Isolation and characterization of process-related impurities and degradation products in larotaxel

Journal of Pharmaceutical and Biomedical Analysis

Volumn 55, Issue 5, 2011, Pages 1190-1196

  Che, Xin ^a,b   Shen, Li ^c   Xu, Hui ^b   Liu, Ke ^a,b  

^a LIAONING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b YANTAI UNIVERSITY   (China)

^c OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Characterization; Forced degradation; Isolation; Larotaxel; Process related impurities; Stability

Indexed keywords

10 DEACETYL 7, 8 CYCLOPROPYL BACCATIN 3; 10 DEACETYL LAROTAXEL; 2',13 BISSIDECHAIN LAROTAXEL; 7 ACETYL 8 METHYL LAROTAXEL; 7,8 CYCLOPROPYL BACCATIN 3; ACID; BACCATIN III; LAROTAXEL; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG IMPURITY; DRUG ISOLATION; DRUG STRUCTURE; LIGHT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; THERMAL ANALYSIS;

ALKALOIDS; CARBON ISOTOPES; CHEMISTRY TECHNIQUES, ANALYTICAL; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, LIQUID; DRUG CONTAMINATION; DRUG STABILITY; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, CHEMICAL; REPRODUCIBILITY OF RESULTS; TAXOIDS;

EID: 79956121478     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.03.036     Document Type: Article

References (5)

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