Voxelwise assessment of the regional distribution of damage in the brains of patients with multiple sclerosis and fatigue

American Journal of Neuroradiology

Volumn 32, Issue 5, 2011, Pages 874-879

  Riccitelli, G ^a   Rocca, M A ^a   Forn, C ^a,b   Colombo, B ^a   Comi, G ^a   Filippi, Massimo ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITAT JAUME I   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN ATROPHY; BRAIN DAMAGE; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS CALLOSUM; DIFFUSION WEIGHTED IMAGING; FATIGUE; FEMALE; FRONTAL GYRUS; GRAY MATTER; HUMAN; MALE; MULTIPLE SCLEROSIS; POSTERIOR CINGULATE; PRIMARY MOTOR CORTEX; THALAMUS; VOXEL BASED MORPHOMETRY; WHITE MATTER;

ADULT; BRAIN; ECHO-PLANAR IMAGING; FATIGUE; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; SENSITIVITY AND SPECIFICITY;

EID: 79956076480     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A2412     Document Type: Article

References (34)

1. Chaudhuri A, Behan PO. Fatigue in neurological disorders. Lancet 2004;363:978-88 (Pubitemid 38388334)
2. DeLuca J, Genova HM, Capili EJ, et al. Functional neuroimaging of fatigue. Phys Med Rehabil Clin N Am 2009;20:325-37
3. Leocani L, Colombo B, Comi G. Physiopathology of fatigue in multiple sclerosis. Neurol Sci 2008;29(suppl 2):S241-43
4. Mainero C, Faroni J, Gasperini C, et al. Fatigue and magnetic resonance imaging activity in multiple sclerosis. J Neurol 1999;246:454-58 (Pubitemid 29326839)
5. Bakshi R, Miletich RS, Henschel K, et al. Fatigue in multiple sclerosis: cross-sectional correlation with brain MRI findings in 71 patients. Neurology 1999;53:1151-53 (Pubitemid 29442146)
6. Codella M, Rocca MA, Colombo B, et al. A preliminary study of magnetization transfer and diffusion tensor MRI of multiple sclerosis patients with fatigue. J Neurol 2002;249:535-37 (Pubitemid 34507825)
7. Codella M, Rocca MA, Colombo B, et al. Cerebral grey matter pathology and fatigue in patients with multiple sclerosis: a preliminary study. J Neurol Sci 2002;194:71-74 (Pubitemid 34051558)
8. Roelcke U, Kappos L, Lechner-Scott J, et al. Reduced glucose metabolism in the frontal cortex and basal ganglia of multiple sclerosis patients with fatigue: a 18F-fluorodeoxyglucose positron emission tomography study. Neurology 1997;48:1566-71
9. Filippi M, Rocca MA, Colombo B, et al. Functional magnetic resonance imaging correlates of fatigue in multiple sclerosis. Neuroimage 2002;15:559-67 (Pubitemid 34852523)
10. Rocca MA, Filippi M. Functional MRI in multiple sclerosis. J Neuroimaging 2007;17(suppl 1):36S- 41S
11. Tartaglia MC, Narayanan S, Arnold DL. Mental fatigue alters the pattern and increases the volume of cerebral activation required for a motor task in multiple sclerosis patients with fatigue. Eur J Neurol 2008;15:413-19 (Pubitemid 351422398)
12. DeLuca J, Genova HM, Hillary FG, et al. Neural correlates of cognitive fatigue in multiple sclerosis using functional MRI. J Neurol Sci 2008;270:28-39
13. Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey - National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 1996;46:907-11
14. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979;134:382-89 (Pubitemid 9136500)
15. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-52 (Pubitemid 14237132)
16. Krupp LB, LaRocca NG, Muir-Nash J, et al. The fatigue severity scale: application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 1989;46:1121-23 (Pubitemid 19246303)
17. Smith SM, Zhang Y, Jenkinson M, et al. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage 2002;17:479-89
18. Ashburner J, Friston KJ. Unified segmentation. Neuroimage 2005;26:839-51 (Pubitemid 40825026)
19. Ashburner J. A fast diffeomorphic image registration algorithm. Neuroimage 2007;38:95-113. Epub 2007 Jul 18 (Pubitemid 47440133)
20. Colombo B, Martinelli Boneschi F, Rossi P, et al. MRI and motor evoked potential findings in nondisabled multiple sclerosis patients with and without symptoms of fatigue. J Neurol 2000;247:506-09 (Pubitemid 30598875)
21. Tedeschi G, Dinacci D, Lavorgna L, et al. Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability. J Neurol Sci 2007;263:15-19 (Pubitemid 350029853)
22. Miller DH, Barkhof F, Frank JA, et al. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain 2002;125:1676-95
23. Marrie RA, Fisher E, Miller DM, et al. Association of fatigue and brain atrophy in multiple sclerosis. J Neurol Sci 2005;228:161-66 (Pubitemid 40202962)
24. Audoin B, Davies GR, Finisku L, et al. Localization of grey matter atrophy in early RRMS: a longitudinal study. J Neurol 2006;253:1495-501 (Pubitemid 44950285)
25. Prinster A, Quarantelli M, Orefice G, et al. Grey matter loss in relapsing-remitting multiple sclerosis: a voxel-based morphometry study. Neuroimage 2006;29:859-67 (Pubitemid 43121211)
26. Ceccarelli A, Rocca MA, Pagani E, et al. A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes. Neuroimage 2008;42:315-22
27. Mesaros S, Rocca MA, Absinta M, et al. Evidence of thalamic gray matter loss in pediatric multiple sclerosis. Neurology 2008;70:1107-12 (Pubitemid 351464767)
28. Sepulcre J, Sastre-Garriga J, Cercignani M, et al. Regional gray matter atrophy in early primary progressive multiple sclerosis: a voxel-based morphometry study. Arch Neurol 2006;63:1175-80 (Pubitemid 44232328)
29. Leocani L, Colombo B, Magnani G, et al. Fatigue in multiple sclerosis is associated with abnormal cortical activation to voluntary movement: EEG evidence. Neuroimage 2001;13:1186-92 (Pubitemid 32553549)
30. Sepulcre J, Masdeu JC, Goni J, et al. Fatigue in multiple sclerosis is associated with the disruption of frontal and parietal pathways. Mult Scler 2009;15:337-44
31. Okada T, Tanaka M, Kuratsune H, et al. Mechanisms underlying fatigue: a voxel-based morphometric study of chronic fatigue syndrome. BMC Neurol 2004;4:14
32. Calabrese M, Agosta F, Rinaldi F, et al. Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis. Arch Neurol 2009;66:1144-50
33. Calabrese M, Rocca M, Atzori M, et al. A three-year MRI study of cortical lesions in relapse-onset multiple sclerosis. Ann Neurol 2010;67:376-83
34. Chaudhuri A, Behan PO. Fatigue and basal ganglia. J Neurol Sci 2000;179: 34-42