Whole blood immunoassay based on centrifugal bead sedimentation

Clinical Chemistry

Volumn 57, Issue 5, 2011, Pages 753-761

  Schaff, Ulrich Y ^a   Sommer, Greg J ^a  

^a SANDIA NATIONAL LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 6; MICROSPHERE; POLYMER; REAGENT;

ARTICLE; AUTOMATION; BLOOD SAMPLING; CALIBRATION; CENTRIFUGAL ANALYZER; CENTRIFUGAL BEAD SEDIMENTATION; HUMAN; MICROFLUIDIC ANALYSIS; MOUSE; NANOFABRICATION; NONHUMAN; POINT OF CARE TESTING; SEDIMENTATION RATE; WHOLE BLOOD IMMUNOASSAY;

ANIMALS; C-REACTIVE PROTEIN; CENTRIFUGATION, ZONAL; HUMANS; IMMUNOASSAY; INTERLEUKIN-6; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSPHERES; PARTICLE SIZE;

EID: 79956130948     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2011.162206     Document Type: Article

References (27)

1. Mark D, Haeberle S, Roth G, von Stetten F, Zengerle R. Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications. Chem Soc Rev 2010;39:1153-82.
2. Yager P, Domingo GJ, Gerdes J. Point-of-care diagnostics for global health. Annu Rev Biomed Eng 2008;10:107-44.
3. Sommer GJ, Chang DS, Jain A, Langelier SM, Park J, Rhee M, et al. Introduction to microfluidics. In: Tian W-C, Finehout E, eds. Microfluidics for biological applications. New York: Springer Science (Wash DC); 2008. p 1-34.
4. Madou M, Zoval J, Jia G, Kido H, Kim J, Kim N. Lab on a CD. Annu Rev Biomed Eng 2006;8:601-28. (Pubitemid 44314828)
5. Gorkin R, Park J, Siegrist J, Amasia M, Lee BS, Park JM, et al. Centrifugal microfluidics for biomedical applications. Lab Chip 2010;10:1758-73.
6. Nagai H, Narita Y, Ohtaki M, Saito K, Wakida S. A single-bead analysis on a disk-shaped microfluidic device using an antigen-immobilized bead. Anal Sci 2007;23:975-9.
7. Honda N, Lindberg U, Andersson P, Hoffmann S, Takei H. Simultaneous multiple immunoassays in a compact disc-shaped microfluidic device based on centrifugal force. Clin Chem 2005;51:1955-61. (Pubitemid 41368195)
8. Andersson P, Jesson G, Kylberg G, Ekstrand G, Thorsen G. Parallel nanoliter microfluidic analysis system. Anal Chem 2007;79:4022-30. (Pubitemid 46903150)
9. Lai S, Wang S, Luo J, Lee LJ, Yang ST, Madou MJ. Design of a compact disk-like microfluidic platform for enzyme-linked immunosorbent assay. Anal Chem 2004;76:1832-7. (Pubitemid 38451496)
10. Riegger L, Grumann M, Nann T, Riegler J, Ehlert O, Bessler W, et al. Read-out concepts for multiplexed bead-based fluorescence immunoassays on centrifugal microfluidic platforms. Sensor Actuat a-Phys 2006;126:455-62. (Pubitemid 43165658)
11. Lee BS, Lee JN, Park JM, Lee JG, Kim S, Cho YK, Ko C. A fully automated immunoassay from whole blood on a disc. Lab Chip 2009;9:1548-55.
12. Peytavi R, Raymond FR, Gagne D, Picard FJ, Jia G, Zoval J, et al. Microfluidic device for rapid (<15 min) automated microarray hybridization. Clin Chem 2005;51:1836-44. (Pubitemid 41368174)
13. Lutz S, Weber P, Focke M, Faltin B, Hoffmann J, Muller C, et al. Microfluidic lab-on-a-foil for nucleic acid analysis based on isothermal recombinase polymerase amplification (RPA). Lab Chip 2010;10:887-93.
14. Cho YK, Lee JG, Park JM, Lee BS, Lee Y, Ko C. One-step pathogen specific DNA extraction from whole blood on a centrifugal microfluidic device. Lab Chip 2007;7:565-73. (Pubitemid 46699204)
15. Kido H, Micic M, Smith D, Zoval J, Norton J, Madou M. A novel, compact disk-like centrifugal microfluidics system for cell lysis and sample homogenization. Colloids Surf B Biointerfaces 2007;58:44-51.
16. Siegrist J, Amasia M, Singh N, Banerjee D, Madou M. Numerical modeling and experimental validation of uniform microchamber filling in centrifugal microfluidics. Lab Chip 2010;10:876-86.
17. Siegrist J, Gorkin R, Bastien M, Stewart G, Peytavi R, Kido H, et al. Validation of a centrifugal microfluidic sample lysis and homogenization platform for nucleic acid extraction with clinical samples. Lab Chip 2010;10:363-71.
18. Golorikian H, Zalesk T, Clancy B. Overview of microfluidic applications in IVDs. DX Directions 2010;1:12-6.
19. Luk VN, Mo G, Wheeler AR. Pluronic additives: a solution to sticky problems in digital microfluidics. Langmuir 2008;24:6382-9.
20. Grumann M, Geipel A, Riegger L, Zengerle R, Ducree J. Batch-mode mixing on centrifugal microfluidic platforms. Lab Chip 2005;5:560-5. (Pubitemid 40676825)
21. Park JM, Cho YK, Lee BS, Lee JG, Ko C. Multifunctional microvalves control by optical illumination on nanoheaters and its application in centrifugal microfluidic devices. Lab Chip 2007;7: 557-64. (Pubitemid 46699203)
22. Liu RH, Yang J, Lenigk R, Bonanno J, Grodzinski P. Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection. Anal Chem 2004;76:1824-31. (Pubitemid 38451495)
23. Baud M, ed. Data analysis, mathematical modeling. New York, NY: VCH Publishers; 1993. p 656-71.
24. Lim CT, Zhang Y. Bead-based microfluidic immunoassays: the next generation. Biosens Bioelectron 2007;22:1197-204. (Pubitemid 46157004)
25. Reed GF, Lynn F, Meade BD. Use of coefficient of variation in assessing variability of quantitative assays. Clin Diagn Lab Immunol 2002;9:1235-9. (Pubitemid 35283285)
26. Abi-Samra K, Hanson R, Madou M, Gorkin RA 3rd. Infrared controlled waxes for liquid handling and storage on a CD-microfluidic platform. Lab Chip 2011;11:723-6.
27. Junker R, Schlebusch H, Luppa PB. Point-of-care testing in hospitals and primary care. Dtsch Arztebl Int 2010;107:561-7.