High-sensitivity cardiac troponin for screening large populations of healthy people: Is there risk?

Clinical Chemistry

Volumn 57, Issue 4, 2011, Pages 537-539

  Apple, Fred S ^a,b  

^a HENNEPIN COUNTY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CREATINE KINASE MB; TROPONIN; TROPONIN T;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; CARDIOVASCULAR RISK; CLINICAL PRACTICE; DISEASE SURVEILLANCE; EARLY INTERVENTION; FOOD AND DRUG ADMINISTRATION; HAZARD RATIO; HEART FAILURE; HUMAN; IMMUNOASSAY; LABORATORY TEST; MORTALITY; POPULATION RESEARCH; PREDICTIVE VALUE; PRIMARY PREVENTION; PROTEIN ANALYSIS; REFERENCE VALUE; RISK ASSESSMENT; SCREENING; SHORT SURVEY;

BIOLOGICAL MARKERS; HUMANS; MASS SCREENING; MYOCARDIAL INFARCTION; REFERENCE VALUES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TROPONIN T;

EID: 79956079610     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2011.162875     Document Type: Short Survey

References (6)

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3. deFilippi CR, de Lemos JA, Christenson RH, Gottdiener JS, Kop WJ, Zhan M, Seliger SL. Association of serial measurement of cardiac troponin T using a sensitive assay with incident heart failure and cardiovascular mortality in older adults. JAMA 2010;304:2494-502.
4. de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA 2010;304:2503-12.
5. Blankenberg S, Zeller T, Saarela O, Havulinna AS, Kee F, Tunstall-Pedoe H, et al. Contributions of 30 biomarkers to 10-year cardiovascular risk estimation in 2 population cohorts: the MONICA, Risk Genetics, Archiving, and Monograph (MORGAM) Biomarker Project. Circulation 2010;121:2388-97.
6. Apple FS, Steffen LM, Pearce LA, Murakami MM, Luepker RV. Multiple biomarkers for prediction of cardiovascular death within the Minnesota Heart Survey [Abstract 17337]. Circulation 2010; 122(Suppl):23.