Allogeneic hematopoietic stem cell transplantation in glanzmann thrombasthenia complicated by platelet alloimmunization

Klinische Padiatrie

Volumn 223, Issue 3, 2011, Pages 173-175

  Wiegering, V ^a   Winkler, B ^a   Langhammer, F ^a   Wolfl M ^a   Wirbelauer, J ^a   Sauer, K ^b   Kobsar, A ^b   Meyer, T ^b   Strauss A ^b   Bakchoul, T ^c   Eyrich, M ^a   Schlegel, P G ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Glanzmann thrombasthenia; hematopoietic stem cell transplantation; platelet alloimmunization; platelet function; refractory to transfusion

Indexed keywords

ALLOANTIBODY; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; HLA ANTIGEN; IMMUNOGLOBULIN; METHOTREXATE; STEROID; THROMBOCYTE ANTIBODY; TRANEXAMIC ACID;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ALLOIMMUNIZATION; ARTICLE; BLEEDING; BLEEDING TIME; BLOOD ANALYSIS; BLOOD CLOTTING; CASE REPORT; CHILD; DISEASE COURSE; DISEASE SEVERITY; DRUG MEGADOSE; ENGRAFTMENT; EPISTAXIS; ERYTHROCYTE CONCENTRATE; FLUORESCENCE ACTIVATED CELL SORTING; GLANZMANN DISEASE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HEART FAILURE; HLA MATCHING; HUMAN; LOW DRUG DOSE; MALE; PLASMAPHERESIS; PRESCHOOL CHILD; RESPIRATORY FAILURE; SIBLING; THROMBOCYTE ANOMALY; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TREATMENT OUTCOME;

EID: 79956114852     PISSN: 03008630     EISSN: 14393824     Source Type: Journal    
DOI: 10.1055/s-0031-1273726     Document Type: Article

References (11)

1. Bellucci S, Caen J. Molecular basis of Glanzmann's Thrombasthenia and current strategies in treatment. Blood Rev 2002 16 193-202 (Pubitemid 34982976)
2. Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med 2002 346 995-1008
3. Connor P, Khair K, Liesner R. et al Stem cell transplantation for children with Glanzmann thrombasthenia. Br J Haematol 2008 140 568-571 (Pubitemid 351230067)
4. Flood VH, Johnson FL, Boshkov LK. et al Sustained engraftment post bone marrow transplant despite anti-platelet antibodies in Glanzmann thrombasthenia. Pediatr Blood Cancer 2005 45 971-975 (Pubitemid 41552168)
5. Imbach P. When a child with immune thrombocytopenia experiences life-threatening bleeding. Klin Padiatr 2010 222 337-339
6. Ishaqi MK, El-Hayek M, Gassas A. et al Allogeneic stem cell transplantation for Glanzmann thrombasthenia. Pediatr Blood Cancer 2009 52 682-683
7. Kiefel V. The MAIPA assay and its applications in immunohaematology. Transfus Med 1992 2 181-188
8. Landgraf M, Siekmeyer M, Fischer L. et al Coincidence of immune thrombocytopenia, intracranial hemorrhage and graft-versus-host disease in an 11-year-old girl. Klin Padiatr 2010 222 378-382
9. Poon MC, DOiron R, Von Depka M. et al Prophylactic and therapeutic recombinant factor VIIa administration to patients with Glanzmann's thrombasthenia: results of an international survey. J Thromb Haemost 2004 2 1096-1103
10. Schlegel N, Bardet V, Kenet G. et al Diagnostic and therapeutic considerations on inherited platelet disorders in neonates and children. Klin Padiatr 2010 222 209-214
11. Tarantino MD, Goldsmith G. Treatment of acute immune thrombocytopenic purpura. Semin Hematol 1998 35 28-35 (Pubitemid 28136665)