Age and gender-dependent bone density changes of the human skull disclosed by high-resolution flat-panel computed tomography

International Journal of Legal Medicine

Volumn 125, Issue 3, 2011, Pages 417-425

  Schulte Geers, Christina ^a   Obert, Martin ^a,c   Schilling, René L ^b   Harth, Sebastian ^c   Traupe, Horst ^a   Gizewski, Elke R ^a   Verhoff, Marcel A ^c  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

Age at death determination; Bone density; Flat panel volumetric computed tomography; Hounsfield unit density distribution; Sex differences

Indexed keywords

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; BONE DENSITY; CHILD; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; FORENSIC SCIENCE; HUMAN; IMAGE ENHANCEMENT; INFANT; MALE; METHODOLOGY; MIDDLE AGED; PRESCHOOL CHILD; RADIOGRAPHY; SEXUAL DEVELOPMENT; SKULL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; BONE DENSITY; CHILD; CHILD, PRESCHOOL; FEMALE; FORENSIC SCIENCES; HUMANS; IMAGE ENHANCEMENT; INFANT; MALE; MIDDLE AGED; SEX CHARACTERISTICS; SKULL; TOMOGRAPHY, X-RAY COMPUTED; YOUNG ADULT;

EID: 79956106808     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-010-0544-3     Document Type: Article

References (52)

1. E Cunha E Baccino L Martrille F Ramsthaler J Prieto Y Schuliar N Lynnerup C Cattaneo 2009 The problem of aging human remains and living individuals: a review Forensic Sci Int 193 1 13 19879075 10.1016/j.forsciint.2009.09.008 1:STN:280:DC%2BD1MjnsVWhtw%3D%3D
2. M Kellinghaus R Schulz V Vieth S Schmidt H Pfeiffer A Schmeling 2010 Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans Int J Leg Med 124 321 325 10.1007/s00414-010-0448-2
3. S Schmidt I Nitz R Schulz A Schmeling 2008 Applicability of the skeletal age determination method of Tanner and Whitehouse for forensic age diagnostics Int J Leg Med 122 309 314 10.1007/s00414-008-0237-3
4. M Kellinghaus R Schulz V Vieth S Schmidt A Schmeling 2010 Forensic age estimation in living subjects based on the ossification status of the medial clavicular epiphysis as revealed by thin-slice multidetector computed tomography Int J Leg Med 124 149 154 10.1007/s00414-009-0398-8
5. B Knell P Ruhstaller F Prieels A Schmeling 2009 Dental age diagnostics by means of radiographical evaluation of the growth stages of lower wisdom teeth Int J Leg Med 123 465 469 10.1007/s00414-009-0330-2 1:STN:280: DC%2BD1Mjgslyktg%3D%3D
6. A Olze T Solheim R Schulz M Kupfer H Pfeiffer A Schmeling 2010 Assessment of the radiographic visibility of the periodontal ligament in the lower third molars for the purpose of forensic age estimation in living individuals Int J Leg Med 124 445 448 10.1007/s00414-010-0488-7
7. A Olze T Solheim R Schulz M Kupfer A Schmeling 2010 Evaluation of the radiographic visibility of the root pulp in the lower third molars for the purpose of forensic age estimation in living individuals Int J Leg Med 124 183 186 10.1007/s00414-009-0415-y
8. R Macchiarelli L Bonduoli 1994 Linear densitometry and digital image processing of proximal femur radiographs: implications for archaeological and forensic anthropology Am J Phys Anthropol 93 109 122 8141239 10.1002/ajpa.1330930108 1:STN:280:DyaK2c7ovFKltA%3D%3D (Pubitemid 24020102)
9. C Rissech M Schaefer A Malgosa 2008 Development of the femur-implications for age and sex determination Forensic Sci Int 180 1 9 18692331 10.1016/j.forsciint.2008.06.006
10. L Ríos K Weisensee C Rissech 2008 Sacral fusion as an aid in age estimation Forensic Sci Int 180 111.e1 111.e7 10.1016/j.forsciint.2008.06.010
11. E Pasquier L De Saint Martin Pernot V Burdin C Mounayer C Le Rest D Colin D Mottier C Roux E Baccino 1999 Determination of age at death: assessment of an algorithm of age prediction using numerical three-dimensional CT data from pubic bones Am J Phys Anthropol 108 261 268 10096678 10.1002/(SICI)1096- 8644(199903)108:3<261::AID-AJPA2>3.0.CO;2-B 1:STN:280:DyaK1M7psVensA%3D%3D (Pubitemid 29124542)
12. S Brooks JM Suchey 1990 Skeletal age determination based on the os pubis: a comparison of the Acsàdi-Nemeskéri and Suchey-Brooks methods Hum Evol 5 227 238 10.1007/BF02437238 (Pubitemid 20327240)
13. O Ferrant C Rougé-Maillart L Guittet F Papin B Clin G Fau N Telmon 2009 Age at death estimation of adult males using coxal bone and CT scan: a preliminary study Forensic Sci Int 186 14 21 19201560 10.1016/j.forsciint.2008. 12.024
14. A Meinl CD Huber S Tangl GM Gruber M Teschler-Nicola G Watzek 2008 Comparison of the validity of three dental methods for the estimation of age at death Forensic Sci Int 178 96 105 18400432 10.1016/j.forsciint.2008.02.008 1:STN:280:DC%2BD1czkvV2itA%3D%3D
15. RC Dobberstein S-M Tung S Ritz-Timme 2010 Aspartic acid racemisation in purified elastin from arteries as basis for age estimation Int J Leg Med 124 269 275 10.1007/s00414-009-0392-1 1:STN:280:DC%2BC3crhtFKhuw%3D%3D
16. A Dorandeu B Coulibaly MD Piercecchi-Marti C Bartoli J Gaudart E Baccino G Leonetti 2008 Age-at-death estimation based on the study of frontosphenoidal sutures Forensic Sci Int 177 47 51 18191929 10.1016/j.forsciint.2007.10.012
17. M Obert B Ahlemeyer E Baumgart-Vogt H Traupe 2005 Flat-panel volumetric computed tomography a new method for visualizing fine bone detail in living mice J Comput Assist Tomogr 29 560 565 16012319 10.1097/01.rct.0000164254.66730.55 (Pubitemid 41060295)
18. MA Verhoff B Karger F Ramsthaler M Obert 2008 Investigations on an isolated skull with gunshot wounds using flat-panel CT Int J Leg Med 122 441 445 10.1007/s00414-008-0246-2
19. Reu C, Obert M, Schilling R, Harth S, Traupe H, Verhoff MA (2008) Automatische Analyse von hochauflösenden flat-panel Computertomographie- Bildern zur Bestimmung des Verknöcherungszustandes von Suturen zur Altersbestimmung beim Menschen. 87th Annual conference of the German forensic society, Dresden
20. M Obert C Schulte-Geers RL Schilling S Harth M Kläver H Traupe MA Verhoff 2010 High-resolution flat-panel volumetric CT images show no correlation between human age and suture obliteration-independent of sex Forensic Sci Int 180 180.e1 180.e12 10.1016/j.forsciint.2010.04.006
21. IDL reference guide, version 6.0 (2003) Research Systems Inc., RSI, Boulder, CO, USA
22. Crow EL, Davis FA, Maxfield MW (1960) Statistics manual. Dover Publications, New York
23. Zwillinger D, Kokoska S (2000) CRC standard probability and statistics tables and formulae. Chapman & Hall/CRC, Boca Raton
24. Beichelt FE, Montgomery DC (2003) Teubner-Taschenbuch der Stochastik. Wahrscheinlichkeitstheorie, Stochastische Prozesse, Mathematische Statistik. B.G. Teubner, Stuttgart
25. LA Madeline AD Elster 1995 Suture closure in the human chondrocranium: CT assessment Radiology 196 747 756 7644639 1:STN:280:DyaK2Mznt1GhtQ%3D%3D
26. MS Robinson MA Bidmos 2009 The skull and humerus in the determination of sex: reliability of discriminant function equations Forensic Sci Int 186 86.e1 86.e5 10.1016/j.forsciint.2009.01.003
27. M Steyn MY Iscan 1998 Sexual dimorphism in the crania and mandibles of South African whites Forensic Sci Int 98 9 16 10036755 10.1016/S0379-0738(98) 00120-0 1:STN:280:DyaK1M7lsFOrsg%3D%3D (Pubitemid 29069094)
28. P Steiger SR Cummings DM Black NE Spencer HK Genant 1992 Age-related decrements in bone mineral density in women over 65 J Bone Miner Res 7 625 632 1414480 10.1002/jbmr.5650070606 1:STN:280:DyaK3s%2FjsVChtg%3D%3D
29. C Ribot F Tremlliers JM Poullies JP Louvet R Guiraud 1988 Influence of the menopause and aging on spinal density in French women Bone Miner 5 89 97 3214683 10.1016/0169-6009(88)90009-8 1:STN:280:DyaL1M7gsFKrsA%3D%3D
30. S Ortolani C Trevisan ML Bianchi MP Caraceni FM Ulivieri G Gandolini A Montessano EE Polli 1991 Spinal and forearm bone mass in relation to ageing and menopause in healthy Italian women Eur J Clin Investig 21 33 39 10.1111/j.1365-2362.1991.tb01355.x 1:STN:280:DyaK3MzitleltQ%3D%3D
31. G Guglielmi GM Giannatempo BA Blunt S Grampp CC Glüer M Cammisa HK Genant 1995 Spinal bone mineral density by quantitative CT in a normal Italian population Eur Radiol 5 269 275
32. JS Jahng KS Kang HW Park MH Han 1991 Assessment of bone mineral density in postmenopausal and senile osteoporosis using quantitative CT Orthopedics 14 1101 1105 1946046 1:STN:280:DyaK38%2FltFKisQ%3D%3D
33. CE Cann HK Genant 1980 Precise measurement of vertebral mineral content using computed tomography J Comput Assist Tomogr 4 493 500 7391292 10.1097/00004728-198008000-00018 1:STN:280:DyaL3c3ivVejsQ%3D%3D (Pubitemid 10090082)
34. CD Jones AM Laval-Jeantet MH Laval-Jeantet HK Genant 1987 Importance of measurement of spongious vertebral bone mineral density in the assessment of osteoporosis Bone 8 201 206 3446255 10.1016/8756-3282(87)90165-7 1:STN:280:DyaL1c7otlyisw%3D%3D
35. M Nilsson O Johnell K Johnsson I Redlund-Johnell 1988 Quantitative computed tomography in measurement of vertebral trabecular bone mass Acta Radiol 29 719 725 3190950 1:STN:280:DyaL1M%2FltVKrsA%3D%3D (Pubitemid 19004722)
36. PJ Kelly T Nguyen J Hopper N Pocock P Sambrook J Eisman 1993 Changes in axial bone density with age: a twin study J Bone Miner Res 8 11 17 8427043 10.1002/jbmr.5650080103 1:STN:280:DyaK3s7ltV2msg%3D%3D (Pubitemid 23033991)
37. SR Cummings DM Black MC Nevitt W Browner J Cauley K Ensrud HK Genant L Palermo J Scott TM Vogt 1993 Bone density at various sites for prediction of hip fractures Lancet 341 72 75 8093403 10.1016/0140-6736(93)92555-8 1:STN:280:DyaK3s7hs1GisA%3D%3D (Pubitemid 23028113)
38. AE Burgess B Colborne E Zoffmann 1987 Vertebral trabecular bone: comparison of single and dual-energy CT measurements with chemical analysis J Comput Assist Tomogr 11 506 515 3571596 10.1097/00004728-198705000-00026 1:STN:280:DyaL2s7psFKgsA%3D%3D (Pubitemid 17081524)
39. CE Cann 1987 QCT applications: comparison of current scanners Radiology 162 257 261 3786773 1:STN:280:DyaL2s%2FmvVCgtQ%3D%3D (Pubitemid 17001820)
40. CE Cann 1988 Quantitative CT for determination of bone mineral density: a review Radiology 166 509 522 3275985 1:STN:280:DyaL1c%2FpvVWrsQ%3D%3D (Pubitemid 18030768)
41. JH Tobias D Cook TJ Chambers N Dalzell 1993 Low spinal bone mass in Asian women reflects their small skeletal size J Bone Miner Res 8 S330
42. DP De Simone J Stevens J Edwards J Shary L Gordon NH Bell 1989 Influence of body habitus and race on bone mineral density of the midradius, hip and spine in aging women J Bone Miner Res 4 827 830 (Pubitemid 20065691)
43. MM Luckey DE Meier JP Mandeli MC Da Costa MC Hubbard SJ Goldsmith 1989 Radial and vertebral bone density in white and black women: evidence for racial differences in premenopausal bone homeostasis J Clin Endocrinol Metab 69 762 770 2778034 10.1210/jcem-69-4-762 1:STN:280:DyaL1MzotVOgtQ%3D%3D (Pubitemid 19245854)
44. J Harbison L Daly B Murphy C Mc Coy J Masterson 1992 Normal bone density in Irish women: is American normative data suitable for use in Ireland? Ir J Med Sci 16 66 69 10.1007/BF02983715
45. EA Krall B Dawson-Hughes 1993 Heritable and life-style determinants of bone mineral density J Bone Miner Res 8 1 9 8427042 10.1002/jbmr.5650080102 1:STN:280:DyaK3s7ltV2nug%3D%3D (Pubitemid 23033990)
46. IR Reid M Mackie HK Ibbertson 1986 Bone mineral content in Polynesian and white New Zealand women Brit Med J 292 1547 1548 10.1136/bmj.292.6535.1547 1:STN:280:DyaL283ksVSkuw%3D%3D (Pubitemid 16080831)
47. Y Liel J Edwards J Shary 1988 Effect of race and body habitus on bone mineral density of the radius, hip, and spine in premenopausal women J Clin Endocrinol Metab 66 1247 1250 3372686 10.1210/jcem-66-6-1247 1:STN:280:DyaL1c3ivVCjug%3D%3D
48. RB Mazess HS Barden 1991 Bone density in premenopausal women: effect of age, dietary intake, physical activity, smoking, and birth-control pills Am J Clin Nutr 53 132 142 1984338 1:STN:280:DyaK3M%2Fns1Wlsg%3D%3D (Pubitemid 21917621)
49. JS Johnson 1976 A comparison of age estimation using discriminant function analysis with some other estimations of unknown skulls J Anat 121 475 484 190196 1:STN:280:DyaE2s7hvVartQ%3D%3D
50. CO Lovejoy RS Meindl RP Mensforth TJ Barton 1985 Multifactorial determination of skeletal age at death: a method and blind tests of its accuracy Am J Phys Anthropol 68 1 14 4061595 10.1002/ajpa.1330680102 1:STN:280:DyaL28%2FkvVWjsQ%3D%3D (Pubitemid 15021695)
51. I Hershkovitz B Latimer O Dutour LM Jellema S Wish-Baratz C Rothschild BM Rothschild 1997 Why do we fail in aging the skull from the sagittal suture? Am J Phys Anthropol 103 393 399 9261501 10.1002/(SICI)1096-8644(199707)103: 3<393::AID-AJPA8>3.0.CO;2-R 1:STN:280:DyaK2svgsVOqsQ%3D%3D (Pubitemid 27327593)
52. D Sahni I Jit S Neelam 2005 Time of closure of cranial sutures in northwest Indian adults Forensic Sci Int 148 199 205 15739299 10.1016/j.forsciint.2004.06.002 (Pubitemid 40082410)