Genetic variability in serotonin receptor and transporter genes may influence risk for tardive dyskinesia in chronic schizophrenia

Psychiatry Research

Volumn 188, Issue 1, 2011, Pages 175-176

  Hsieh, Ching Jow ^a   Chen, Yen Ching ^b   Lai, Mei Shu ^b   Hong, Chen Jee ^c   Chien, Kuo Liong ^a  

^a Yuanshan Veterans Hospital   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROLEPTIC AGENT; SEROTONIN 2A RECEPTOR; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER;

ABNORMAL INVOLUNTARY MOVEMENT SCALE; ADULT; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; EXTRAPYRAMIDAL SYMPTOM RATING SCALE; FEMALE; GENE; GENE FREQUENCY; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HTR2A GENE; HUMAN; LETTER; MALE; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; SCHIZOPHRENIA; TAIWAN; TARDIVE DYSKINESIA;

ANTIPSYCHOTIC AGENTS; CYSTEINE; DISEASE SUSCEPTIBILITY; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MOVEMENT DISORDERS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, SEROTONIN, 5-HT3; RISK FACTORS; SCHIZOPHRENIA; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TAIWAN; THREONINE;

EID: 79956050690     PISSN: 01651781     EISSN: 01651781     Source Type: Journal    
DOI: 10.1016/j.psychres.2010.10.006     Document Type: Letter

References (5)

1. Basile V.S., Ozdemir V., Masellis M., Meltzer H.Y., Lieberman J.A., Potkin S.G., Macciardi F.M., Petronis A., Kennedy J.L. Lack of association between serotonin-2A receptor gene (HTR2A) polymorphisms and tardive dyskinesia in schizophrenia. Molecular Psychiatry 2001, 6(2):230-234.
2. Deshpande S.N., Varma P.G., Semwal P., Rao A.R., Bhatia T., Nimgaonkar V.L., Lerer B., Thelma B.K. II. Serotonin receptor gene polymorphisms and their association with tardive dyskinesia among schizophrenia patients from North India. Psychiatric Genetics 2005, 15(3):157-158.
3. Herken H., Erdal M.E., Boke O., Savas H.A. Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene. European Psychiatry 2003, 18(2):77-81.
4. Segman R.H., Heresco-Levy U., Finkel B., Goltser T., Shalem R., Schlafman M., Dorevitch A., Yakir A., Greenberg D., Lerner A., Lerer B. Association between the serotonin 2A receptor gene and tardive dyskinesia in chronic schizophrenia. Molecular Psychiatry 2001, 6(2):225-229.
5. Tan E.C., Chong S.A., Mahendran R., Dong F., Tan C.H. Susceptibility to neuroleptic-induced tardive dyskinesia and the T102C polymorphism in the serotonin type 2A receptor. Biological Psychiatry 2001, 50(2):144-147.