AN RNA aptamer containing two binding sites against the HCV Minus-IRES domain I

Nucleosides, Nucleotides and Nucleic Acids

Volumn 30, Issue 3, 2011, Pages 185-202

  Konno, Keisuke ^a   Iizuka, Mana ^a   Fujita, Syusuke ^a   Nishikawa, Satoshi ^b   Hasegawa, Tsunemi ^a   Fukuda, Kotaro ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

HCV; in vitro selection; minus IRES; NS5B; RNA aptamer

Indexed keywords

APTAMER; APTAMER 30; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; HEPATITIS C VIRUS; MUTATIONAL ANALYSIS; PROTEIN DOMAIN; RNA ISOLATION; RNA SYNTHESIS; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; VIRUS REPLICATION;

APTAMERS, NUCLEOTIDE; BINDING SITES; NUCLEIC ACID CONFORMATION; RNA REPLICASE; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 79956130458     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770.2011.562475     Document Type: Article

References (25)

1. Chu, C.K.; Baker, D.C., Eds. Nucleosides, Nucleotides as Antiviral and Antitumor Agents. Plenum, New York, 1993;.
2. De Clercq, E. Antiviral drugs in current clinical use. J. Clin. Virol. 2004, 30, 115-133. (Pubitemid 38582018)
3. Liu-Young, G.; Kozal, M.J. Hepatitis C protease and polymerase inhibitors in development. AIDS Patient Care STDS 2008, 22, 449-457.
4. Vorbrüggen, H.; Ruh-Pohlenz, C. Synthesis of nucleosides. Org. React. 2000, 55, 1-630.
5. Vorbrüggen, H.; Bennua, B. Nucleoside syntheses. XXV. A new simplified nucleoside synthesis. Chem. Ber. 1981, 114, 1279-1286.
6. Bookser, B.C.; Raffaele, N.B. High-throughput five minute microwave accelerated glycosylation approach to the synthesis of nucleoside libraries. J. Org. Chem. 2007, 72, 173-179. (Pubitemid 46068217)
7. Andrzejewska, M.; Kaminski, J.; Kazimierzuk, Z. Microwave induced synthesis of ribonucleosides on solid support. Nucleosides Nucleotides Nucleic Acids 2002, 1, 73-78. (Pubitemid 34327065)
8. Nikolaus, N.V.; Bozilovic, J.; Engels, J.W. Microwave-assisted ribosylation of modified heterocyclic bases by Vorbruggen method. Nucleosides Nucleotides Nucleic Acids 2007, 26, 889-892. (Pubitemid 350223310)
9. 3 catalysts under microwave irradiation. Appl. Catal. A, 2008, 338, 9-13.
10. Vorbrüggen, H. Some recent trends and progress in nucleoside synthesis. Acta Biochem. Pol. 1996, 43, 25-36. (Pubitemid 126417408)
11. Im, J.; Kim, J.; Kim, S.; Hahn, B.; Toda, F. N-Glycosylation reactions in the solid to solid state. Tetrahedron Lett. 1997, 38, 451-452, and references therein. (Pubitemid 27034089)
12. Sebti, S.; Zahouily, M.; Lazrek, H.B.; Mayoral, J.A.; Macquerrie, D.J. Phosphates: new generation of liquid-phase heterogeneous catalysts in organic chemistry. Curr. Org. Chem. 2008, 12, 203-232.
13. Zahouily, M.; Mezdar, A.; Elmakssoudi, A.; Mounir, B.; Rayadh, A.; Sebti, S.; Lazrek, H.B. Comparison of different Lewis acids supported on natural phosphate as new catalysts for chemoselective dithioacetalization of carbonyl compounds under solvent-free conditions. ARKIVOC 2006, 31-40. (Pubitemid 41687950)
14. 7: Synthesis of alpha-amino phosphonates under solvent-free conditions at room temperature. Lett. Org. Chem. 2005, 2, 136-138.
15. Zahouily, M.; Mezdar, A.; Rakik, J.; Elmakssoudi, A.; Rayadh, A.; Sebti, S. A mild and efficient method for the protection of carbonyl compounds as dithioacetals, dithiolanes and dithianes catalysed by iodine supported on natural phosphate. J. Mol. Catal. A 2005, 233, 43-47.
16. -1
17. Baddi, L.; Smietana, M.; Vasseur, J.J.; Lazrek, H.B. A procedure for facile synthesis of nucleosides using N, O-bistrimethylsilylacetamide in the presence of natural phosphate coated with potassium iodide. Lett. Org. Chem. 2010, 7, 196-199.
18. Lazrek, H.B.; Baddi, L.; Ouzebla, D.; Smietana, M.; Vasseur, J.J. A one step synthetic approach to L-pyrimidine nucleosides using natural phosphate coated with potassium iodide as catalyst. Nucleic Acids Symposium Series 2008, 52, 549-550.
19. Lazrek, H.B.; Ouzebla, D.; Vasseur, J.J. Glycosylation reaction via a mild and efficient one-pot reaction using doped natural phosphate with iodine as catalyst. Nucleosides Nucleotides Nucleic Acids 2007, 26, 1095-1098. (Pubitemid 350223260)
20. Lazrek, H.B.; Rochdi, A.; Redwane, N.; Ouzebla, D.; Vasseur, J.J. A one pot synthesis of D-ribonucleosides using Natural phosphate doped with KI in HMDS. Lett. Org. Chem. 2006, 3, 313-314. (Pubitemid 44083081)
21. 3SiH. Tetrahedron Lett. 2003, 44, 7863-7866. (Pubitemid 37186934)
22. VanWell, R.M.; Ravindranathan, K.P.; Field, R.A. Iodine promoted glycosylation with glycosyl iodides: α-glycoside synthesis. J. Carbohydr. Chem. 2005, 24, 463-474. (Pubitemid 41653661)
23. Kulikowski, T.; Zawadzki, Z.; De Clerq, E.; Shugar, D. 5-substituted arabinofuranosyl uracil nucleosides: Synthesis and antiviral properties. Acta Biochem. Pol. 1984, 31, 341-356. (Pubitemid 15105244)
24. Fang Wu, A.; Chargaff, E. L-Uridine: Synthesis and behavior as enzyme substrate. PNAS 1969, 63, 1222-1226.
25. Génu-Dellac, C.; Gosselin, G.; Puech, F.; Henry, J.-C.; Aubertin, A.-M.; Obert, G.; Kirn, A.; Imbach, J.-L. Systematic synthesis and antiviral evaluation of α-L-arabinofuranosyl and 2'-Deoxy-α-L-erythropento- furanosyl nucleosides of the five naturally occurring nucleic acid bases. Nucleosides Nucleotides Nucleic Acids 1991, 10, 1345-1376.