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Volumn 6, Issue 3, 2011, Pages 313-316

The major role of androgens in prostate cancer and the need for more efficient blockade

Author keywords

androgens; antiandrogens; enzyme inhibitors; GnRH agonists; intracrinology; prostate cancer

Indexed keywords

ABIRATERONE; ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTIANDROGEN; BICALUTAMIDE; ESTROGEN; FLUTAMIDE; GONADORELIN AGONIST; NILUTAMIDE; PRASTERONE; PROSTATE SPECIFIC ANTIGEN;

EID: 79956100433     PISSN: 17446651     EISSN: 17448417     Source Type: Journal    
DOI: 10.1586/eem.11.5     Document Type: Review
Times cited : (3)

References (40)
  • 1
    • 79956090845 scopus 로고    scopus 로고
    • Measuring the health impacts of medical innovation and expenditure
    • University of Minnesota, Minneapolis, MN, USA
    • Lichtenberg F. Measuring the health impacts of medical innovation and expenditure. In: Health Services Research Seminal Series 2002-2003. University of Minnesota, Minneapolis, MN, USA (2002).
    • (2002) Health Services Research Seminal Series 2002-2003
    • Lichtenberg, F.1
  • 2
    • 84987481801 scopus 로고
    • Antifertility effects of LHRH agonists in the male
    • Labrie F, Bélanger A, Cusan L, et al. Antifertility effects of LHRH agonists in the male. J. Androl. 1, 209-228 (1980).
    • (1980) J. Androl , vol.1 , pp. 209-228
    • Labrie, F.1    Bélanger, A.2    Cusan, L.3
  • 3
    • 0022169886 scopus 로고
    • Complete androgen blockade for the treatment of prostate cancer
    • Hellman S, Rosenberg SA (Eds) JB Lippincott, PA, USA
    • Labrie F, Dupont A, Bélanger A. Complete androgen blockade for the treatment of prostate cancer. In: Important Advances in Oncology. de Vita VT, Hellman S, Rosenberg SA (Eds). JB Lippincott, PA, USA, 193-217 (1985).
    • (1985) Important Advances in Oncology de Vita VT , pp. 193-217
    • Labrie, F.1    Dupont, A.2    Bélanger, A.3
  • 4
    • 34250862142 scopus 로고    scopus 로고
    • Multiple intracrine hormonal targets in the prostate: Opportunities and challenges
    • DOI 10.1111/j.1464-410X.2007.06955.x
    • Labrie F. Multiple intracrine hormonal targets in the prostate: opportunities and challenges. BJU Int. 100(Suppl. 2), 48-51 (2007). (Pubitemid 46985614)
    • (2007) BJU International , vol.100 , Issue.SUPPL. 2 , pp. 48-51
    • Labrie, F.1
  • 5
    • 79951515767 scopus 로고    scopus 로고
    • Developments to watch. Why did prostate cancer death rates fall?
    • Arnst C. Developments to watch. Why did prostate cancer death rates fall? Business Week 92, 3853 (2003).
    • (2003) Business Week , vol.92 , pp. 3853
    • Arnst, C.1
  • 6
    • 18844408086 scopus 로고    scopus 로고
    • Breast and prostate cancer: 10-year survival gains in the hormonal adjuvant treatment trials
    • (Abstract 32B)
    • Peto R, Dalesio O. Breast and prostate cancer: 10-year survival gains in the hormonal adjuvant treatment trials. Eur. J. Cancer Suppl. 1, S101(Abstract 32B) (2003).
    • (2003) Eur. J. Cancer Suppl , vol.1
    • Peto, R.1    Dalesio, O.2
  • 7
    • 59849125252 scopus 로고    scopus 로고
    • Comparable amounts of sex steroids are made outside the gonads in men and women: Strong lesson for hormone therapy of prostate and breast cancer
    • Labrie F, Cusan L, Gomez JL, et al. Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer. J. Steroid Biochem. Mol. Biol. 113, 52-56 (2009).
    • (2009) J. Steroid Biochem. Mol. Biol , vol.113 , pp. 52-56
    • Labrie, F.1    Cusan, L.2    Gomez, J.L.3
  • 8
    • 0036290334 scopus 로고    scopus 로고
    • Can combined androgen blockade provide long-term control or possible cure of localized prostate cancer?
    • DOI 10.1016/S0090-4295(02)01639-4, PII S0090429502016394
    • Labrie F, Candas B, Gomez JL, Cusan L. Can combined androgen blockade provide long-term control or possible cure of localized prostate cancer? Urology 60(1), 115-119 (2002). (Pubitemid 34722958)
    • (2002) Urology , vol.60 , Issue.1 , pp. 115-119
    • Labrie, F.1    Candas, B.2    Gomez, J.-L.3    Cusan, L.4
  • 10
    • 33751215236 scopus 로고    scopus 로고
    • Efficacy of primary hormonal therapy for patients with localized and locally advanced prostate cancer: A retrospective multicenter study
    • DOI 10.1111/j.1442-2042.2006.01604.x
    • Ueno S, Namiki M, Fukagai T, Ehara H, Usami M, Akaza H. Efficacy of primary hormonal therapy for patients with localized and locally advanced prostate cancer: a retrospective multicenter study. Int. J. Urol. 13(12), 1494-1500 (2006). (Pubitemid 44786336)
    • (2006) International Journal of Urology , vol.13 , Issue.12 , pp. 1494-1500
    • Ueno, S.1    Namiki, M.2    Fukagai, T.3    Ehara, H.4    Usami, M.5    Akaza, H.6
  • 13
    • 0033014347 scopus 로고    scopus 로고
    • Maximum androgen-blockade with medical or surgical castration in advanced prostate cancer: A meta-analysis of nine published randomized controlled trials and 4128 patients using flutamide
    • Bennett CL, Tosteson TD, Schmitt B, Weinberg PD, Ernstoff MS, Ross SD. Maximum androgen-blockade with medical or surgical castration in advanced prostate cancer: a meta-analysis of nine published randomized controlled trials and patients using flutamide. Prostate Cancer Prostatic Dis. 2, 4-8 (1999). (Pubitemid 29096321)
    • (1999) Prostate Cancer and Prostatic Diseases , vol.2 , Issue.1 , pp. 4-8
    • Bennett, C.L.1    Tosteson, T.D.2    Schmitt, B.3    Weinberg, P.D.4    Ernstoff, M.S.5    Ross, S.D.6
  • 14
    • 0034728828 scopus 로고    scopus 로고
    • Maximum androgen blockade in advanced prostate cancer: An overview of the randomised trials
    • Prostate Cancer Triallists' Collaborative Group
    • Prostate Cancer Triallists' Collaborative Group. Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Lancet 355, 1491-1498 (2000).
    • (2000) Lancet , vol.355 , pp. 1491-1498
  • 15
    • 0022574713 scopus 로고
    • A wide range of sensitivities to androgens develops in cloned shionogi mouse mammary tumor cells
    • Labrie F, Veilleux R. A wide range of sensitivities to androgens develops in cloned Shionogi mouse mammary tumor cells. Prostate 8, 293-300 (1986). (Pubitemid 16109155)
    • (1986) Prostate , vol.8 , Issue.3 , pp. 293-300
    • Labrie, F.1    Veilleux, R.2
  • 16
    • 0023907695 scopus 로고
    • Benefits of combination therapy with Flutamide in patients relapsing after castration
    • Labrie F, Dupont A, Giguère M, et al. Benefits of combination therapy with Flutamide in patients relapsing after castration. Br. J. Urol. 61, 341-346 (1988).
    • (1988) Br. J. Urol , vol.61 , pp. 341-346
    • Labrie, F.1    Dupont, A.2    Giguère, M.3
  • 17
    • 0027249588 scopus 로고
    • Response to flutamide withdrawal in advanced prostate cancer in progression under combination therapy
    • Dupont A, Gomez JL, Cusan L, Koutsilieris M, Labrie F. Response to Flutamide withdrawal in advanced prostate cancer in progression under combination therapy. J. Urol. 150, 908-913 (1993). (Pubitemid 23241297)
    • (1993) Journal of Urology , vol.150 , Issue.3 , pp. 908-913
    • Dupont, A.1    Gomez, J.-L.2    Cusan, L.3    Koutsilieris, M.4    Labrie, F.5
  • 19
    • 0027477695 scopus 로고
    • Prostate specific antigen decline after antiandrogen withdrawal: The flutamide withdrawal syndrome
    • Kelly WK, Scher HI. Prostate specific antigen decline after antiandrogen withdrawal: the flutamide withdrawal syndrome. J. Urol. 149, 607-609 (1993). (Pubitemid 23094069)
    • (1993) Journal of Urology , vol.149 , Issue.3 , pp. 607-609
    • Kelly, W.K.1    Scher, H.I.2
  • 20
    • 0023774453 scopus 로고
    • Low androgen levels induce the development of androgen-hypersensitive cells clones in Shionogi mouse mammary carcinoma cells in culture
    • Labrie F, Veilleux R, Fournier A. Low androgen levels induce the development of androgen-hypersensitive cells clones in Shionogi mouse mammary carcinoma cells in culture. J. Natl Cancer Inst. 80, 1138-1147 (1988).
    • (1988) J. Natl Cancer Inst , vol.80 , pp. 1138-1147
    • Labrie, F.1    Veilleux, R.2    Fournier, A.3
  • 22
    • 70249112135 scopus 로고    scopus 로고
    • Measuring therapeutic efficacy in the changing paradigm of castrate-resistant prostate cancer
    • Mulders PF, Schalken JA. Measuring therapeutic efficacy in the changing paradigm of castrate-resistant prostate cancer. Prostate Cancer Prostatic Dis. 12(3), 241-246 (2009).
    • (2009) Prostate Cancer Prostatic Dis , vol.12 , Issue.3 , pp. 241-246
    • Mulders, P.F.1    Schalken, J.A.2
  • 23
    • 42949093654 scopus 로고    scopus 로고
    • Mechanisms of prostate cancer progression to androgen independence
    • DOI 10.1016/j.beem.2008.02.006, PII S1521690X0800033X
    • McPhaul MJ. Mechanisms of prostate cancer progression to androgen independence. Best Pract. Res. Clin. Endocrinol. Metab. 22(2), 373-388 (2008). (Pubitemid 351611961)
    • (2008) Best Practice and Research: Clinical Endocrinology and Metabolism , vol.22 , Issue.2 , pp. 373-388
    • McPhaul, M.J.1
  • 24
    • 0023681542 scopus 로고
    • Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate
    • Labrie C, Bélanger A, Labrie F. Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate. Endocrinology 123, 1412-1417 (1988).
    • (1988) Endocrinology , vol.123 , pp. 1412-1417
    • Labrie, C.1    Bélanger, A.2    Labrie, F.3
  • 25
    • 0032914659 scopus 로고    scopus 로고
    • Localization of type 5 17β-hydroxysteroid dehydrogenase, 3β- hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry
    • El-Alfy M, Luu-The V, Huang XF, Berger L, Labrie F, Pelletier G. Localization of type 5 17b-hydroxysteroid dehydrogenase, 3b-hydroxysteroid dehydrogenase and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry. Endocrinology 140(3), 1481-1491 (1999). (Pubitemid 29104255)
    • (1999) Endocrinology , vol.140 , Issue.3 , pp. 1481-1491
    • El-Alfy, M.1    Luu-The, V.2    Huang, X.-F.3    Berger, L.4    Labrie, F.5    Pelletier, G.6
  • 27
    • 0014659746 scopus 로고
    • In vitro biosynthesis of sterols and steroids by rat submaxillary glands
    • Rosner JM, Macome JC, Cardinali DP. In vitro biosynthesis of sterols and steroids by rat submaxillary glands. Endocrinology 85, 1000-1003 (1969).
    • (1969) Endocrinology , vol.85 , pp. 1000-1003
    • Rosner, J.M.1    MacOme, J.C.2    Cardinali, D.P.3
  • 28
    • 0023025676 scopus 로고
    • Developmental expression of genes for the stereoidogenic enzymes P450scc (20,22-desmolase), P450c17 (17α-hydroxylase/17,20-lyase), and P450c21 (21-hydroxylase) in the human fetus
    • Voutilainen R, Miller WL. Developmental expression of genes for the stereoidogenic enzymes P450scc (20,22-desmolase), P450c17 (17 a-hydroxylase/17,20-lyase), and P450c21 (21-hydroxylase) in the human fetus. J. Clin. Endocrinol. Metab. 63(5), 1145-1150 (1986). (Pubitemid 17173052)
    • (1986) Journal of Clinical Endocrinology and Metabolism , vol.63 , Issue.5 , pp. 1145-1150
    • Voutilainen, R.1    Miller, W.L.2
  • 29
    • 1842863545 scopus 로고    scopus 로고
    • Superior anti-tumor efficacy of bicalutamide 80 mg in combination with a luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist monotherapy as first-line treatment for advanced prostate cancer: Interim results of a randomized study in Japanese patients
    • DOI 10.1093/jjco/hyh001
    • Akaza H, Yamaguchi A, Matsuda T, et al. Superior anti-tumor efficacy of bicalutamide 80 mg in combination with a luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist monotherapy as first-line treatment for advanced prostate cancer: interim results of a randomized study in Japanese patients. Jpn J. Clin. Oncol. 34(1), 20-28 (2004). (Pubitemid 43115330)
    • (2004) Japanese Journal of Clinical Oncology , vol.34 , Issue.1 , pp. 20-28
    • Akaza, H.1    Yamaguchi, A.2    Matsuda, T.3    Igawa, M.4    Kumon, H.5    Soeda, A.6    Arai, Y.7    Usami, M.8    Naito, S.9    Kanetake, H.10    Ohashi, Y.11
  • 32
    • 0030752425 scopus 로고    scopus 로고
    • Estimated potency of Casodex: A problematic design
    • Labrie F, Simard J, Singh SM, Candas B. Estimated potency of Casodex: a problematic design. Urology 50, 309-313 (1997).
    • (1997) Urology , vol.50 , pp. 309-313
    • Labrie, F.1    Simard, J.2    Singh, S.M.3    Candas, B.4
  • 33
    • 4744347762 scopus 로고    scopus 로고
    • Mechanisms of androgen-refractory prostate cancer
    • DOI 10.1056/NEJMp048178
    • Debes JD, Tindall DJ. Mechanisms of androgen-refractory prostate cancer. N. Engl. J. Med. 351(15), 1488-1490 (2004). (Pubitemid 39315314)
    • (2004) New England Journal of Medicine , vol.351 , Issue.15 , pp. 1488-1490
    • Debes, J.D.1    Tindall, D.J.2
  • 34
    • 65649090203 scopus 로고    scopus 로고
    • Development of a second-generation antiandrogen for treatment of advanced prostate cancer
    • Tran C, Ouk S, Clegg NJ, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 324(5928), 787-790 (2009).
    • (2009) Science , vol.324 , Issue.5928 , pp. 787-790
    • Tran, C.1    Ouk, S.2    Clegg, N.J.3
  • 35
    • 77951518711 scopus 로고    scopus 로고
    • Significant and sustained antitumor activity in post-docetaxel, castrationresistant prostate cancer with the CYP17 inhibitor abiraterone acetate
    • Reid AH, Attard G, Danila DC, et al. Significant and sustained antitumor activity in post-docetaxel, castrationresistant prostate cancer with the CYP17 inhibitor abiraterone acetate. J. Clin. Oncol. 28(9), 1489-1495 (2010).
    • (2010) J. Clin. Oncol , vol.28 , Issue.9 , pp. 1489-1495
    • Reid, A.H.1    Attard, G.2    Danila, D.C.3
  • 36
    • 79956065509 scopus 로고    scopus 로고
    • Selective inhibition of CYP17 with abiraterone acetate is highly active incastration-resistant prostate cancer
    • Edinburgh UK September
    • Attard G. Selective inhibition of CYP17 with abiraterone acetate is highly active incastration-resistant prostate cancer. Presented at: 14th International Congress on Hormonal Steroids and Hormones & Cancer. Edinburgh, UK, September 21-24 2010.
    • (2010) 14th International Congress on Hormonal Steroids and Hormones & Cancer , pp. 21-24
    • Attard, G.1
  • 37
    • 77956625246 scopus 로고    scopus 로고
    • Hormonal therapy of prostate cancer
    • Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff DW (Eds). Elsevier, Amsterdam, The Netherlands
    • Labrie F. Hormonal therapy of prostate cancer. In: Neuroendocrinology, The Normal Neuroendocrine System. Progress in Brain Research. Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff DW (Eds). Elsevier, Amsterdam, The Netherlands, 321-341 (2010).
    • (2010) Neuroendocrinology, the Normal Neuroendocrine System. Progress in Brain Research , pp. 321-341
    • Labrie, F.1
  • 39
    • 0029867037 scopus 로고    scopus 로고
    • Diagnosis of advanced or noncurable prostate cancer can be practically eliminated by prostate-specific antigen
    • DOI 10.1016/S0090-4295(99)80419-1
    • Labrie F, Candas B, Cusan L, et al. Diagnosis of advanced or noncurable prostate cancer can be practically eliminated by prostate-specific antigen. Urology 47, 212-217 (1996). (Pubitemid 26075276)
    • (1996) Urology , vol.47 , Issue.2 , pp. 212-217
    • Labrie, F.1    Candas, B.2    Cusan, L.3    Gomez, J.-L.4    Diamond, P.5    Suburu, R.6    Lemay, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.