Chemotherapy-related bilateral dermatitis associated with eccrine squamous syringometaplasia: Reappraisal of epidemiological, clinical, and pathological features

Journal of the American Academy of Dermatology

Volumn 64, Issue 6, 2011, Pages 1092-1103

  Martorell Calatayud, Antonio ^a   Sanmartín, Onofre ^a   Botella Estrada, Rafael ^a   Balmer, Nicole N ^b   Serra Guillén, Carlos ^a   Gomez Moyano, Elisabeth ^c   Traves Zapata, Victor ^a   Requena, Celia ^a   Nagore, Eduardo ^a   Llombart Cussac, Beatriz ^a   Guillen Barona, Carlos ^a  

^a INSTITUTO VALENCIANO DE ONCOLOGÍA   (Spain)

^b University of Alabama at Birmingham   (United States)

^c HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

Author keywords

cytostatic agent; drug reaction; eccrine squamous syringometaplasia; intertriginous rash; oncology; pegylated liposomal doxorubicin

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; BENOXAPROFEN; BUSULFAN; CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; MELPHALAN; METHOTREXATE; MITOXANTRONE; PREDNICARBATE; PREDNISONE; TEMSIROLIMUS; THIOTEPA;

ADULT; AGED; ARTICLE; AXILLA; CELL JUNCTION; CLINICAL ARTICLE; CYTOMEGALOVIRUS INFECTION; DERMATITIS; DESQUAMATION; DRUG ERUPTION; ECCRINE SQUAMOUS SYRINGOMETAPLASIA; ERYTHEMA; FEMALE; HERPES VIRUS INFECTION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERPIGMENTATION; INGUINAL REGION; KERATOACANTHOMA; MALE; METAPLASIA; NECK; PANNICULITIS; PHOTODERMATOSIS; PRIORITY JOURNAL; PYODERMA GANGRENOSUM; RETROSPECTIVE STUDY; SKIN BIOPSY; SKIN EDEMA; SKIN EPITHELIUM; SQUAMOUS CELL CARCINOMA; SYSTEMIC LUPUS ERYTHEMATOSUS; ULCER;

ADOLESCENT; ADULT; AGED; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; AXILLA; CHILD; CYTOSTATIC AGENTS; DERMATITIS; DOXORUBICIN; DRUG ERUPTIONS; ECCRINE GLANDS; FEMALE; GROIN; HUMANS; LIPOSOMES; MALE; MIDDLE AGED; NECK; RETROSPECTIVE STUDIES; SIROLIMUS; YOUNG ADULT;

EID: 79956094941     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2010.04.021     Document Type: Article

References (34)

1. King DT, Barr RJ. Syringometaplasia: mucinous and squamous variants. J Cutan Pathol 1979;6:284-91. (Pubitemid 10226979)
2. Hurt MA, Halvorson RD, Petr FC Jr, Cooper JT Jr, Friedman DJ. Eccrine squamous syringometaplasia: a cutaneous sweat gland reaction in the histologic spectrum of 'chemotherapy-associated eccrine hidradenitis' and 'neutrophilic eccrine hidradenitis'. Arch Dermatol 1990;126:73-7.
3. Serrano T, Saez A, Moreno A. Eccrine squamous syringometaplasia: a prospective clinicopathologic study. J Cutan Pathol 1993;20:61-5. (Pubitemid 23092873)
4. El Darouti MA, Marzouk SA, El Hadidi HA, Sobhi RM. Eccrine syringosquamous metaplasia. Int J Dermatol 2001;40:777-81. (Pubitemid 34051447)
5. Garcia-Navarro X, Puig L, Fernandez-Figueras MT, Alomar A. Eccrine squamous syringometaplasia secondary to pegylated liposomal doxorubicin. Arch Dermatol 2008;144:1402-3.
6. Valks R, Fraga J, Porras-Luque J, Figuera A, Garcia-Diez A, Fernandez-Herrera J. Chemotherapy-induced eccrine squamous syringometaplasia: a distinctive eruption in patients receiving hematopoietic progenitor cells. Arch Dermatol 1997;133:873-8. (Pubitemid 27337548)
7. Prussick R. Adverse cutaneous reactions to chemotherapeutic agents and cytokine therapy. Semin Cutan Med Surg 1996;15:267-76. (Pubitemid 27197966)
8. Bolognia JL, Cooper DL, Glusac EJ. Toxic erythema of chemotherapy: a useful clinical term. J Am Acad Dermatol 2008;59:524-9.
9. Heidary N, Naik H, Burgin S. Chemotherapeutic agents and the skin: an update. J Am Acad Dermatol 2008;58:545-70. (Pubitemid 351375051)
10. Rongioletti F, Ballestrero A, Bogliolo F, Rebora A. Necrotizing eccrine squamous syringometaplasia presenting as acral erythema. J Cutan Pathol 1991;18:453-6.
11. Tsuboi H, Yonemoto K, Katsuoka K. A case of bleomycin-induced acral erythema (AE) with eccrine squamous syringometaplasia (ESS) and summary of reports of AE with ESS in the literature. J Dermatol 2005;32:921-5. (Pubitemid 43002078)
12. Bordel MT, Miranda A. Eccrine squamous syringometaplasia from chemotherapy extravasation. Actas Dermo-Sif 2005;96:462-4. (Pubitemid 41512531)
13. Rios-Buceta L, Penas PF, Dauden-Tello E, Fraga-Fernandez J, Dominguez-Arciniega P, Garcia-Diez A. Recall phenomenon with the unusual presence of eccrine squamous syringometaplasia. Br J Dermatol 1995;133:630-2.
14. Jerasutus S, Laohabha K, Suvanprakorn P. Primary squamous syringometaplasia with no underlying malignancy. Int J Dermatol 1999;38:375-6. (Pubitemid 29258123)
15. Baysse L, Boralevi F, Lepreux S, Boyer A, Morel C, Léauté- Labrèze C, et al. Eccrine squamous syringometaplasia and cytomegalovirus infection. Rev Med Interne 2003;24:394-8. (Pubitemid 36781216)
16. Dauden E, Porras JI, Buezo GF, Garcia-Diez A. Eccrine squamous syringometaplasia and cytomegalovirus. Am J Dermatopathol 2000;22:559-61.
17. Chetty R, Bramdev A, Govender D. Cytomegalovirus-induced syringosquamous metaplasia. Am J Dermatopathol 1999;21:487-90. (Pubitemid 29491280)
18. Alonso V, Ramon D, Monteagudo C, Llombart B, Martin JM, Jorda E. Eccrine squamous syringometaplasia mimicking a herpetic infection. Int J Dermatol 2006;45:762-3. (Pubitemid 44056686)
19. Choi SW, Yang JE, Kang SJ, Lee HR, Kim CW. Herpetic infection on the vulva associated with eccrine squamous syringometaplasia in malignant lymphoma. Acta Derm Venereol 1999;79:500-1.
20. Muñoz E, Valks R, Fernandez-Herrera J, Fraga J. Herpetic syringitis associated with eccrine squamous syringometaplasia in HIV-positive patients. J Cutan Pathol 1997;24:425-8. (Pubitemid 27374504)
21. Lerner TH, Barr RJ, Dolezal JF, Stagnone JJ. Syringomatous hyperplasia and eccrine squamous syringometaplasia associated with benoxaprofen therapy. Arch Dermatol 1987;123:1202-4.
22. Vargas-Diez E, Valks R, Fraga J, Fernandez-Herrera J, Garcia-Diez A. Eccrine squamous syringometaplasia in a patient with phytophotodermatosis. Int J Dermatol 1998;37:715-7. (Pubitemid 28428331)
23. Metcalf JS, Maize JC. Squamous syringometaplasia in lobular panniculitis and pyoderma gangrenosum. Am J Dermatopathol 1990;12:141-9. (Pubitemid 20122147)
24. Helton JL, Metcalf JS. Squamous syringometaplasia in association with annular elastolytic granuloma. Am J Dermatopathol 1995;17:407-9.
25. Garcia-Rio I, Perez-Gala S, Fraga J, Garcia-Diez A, Fernandez-Herrera J. Eccrine squamous syringometaplasia in a patient with systemic lupus erythematosus. J Eur Acad Dermatol Venereol 2006;20:608-10.
26. Sakai H, Satoh K, Manabe A, Nakane H, Ishida-Yamamoto A, Iizuka H. Eccrine squamous syringometaplasia and syringomatous hyperplasia in association with linear scleroderma. Dermatology 2002;204:136-8. (Pubitemid 34297979)
27. Sommer B, Hagedorn M, Wood F, Heenan P. Eccrine squamous syringometaplasia in the skin of children after burns. J Cutan Pathol 1998;25:56-8. (Pubitemid 28059596)
28. Sheen YS, Huang CL, Chu CY. Eccrine squamous syringometaplasia associated with sunitinib therapy. J Eur Acad Dermatol Venereol 2007;21:1136-7.
29. Van de Voorde K, De Raeve H, Van Regenmortel N, Lambert J. Imatinib-induced eccrine squamous syringometaplasia. J Am Acad Dermatol 2006;55(Suppl):S58-9.
30. Bhawan J, Malhotra R. Syringosquamous metaplasia: a distinctive eruption in patients receiving chemotherapy. Am J Dermatopathol 1990;12:1-6. (Pubitemid 20060396)
31. Karam A, Metges JP, Labat JP, Leroy JP, Guillet G. Squamous syringometaplasia associated with docetaxel. Br J Dermatol 2002;146:524-5.
32. Thomas LM, Mohr M, Smith M, Boyd A. Vincristine-induced eccrine squamous syringometaplasia 2008;25:623-5.
33. Johnson HL, Maibach HI. Drug excretion in human eccrine sweat. J Invest Dermatol 1971;56:182-8.
34. Jacobi U, Waibler E, Schulze P, Sehouli J, Oskay-Ozcelik G, Schmook T, et al. Release of doxorubicin in sweat: first step to induce the palmar-plantar erythrodysesthesia syndrome? Ann Oncol 2005;16:1210-1.