Hospital-reported data on the pneumonia quality measure "time to first antibiotic dose" are not associated with inpatient mortality: Results of a nationwide cross-sectional analysis

Academic Emergency Medicine

Volumn 18, Issue 5, 2011, Pages 496-503

  Quattromani, Erin ^a   Powell, Emilie S ^a,b   Khare, Rahul K ^a,b   Cheema, Navneet ^a   Sauser, Kori ^a   Periyanayagam, Usha ^a   Pirotte, Matthew J ^a   Feinglass, Joe ^b   Mark Courtney, D ^a  

^a Department of Emergency Medicine ^*  (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

AGED; ARTICLE; COMORBIDITY; EMERGENCY WARD; FEMALE; GEOGRAPHIC ORIGIN; HEALTH CARE QUALITY; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; INCOME; MAJOR CLINICAL STUDY; MALE; MEDICAID; MORTALITY; PNEUMONIA; POPULATION RESEARCH; PRIORITY JOURNAL; RISK ASSESSMENT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANTI-BACTERIAL AGENTS; CAUSE OF DEATH; COMORBIDITY; CROSS-SECTIONAL STUDIES; EMERGENCY SERVICE, HOSPITAL; FEMALE; HOSPITAL MORTALITY; HUMANS; LOGISTIC MODELS; MALE; MEDICARE; MIDDLE AGED; PNEUMONIA; PROCESS ASSESSMENT (HEALTH CARE); QUALITY INDICATORS, HEALTH CARE; TIME FACTORS; UNITED STATES; YOUNG ADULT;

EID: 79956075704     PISSN: 10696563     EISSN: 15532712     Source Type: Journal    
DOI: 10.1111/j.1553-2712.2011.01053.x     Document Type: Article

References (40)

1. Centers for Disease Control and Prevention. FastStats: Death and Mortality. Available at http://cdc.gov/nchs/fastats/deaths.htm. Accessed Mar 3, 2011.
2. Heron M, Hoyert DL, Murphy SL, et al., Deaths: final data for 2006. Natl Vital Stat Rep. 2009; 57: 1-134.
3. Lave JR,. The cost of treating patients with community-acquired pneumonia. Semin Respir Crit Care Med. 1999; 20: 189-97. (Pubitemid 29277759)
4. Stanton M,. Improving Treatment Decisions for Patients with Community-Acquired Pneumonia. Available at: http://www.ahrq.gov/clinic/ pneumonia/pneumonria.htm. Accessed Mar 3, 2011.
5. Pitts SR, Niska RW, Xu J, Burt CW,. National Hospital Ambulatory Medical Care Survey: 2006 emergency department summary. Natl Health Stat Report. 2008: 1-38.
6. U.S. Department of Health and Human Services. Hospital Compare Home. Available at: http://www.hospitalcompare.hhs.gov/. Accessed Mar 3, 2011.
7. The Joint Commission. Performance Measure Initiatives: Pneumonia Core Measure Set. Available at: http://www.jointcommission.org/assets/1/6/Pneumonia. pdf. Accessed Mar 3, 2011.
8. Kanwar M, Brar N, Khatib R, Fakih MG,. Misdiagnosis of community-acquired pneumonia and inappropriate utilization of antibiotics: side effects of the 4-h antibiotic administration rule. Chest. 2007; 131: 1865-9. (Pubitemid 46981647)
9. Wachter RM, Flanders SA, Fee C, Pronovost PJ,. Public reporting of antibiotic timing in patients with pneumonia: lessons from a flawed performance measure. Ann Intern Med. 2008; 149: 29-32.
10. Yu KT, Wyer PC,. Evidence-based emergency medicine/critically appraised topic. Evidence behind the 4-hour rule for initiation of antibiotic therapy in community-acquired pneumonia. Ann Emerg Med. 2008; 51: 651-62.
11. Pines JM, Isserman JA, Hinfey PB,. The measurement of time to first antibiotic dose for pneumonia in the emergency department: a white paper and position statement prepared for the American Academy of Emergency Medicine. J Emerg Med. 2009; 37: 335-40.
12. Houck PM, Bratzler DW, Nsa W, Ma A, Bartlett JG,. Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia. Arch Intern Med. 2004; 164: 637-44. (Pubitemid 38392978)
13. Meehan TP, Fine MJ, Krumholz HM, et al., Quality of care, process, and outcomes in elderly patients with pneumonia. JAMA. 1997; 278: 2080-4. (Pubitemid 28016230)
14. Dedier J, Singer DE, Chang Y, Moore M, Atlas SJ,. Processes of care, illness severity, and outcomes in the management of community-acquired pneumonia at academic hospitals. Arch Intern Med. 2001; 161: 2099-104.
15. Marrie TJ, Wu L,. Factors influencing in-hospital mortality in community-acquired pneumonia: a prospective study of patients not initially admitted to the ICU. Chest. 2005; 127: 1260-70. (Pubitemid 46224289)
16. Silber SH, Garrett C, Singh R, et al., Early administration of antibiotics does not shorten time to clinical stability in patients with moderate-to-severe community-acquired pneumonia. Chest. 2003; 124: 1798-804. (Pubitemid 37433575)
17. Drake DE, Cohen A, Cohn J,. National hospital antibiotic timing measures for pneumonia and antibiotic overuse. Qual Manag Health Care. 2007; 16: 113-22.
18. Fee C, Weber E, Sharpe BA, Nguy M, Quon T, Bookwalter T,. JCAHO/CMS core measures for community-acquired pneumonia [letter]. Ann Emerg Med. 2006; 47: 505.
19. Fee C, Weber EJ,. Identification of 90% of patients ultimately diagnosed with community-acquired pneumonia within four hours of emergency department arrival may not be feasible. Ann Emerg Med. 2007; 49: 553-9. (Pubitemid 46601693)
20. Nicks BA, Manthey DE, Fitch MT,. The Centers for Medicare and Medicaid Services (CMS) community-acquired pneumonia core measures lead to unnecessary antibiotic administration by emergency physicians. Acad Emerg Med. 2009; 16: 184-87.
21. Pines JM,. Profiles in patient safety: Antibiotic timing in pneumonia and pay-for-performance. Acad Emerg Med. 2006; 13: 787-90. (Pubitemid 43928653)
22. Pines JM, Hollander JE, Lee H, Everett WW, Uscher-Pines L, Metlay JP,. Emergency department operational changes in response to pay-for-performance and antibiotic timing in pneumonia. Acad Emerg Med. 2007; 14: 545-8. (Pubitemid 46778893)
23. Welker JA, Huston M, McCue JD,. Antibiotic timing and errors in diagnosing pneumonia. Arch Intern Med. 2008; 168: 351-6. (Pubitemid 351347125)
24. Hausmann LR, Ibrahim SA, Mehrotra A, et al., Racial and ethnic disparities in pneumonia treatment and mortality. Med Care. 2009; 47: 1009-17.
25. Elixhauser A, Steiner C, Harris DR, Coffey RM,. Comorbidity measures for use with administrative data. Med Care. 1998; 36: 8-27. (Pubitemid 128456396)
26. Chu YT, Ng YY, Wu SC,. Comparison of different comorbidity measures for use with administrative data in predicting short- and long-term mortality. BMC Health Serv Res. 2010; 10: e140.
27. Southern DA, Quan H, Ghali WA,. Comparison of the Elixhauser and Charlson/Deyo methods of comorbidity measurement in administrative data. Med Care. 2004; 42: 355-60.
28. Zeger S, Liang K,. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986; 42: 121-30.
29. Cheng AC, Buising KL,. Delayed administration of antibiotics and mortality in patients with community-acquired pneumonia. Ann Emerg Med. 2009; 53: 618-24.
30. Waterer GW, Kessler LA, Wunderink RG,. Delayed administration of antibiotics and atypical presentation in community-acquired pneumonia. Chest. 2006; 130: 11-5. (Pubitemid 44116836)
31. Metlay JP, Schulz R, Li YH, et al., Influence of age on symptoms at presentation in patients with community-acquired pneumonia. Arch Intern Med. 1997; 157: 1453-9. (Pubitemid 27300393)
32. Bodi M, Rodriguez A, Sole-Violan J, et al., Antibiotic prescription for community-acquired pneumonia in the intensive care unit: impact of adherence to Infectious Diseases Society of America guidelines on survival. Clin Infect Dis. 2005; 41: 1709-16. (Pubitemid 41759852)
33. Jha AK, Li Z, Orav EJ, et al., Care in U.S. hospitals - the Hospital Quality Alliance program. N Engl J Med. 2005; 353: 265-74. (Pubitemid 41058326)
34. Fine JM, Fine MJ, Galusha D, Petrillo M, Meehan TP,. Patient and hospital characteristics associated with recommended processes of care for elderly patients hospitalized with pneumonia: results from the medicare quality indicator system pneumonia module. Arch Intern Med. 2002; 162: 827-33. (Pubitemid 34273308)
35. Ayanian JZ, Weissman JS, Chasan-Taber S, Epstein AM,. Quality of care by race and gender for congestive heart failure and pneumonia. Med Care. 1999; 37: 1260-9.
36. Camp PG, O'Donnell DE, Postma DS,. Chronic obstructive pulmonary disease in men and women: myths and reality. Proc Am Thorac Soc. 2009; 6: 535-8.
37. Ziss DR, Stowers A, Feild C,. Community-acquired pneumonia: compliance with centers for Medicare and Medicaid services, national guidelines, and factors associated with outcome. South Med J. 2003; 96: 949-59. (Pubitemid 38281662)
38. Meehan TP, Weingarten SR, Holmboe ES, et al., A statewide initiative to improve the care of hospitalized pneumonia patients: The Connecticut Pneumonia Pathway Project. Am J Med 2001; 111: 203-10. (Pubitemid 32786948)
39. Centers for Disease Control and Prevention. ICD-9-CM Official Guidelines for Coding and Reporting. Available at: http://www.cdc.gov/nchs/data/icd9/ icdguide09.pdf. Accessed Mar 2, 2011.
40. Fine MJ, Auble TE, Yealy DM, et al., A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med. 1997; 336: 243-50. (Pubitemid 27044625)