Isolation and structure characterization of related impurities in etimicin sulfate by LC/ESI-MSn and NMR

Journal of Pharmaceutical and Biomedical Analysis

Volumn 55, Issue 5, 2011, Pages 902-907

  Wang, Hao ^a   Zhang, Zhijie ^a   Xiong, Fei ^b   Wu, Lingyun ^c   Li, Ping ^a   Ye, Wencai ^a,d  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Southeast University   (China)

^c Wuxi Jiminkexin Shanhe Pharmaceutical Co Ltd   (China)

^d JINAN UNIVERSITY   (China)

Author keywords

Aminoglycoside; Etimicin sulfate; LC ESI MSn; NMR; Related impurities

Indexed keywords

1 N ETHYL 3' N DEMETHYL GENTAMICIN C2B; 1 N ETHYL GARAMINE; 1 N ETHYL GENTAMICIN C2B; 1,3 N N DIETHYL GARAMINE; 1,3 N, N DIETHYL GENTAMICIN C1A; 2'' N ETHYL ETIMICIN; 2'' N ETHYL GENTAMICIN C1A; 3 N ETHYL GENTAMICIN C1A; 6'' DEAMINO 6'' HYDROXYL ETIMICIN; 6'' N ETHYL ETIMICIN; 6'' N ETHYL GENTAMICIN C1A; ETIMICIN; GENTAMICIN; GENTAMICIN C1A; SILICA GEL; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG IMPURITY; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; LIGHT SCATTERING; LIQUID CHROMATOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

CHEMISTRY TECHNIQUES, ANALYTICAL; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, LIQUID; GENTAMICINS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 79956117105     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.03.005     Document Type: Article

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