High sensitivity of a histological method in the detection of low-dosage illicit treatment with 17β-estradiol in male calves

Food Control

Volumn 22, Issue 10, 2011, Pages 1668-1673

  Pezzolato, M ^a   Maurella, C ^a   Varello, K ^a   Meloni, D ^a   Bellino, C ^b   Borlatto, L ^a   Di Corcia, D ^c   Capra, P ^a   Caramelli, M ^a   Bozzetta, E ^a  

^a LIGURIA E VALLE D AOSTA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c Centro Regionale Antidoping A Bertinaria   (Italy)

Author keywords

17 Estradiol; Histopathology; Screening method; Veal calves

Indexed keywords

ANIMALIA;

EID: 79956065275     PISSN: 09567135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodcont.2011.03.027     Document Type: Article

References (23)

1. Bovee T.F., Bor G., Heskamp H.H., Lasaroms J.J., Sanders M.B., Nielen M.W. Validation and application of a yeast bioassay for screening androgenic activity in calf urine and feed. Analytica Chimica Acta 2009, 637:225-234.
2. Cai J., Henion J. Quantitative multi-residue determination of beta-agonists in bovine urine using on-line immunoaffinity extraction-coupled column packed capillary liquid chromatography-tandem mass spectrometry. Journal of Chromatography B Biomedical Sciences and Applications 1997, 691:357-370.
3. Groot M.J., Biolatti B. Histopathological effects of boldenone in cattle. Journal of Veterinary Medicine A: Physiology Pathology Clinical Medicine 2004, 51:58-63.
4. Groot M.J., Ossenkoppele J.S., Bakker R., Pfaffl M.W., Meyer H.H., Nielen M.W. Reference histology of veal calf genital and endocrine tissues - an update for screening on hormonal growth promoters. Journal of Veterinary Medicine A: Physiology Pathology Clinical Medicine 2007, 54:238-246.
5. Groot M.J., Schilt R., Ossenkoppele J.S., Berende P.L., Haasnoot W. Combinations of growth promoters in veal calves: consequences for screening and confirmation methods. Zentralblatt fur Veterinarmedizin A 1998, 45:425-440.
6. Guarda F., Biolatti B., Miglietti M. Pathologico-anatomic findings in thymus gland and female sex organs of slaughtered calves after treatment with anabolically effective substances. Dtsche Tierarztliche Wochenschrift 1990, 97:313-315.
7. Hewitt S.A., Kearney M., Currie J.W., Young P.B., Kennedy D.G. Screening and confirmatory strategies for the surveillance of anabolic steroid abuse within Northern Ireland. Analytica Chimica Acta 2002, 473:99-109.
8. Kroes R., Berkvens J.M., Loendersloot H.J., Ruitenberg E.J. Oestrogen-induced changes in the genital tract of the male calf. Zentralblatt fur Veterinarmedizin A 1971, 18:717-730.
9. Ministerial Decree 14 November Determinazione dei livelli fisiologici massimi degli ormoni sessuali di natura endogena estradiolo 17 beta, progesterone e testosterone nel siero o nel plasma di sangue bovino. Italian Official Journal 1996, 24. 30 January 1997.
10. Meyer H.H. Biochemistry and physiology of anabolic hormones used for improvement of meat production. APMIS 2001, 109:1-8.
11. Meyer H.H., Sauerwein H., Mutayoba B.M. Immunoaffinity chromatography and a biotin-streptavidin amplified enzymeimmunoassay for sensitive and specific estimation of estradiol-17 beta. Journal of Steroid Biochemistry 1990, 35:263-269.
12. Meyer H.H.D., Stoffel B., Hagen-Mann K. Ruminant physiology: Digestion, metabolism, growth and reproduction. Proc.of the eight international symposium on ruminant physiology 1995, 475-482. Ferdinand Enke Verlag, Stuttgart. W. von Engelhardt, S. Leonhard-Marek, G. Breves, D. Giesecke (Eds.).
13. Nebbia C. Residui di farmaci e contaminanti ambientali nelle produzioni animali 2009, EdiSES, (charter 15).
14. Noppe H., Le Bizec B., Verheyden K., De Brabander H.F. Novel analytical methods for the determination of steroid hormones in edible matrices. Analitica Chimica Acta 2008, 611:1-16.
15. Sauerwein H., Pfaffl M., Hagen-Mann K., Malucelli A., Meyer H.H. Expression of estrogen and androgen receptor in the bovine gastrointestinal tract. Dtsche Tierarztliche Wochenschrift 1995, 102:143-178.
16. Schilt R., Groot M.J., Berende P.L., Ramazza V., Ossenkoppele J.S., Haasnoot W., et al. Pour on application of growth promoters in veal calves: analytical and histological results. Analyst 1998, 123:2665-2670.
17. Smith J.L., Wilson L.L., Swanson D.L. Implant sequence effects in intact male Holstein veal calves: live and slaughter traits. Journal of Animal Science 1999, 77:3125-3132.
18. The Commission of the European Communities Council directive 96/23/EC on measures to monitor certain substances and residues thereof in live animals and animal products and repealing directives 85/358/EEC and 86/496/EEC and decisions 89/187/EEC and 91/664/EEC. Official Journal of the European Communities 1996, L125:10-32.
19. The Commission of the European Communities Commission decision 2002/657/EC implementing council directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Official Journal of the European Union 2002, L221:8-36.
20. The Council of the European Union Council directive 96/22/EC concerning the prohibition on the use of stockfarming of certain substances having a hormonal or thyrostatic action and beta-agonists, and replacing directives 81/602/EEC, 88/146/EEC and 88/299/EEC. Official Journal of the European Communities 1996, L125:3-8.
21. The European Parliament and the Council of the European Union European parliament and council directive 2008/97/EC amending council directive 96/22/EC concerning the prohibition on the use in stockfarming of certain substances having a hormonal or thyrostatic action and of beta-agonists. Official Journal of the European Union 2002, L318:9-11.
22. Van Poucke C., Van Peteghem C. Development and validation of a multi-analyte method for the detection of anabolic steroids in bovine urine with liquid chromatography-tandem mass spectrometry. Journal of Chromatography B: Analytical Technologies in The Biomedical and Life Science 2002, 772:211-217.
23. Weijman J., Zwart P., Vos J.G., Ramaekers F.C. Immunohistochemical method for detecting lesions in the prostate gland of bulls treated with diethylstilbestrol-dipropionate. Veterinary Record 1996, 139:515-519.