug metabolizing enzymes. Biochem Pharmacol, 31, 3057-62.
18. Kathleen A, Harlin MD (1993). Sarcoma of soft tissue and bone. In: Weiss GR (Ed.), Clinical Oncology, Appleton and Lange- Connecticut. pp 264-6.
19. Karuzina II, Arachakov AJ (1994). The oxidative inactivation of Cytochrome P450 monooxygenase reactions. Free Rad Biol Med, 16, 73-97.
20. Kirtikar KR, Basu BD (2000). Illustrated Indian Medicinal plants III, Revised and enlarged Edition Vol, 3, 997-9.
21. Koster JF, Slee RG (1980). Lipid peroxidation of rat liver microsomes. Biochem Biophys Acta, 620, 489-99.
22. Lowry OH, Rosebrough NJ, Farr AL, et al (1951). Protein measurement with the folin phenol reagent. J Biol Chem, 193, 265-75.
23. Manoharan S, Balakrishna S, Menon VP, et al (2009). Chemopreventive efficacy of curcumin and pierine during 7, 12-dimethylbenz(a) anthracene induced hamster buccal pouch carcinogenesis. Singapore MedJ, 50, 139-46.
24. Matsubara T, Koike M, Touchi A, et al (1976). Quantitative determination of Cytochrome P450 in rat liver homogenate. Anal Biochem, 75, 596-603.
25. Mori T, Kitamura R, Imaoka VS, et al (1992). Examination for lipid peroxidation in liver microsomes of Guinea pigs as a causal factor in the decrease in the content of Cytochrome P450 due to ascorbic acid deficiency. Res Commun Chem Pathol Pharmacol, 75, 209-30.
26. Mouelhi ME, Didolkar MS, Elias EG, et al (1987). Hepatic drug metabolizing enzymes in primary and secondary tumors of human liver. Cancer Res, 47, 460-6.
27. Nadkarni KM (1982). The Indian Meteria Medica: Vol I, 677-8.
28. Nagarajan B and Sankaran S (1973). A rapid method for the production of Fibrosarcoma. Ind J Cancer, 10, 83-4.
29. Omura T, Sato R (1964). The carbon monoxide binding pigment of liver mirosomes. J Biol Chem, 239, 2370-8.
30. Philips AH, Langdon RG (1962). Hepatic triphosphopyridine nucleotide cytochrome C reductase: isolation, characterization and Kinetic Studies. J Biol Chem, 237, 2652-60.
31. Raisuddin J, Parmar D, Zaidi SIA, et al (1994). Aflatoxin induced depletion of Phase I biotransformation enzymes in growing rats. Eur J Drug Metab Pharmacokinetics, 49, 163-8.
32. Rao MS, Kakkinakis DM, Subbarao V, et al (1987). Peroxisome proliferator induced hepatocarcinogenesis: levels of activating and detoxifying enzymes in hepatocellular carcinoma induced by cirofibrate. Carcinogenesis, 8,19-23.
33. Roy D, Liehr JG (1988). Characterization of drug metabolism enzymes in estrogen- induced kidney tumor in male Syrian Hamsters. Cancer Res, 48, 5726-8.
34. Staal GEJ, Visser J and Veegar C (1969). Purification and properties of Glutathione reductase of human erythrocytes. Bichem Biophys Acta, 185, 39-48.
35. Testa B, Jenner P (1976). Drug metabolizing enzyme systems. In: Drug Metabolism: Chemical and Biochemical Aspects, Marcel Dekker, New York, pp 273-311.
36. Wattenberg LW (1995). What are the clinical attributes for cancer chemotherapy. Ann N YAcad Sci, 768, 73-81.
37. Wills ED (1969). Lipid peroxide formation in microsomes. Biochem J, 113, 333-341.