Significance of nuclear p-Akt in endometrial carcinogenesis: Rapid translocation of p-Akt into the nucleus by estrogen, possibly resulting in inhibition of apoptosis

International Journal of Gynecological Cancer

Volumn 21, Issue 2, 2011, Pages 194-202

  Abe, Naoya ^a,d   Watanabe, Jun ^a,b   Tsunoda, Shinpei ^b   Kuramoto, Hiroyuki ^c   Okayasu, Isao ^a,b  

^a Graduate School of Medical Sciences   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Kanagawa Health Service Association   (Japan)

^d JAPANESE RED CROSS MEDICAL CENTER   (Japan)

Author keywords

Akt; Apoptosis; Cell signaling pathway; Endometrial cancer; Estrogen

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR ALPHA; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CONTROLLED STUDY; CYTOPLASM; ENDOMETRIUM CANCER; ENDOMETRIUM HYPERPLASIA; GENE TRANSLOCATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; ISCHIKAWA CELL; LABELING INDEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

APOPTOSIS; CARCINOMA, ENDOMETRIOID; CELL NUCLEUS; CELLS, CULTURED; ENDOMETRIAL NEOPLASMS; ESTROGENS; FEMALE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 79956110832     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1097/IGC.0b013e318207964c     Document Type: Article

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