An integrated silicon sensor with microfluidic chip for monitoring potassium and pH

Microfluidics and Nanofluidics

Volumn 10, Issue 5, 2011, Pages 1119-1125

  Sharma, Sanjiv ^a   Moniz, Anna Radomska Botelho ^a   Triantis, Iasonas ^a   Michelakis, Kostis ^a   Trzebinski, Jakub ^a,b   Azarbadegan, Alireza ^c   Field, Benjamin ^a   Toumazou, Chris ^a   Eames, Ian ^c   Cass, Anthony ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b BRUNEL UNIVERSITY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

ChemFET; Computational fluid dynamics; ISFET; Microfluidic

Indexed keywords

ANALYTES; BIOLOGICAL FLUIDS; CHEMFET; CHEMICAL SPECIES; DEVICE RESPONSE; DIFFUSION COEFFICIENTS; DIFFUSIVE TRANSPORT; EXPERIMENTAL MEASUREMENTS; FIELD EFFECTS; ISFET; MEAN FLOW; MICROFLUIDIC CHIP; NUMERICAL STUDIES; PASSIVE DIFFUSIONS; RESPONSE TIME;

CHEMICAL ANALYSIS; COMPUTATIONAL FLUID DYNAMICS; DIFFUSION; FIELD EFFECT TRANSISTORS; FLUIDIC DEVICES; MICROFLUIDICS; PH EFFECTS; POSITIVE IONS; SENSORS;

MONITORING;

EID: 79956144040     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-010-0740-y     Document Type: Article

References (15)

1. PA Auroux D Iossifidis DR Reyes A Manz 2002 Micro total analysis systems. 2. Analytical standard operations and applications Anal Chem 74 12 2637 2652 10.1021/Ac020239t 10.1021/ac020239t (Pubitemid 34651166)
2. P Bergveld 1972 Development, operation, and application of the ion-sensitive field-effect transistor as a tool for electrophysiology IEEE Trans Biomed Eng 19 5 342 351 10.1109/TBME.1972.324137
3. P Bergveld 2003 Thirty years of isfetology-what happened in the past 30 years and what may happen in the next 30 years Sens Actuator B 88 1 1 20 10.1016/S0925-4005(02)00301-5 (Pubitemid 35412494)
4. M Chudy W Wróblewski A Dybko Z Brzózka 2001 Multi-ion analysis based on versatile sensor head Sens Actuators B 78 1-3 320 325 10.1016/S0925-4005(01)00833-4 (Pubitemid 32746235)
5. DC Duffy JC McDonald OJA Schueller GM Whitesides 1998 Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) Anal Chem 70 23 4974 4984 10.1021/ac980656z (Pubitemid 28553167)
6. O Hofmann 2005 Towards microalbuminuria determination on a disposable diagnostic microchip with integrated fluorescence detection based on thin-film organic light emitting diodes Lab Chip 5 8 863 868 10.1039/b504551g (Pubitemid 41117314)
7. BC Jacquot C Lee YN Shen EC Kan 2007 Time-resolved charge transport sensing by chemoreceptive neuron mos transistors (cvmos) with microfluidic channels IEEE Sens J 7 9-10 1429 1434 10.1109/JSEN.2007.904893
8. SM Kim GJ Sommer MA Burns EF Hasselbrink 2006 Low-power concentration and separation using temperature gradient focusing via joule heating Anal Chem 78 23 8028 8035 10.1021/ac061194p (Pubitemid 44871768)
9. T Masadome K Yada SI Wakida 2006 Microfluidic polymer chip integrated with an ISFET detector for cationic surfactant assay in dental rinses Anal Sci 22 8 1065 1069 10.2116/analsci.22.1065
10. MJ Milgrew MO Riehle DRS Cumming 2005 A large transistor-based sensor array chip for direct extracellular imaging Sens Actuator B 111 347 353 10.1016/j.snb.2005.01.020 (Pubitemid 41354886)
11. DR Reyes D Iossifidis PA Auroux A Manz 2002 Micro total analysis systems. 1. Introduction, theory, and technology Anal Chem 74 12 2623 2636 10.1021/Ac0202435 10.1021/ac0202435 (Pubitemid 34651165)
12. RBM Schasfoort S Schlautmann L Hendrikse A van den Berg 1999 Field-effect flow control for microfabricated fluidic networks Science 286 5441 942 945 10.1126/science.286.5441.942
13. M Schning 2002 Recent advances in biologically sensitive field-effect transistors (biofets) Analyst 127 9 1137 1151 10.1039/b204444g
14. S Sharma K Buchholz SM Luber U Rant M Tornow G Abstreiter 2006 Silicon-on-insulator microfluidic device with monolithic sensor integration for Mu-TAS applications J Microelectromech Syst 15 2 308 313 10.1109/JMEMS.2006. 872222
15. P Truman P Uhlmann M Stamm 2006 Monitoring liquid transport and chemical composition in lab on a chip systems using ion sensitive FET devices Lab Chip 6 9 1220 1228 10.1039/b604815c (Pubitemid 44290154)