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Volumn 33, Issue 3, 2011, Pages 330-345

Iloperidone for the Management of Adults with Schizophrenia

Author keywords

Antipsychotic drugs; Iloperidone; Schizophrenia; Second generation antipsychotics

Indexed keywords

AMIODARONE; ANTIHYPERTENSIVE AGENT; APOMORPHINE; CARBAMAZEPINE; CHLORPROMAZINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CIRAZOLINE; FLUOXETINE; HALOPERIDOL; ILOPERIDONE; KETOCONAZOLE; OLANZAPINE; PAROXETINE; PHENCYCLIDINE; PLACEBO; PRAZOSIN; PROCAINAMIDE; RISPERIDONE; TERAZOSIN; THIORIDAZINE; ZIPRASIDONE;

EID: 79956044939     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2011.03.006     Document Type: Article
Times cited : (16)

References (33)
  • 1
    • 34047224453 scopus 로고    scopus 로고
    • Suicide risk in schizophrenia: learning from the past to change the future
    • Pompili M., Amador X.F., Girardi P., et al. Suicide risk in schizophrenia: learning from the past to change the future. Ann Gen Psychiatry 2007, 6:10.
    • (2007) Ann Gen Psychiatry , vol.6 , pp. 10
    • Pompili, M.1    Amador, X.F.2    Girardi, P.3
  • 2
    • 0027510643 scopus 로고
    • The de facto mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services
    • Regier D.A., Narrow W.E., Rae D.S., et al. The de facto mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. Arch Gen Psychiatry 1993, 50:85-94.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 85-94
    • Regier, D.A.1    Narrow, W.E.2    Rae, D.S.3
  • 3
    • 0027192157 scopus 로고
    • The costs of schizophrenia. Assessing the burden
    • Rupp A., Keith S.J. The costs of schizophrenia. Assessing the burden. Psychiatr Clin North Am 1993, 16:413-423.
    • (1993) Psychiatr Clin North Am , vol.16 , pp. 413-423
    • Rupp, A.1    Keith, S.J.2
  • 4
    • 79956006675 scopus 로고    scopus 로고
    • Cellular and molecular neuropathology of schizophrenia
    • Lippincott Williams & Wilkins, Philadelphia, B.J. Sadock, V.A. Sadock, P. Ruiz (Eds.)
    • Stan A.D., Lesselyong A., Ghose S. Cellular and molecular neuropathology of schizophrenia. Kaplan and Sadock's Comprehensive Textbook of Psychiatry 2009, 1487-1494. Lippincott Williams & Wilkins, Philadelphia. 9th ed. B.J. Sadock, V.A. Sadock, P. Ruiz (Eds.).
    • (2009) Kaplan and Sadock's Comprehensive Textbook of Psychiatry , pp. 1487-1494
    • Stan, A.D.1    Lesselyong, A.2    Ghose, S.3
  • 5
    • 25144456112 scopus 로고    scopus 로고
    • Effectiveness of antipsychotic drugs in patients with schizophrenia
    • Lieberman J.A., Stroup T.S., McEvoy J.P., et al. Effectiveness of antipsychotic drugs in patients with schizophrenia. N Engl J Med 2005, 353:1209-1223.
    • (2005) N Engl J Med , vol.353 , pp. 1209-1223
    • Lieberman, J.A.1    Stroup, T.S.2    McEvoy, J.P.3
  • 6
    • 33749321169 scopus 로고    scopus 로고
    • Randomized controlled trial of the effect on quality of life of second- vs first-generation antipsychotic drugs in schizophrenia. Cost utility of the latest antipsychotic drugs in schizophrenia study (CUtLASS 1)
    • Jones P.B., Barnes T.R.E., Davies L., et al. Randomized controlled trial of the effect on quality of life of second- vs first-generation antipsychotic drugs in schizophrenia. Cost utility of the latest antipsychotic drugs in schizophrenia study (CUtLASS 1). Arch Genl Psychiatry 2006, 63:1079-1087.
    • (2006) Arch Genl Psychiatry , vol.63 , pp. 1079-1087
    • Jones, P.B.1    Barnes, T.R.E.2    Davies, L.3
  • 7
    • 0028927269 scopus 로고
    • 3-[[(Aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles as D2/5-HT2 antagonists with potential atypical antipsychotic activity: antipsychotic profile of iloperidone (HP 873)
    • Strupczewski J.T., Bordeau K.J., Chiang Y., et al. 3-[[(Aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles as D2/5-HT2 antagonists with potential atypical antipsychotic activity: antipsychotic profile of iloperidone (HP 873). J Med Chem 1995, 38:1119-1131.
    • (1995) J Med Chem , vol.38 , pp. 1119-1131
    • Strupczewski, J.T.1    Bordeau, K.J.2    Chiang, Y.3
  • 8
    • 0030426914 scopus 로고    scopus 로고
    • Ex vivo studies with iloperidone (HP 873), a potential atypical antipsychotic with dopamine D2/5-hydroxytryptamine2 receptor antagonist activity
    • Szczepanik A.M., Brougham L.R., Roehr J.E., et al. Ex vivo studies with iloperidone (HP 873), a potential atypical antipsychotic with dopamine D2/5-hydroxytryptamine2 receptor antagonist activity. J Pharmacol Exp Ther 1996, 278:913-920.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 913-920
    • Szczepanik, A.M.1    Brougham, L.R.2    Roehr, J.E.3
  • 9
    • 12644311274 scopus 로고    scopus 로고
    • Iloperidone: preclinical profile and early clinical evaluation
    • Corbett R., Griffiths L., Shipley J.E., et al. Iloperidone: preclinical profile and early clinical evaluation. CNS Drug Rev 1997, 3:120-147.
    • (1997) CNS Drug Rev , vol.3 , pp. 120-147
    • Corbett, R.1    Griffiths, L.2    Shipley, J.E.3
  • 10
    • 0141784133 scopus 로고    scopus 로고
    • Iloperidone
    • Hesselink J.M.K. Iloperidone. IDrugs 2002, 5:84-90.
    • (2002) IDrugs , vol.5 , pp. 84-90
    • Hesselink, J.M.K.1
  • 11
    • 0029050942 scopus 로고
    • The pharmacological profile of iloperidone, a novel atypical antipsychotic agent
    • Szewczak M.R., Corbett R., Rush D.K., et al. The pharmacological profile of iloperidone, a novel atypical antipsychotic agent. J Pharmacol Expl Ther 1995, 274:1404-1413.
    • (1995) J Pharmacol Expl Ther , vol.274 , pp. 1404-1413
    • Szewczak, M.R.1    Corbett, R.2    Rush, D.K.3
  • 12
    • 0030593937 scopus 로고    scopus 로고
    • Iloperidone binding to human and rat dopamine and 5-HT receptors
    • Kongsamut S., Roehr J.E., Cai J., et al. Iloperidone binding to human and rat dopamine and 5-HT receptors. Eur J Pharmacol 1996, 317:417-423.
    • (1996) Eur J Pharmacol , vol.317 , pp. 417-423
    • Kongsamut, S.1    Roehr, J.E.2    Cai, J.3
  • 13
    • 0342980323 scopus 로고    scopus 로고
    • Relationship between dopaminergic and serotonergic neuronal activity in the frontal cortex and the action of typical and atypical antipsychotic drugs
    • Ichikawa J., Meltzer H.Y. Relationship between dopaminergic and serotonergic neuronal activity in the frontal cortex and the action of typical and atypical antipsychotic drugs. Eur Arch Psychiatry Clin Neurosci 1999, 249(Suppl 4):90-98.
    • (1999) Eur Arch Psychiatry Clin Neurosci , vol.249 , Issue.SUPPL 4 , pp. 90-98
    • Ichikawa, J.1    Meltzer, H.Y.2
  • 14
    • 0035673012 scopus 로고    scopus 로고
    • Extended radioligand binding profile of iloperidone: a broad spectrum dopamine/serotonin/norepinephrine receptor antagonist for the management of psychotic disorders
    • Kalkman H.O., Subramanian N., Hoyer D. Extended radioligand binding profile of iloperidone: a broad spectrum dopamine/serotonin/norepinephrine receptor antagonist for the management of psychotic disorders. Neuropsychopharmacology 2001, 25:904-914.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 904-914
    • Kalkman, H.O.1    Subramanian, N.2    Hoyer, D.3
  • 15
    • 0038014053 scopus 로고    scopus 로고
    • H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
    • Kroeze W.K., Hufeisen S.J., Popadak B.A., et al. H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology 2003, 28:519-526.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 519-526
    • Kroeze, W.K.1    Hufeisen, S.J.2    Popadak, B.A.3
  • 16
    • 0018227116 scopus 로고
    • Climbing behaviour induced by apomorphine in mice: a potential model for the detection of neuroleptic activity
    • Costall B., Naylor R.J., Nohria V. Climbing behaviour induced by apomorphine in mice: a potential model for the detection of neuroleptic activity. Eur J Pharmacol 1978, 50:39-50.
    • (1978) Eur J Pharmacol , vol.50 , pp. 39-50
    • Costall, B.1    Naylor, R.J.2    Nohria, V.3
  • 17
    • 33747053349 scopus 로고    scopus 로고
    • Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats
    • Barr A.M., Powell S.B., Markou A., Geyer M.A. Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats. Neuropharmacology 2006, 51:457-465.
    • (2006) Neuropharmacology , vol.51 , pp. 457-465
    • Barr, A.M.1    Powell, S.B.2    Markou, A.3    Geyer, M.A.4
  • 18
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies
    • Braff D.L., Geyer M.A., Swerdlow N.R. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology 2001, 156:234-258.
    • (2001) Psychopharmacology , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 19
    • 0029011364 scopus 로고
    • Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic
    • Sainati S.M., Hubbard J.W., Chi E., et al. Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic. J Clin Pharmacol 1995, 35:713-720.
    • (1995) J Clin Pharmacol , vol.35 , pp. 713-720
    • Sainati, S.M.1    Hubbard, J.W.2    Chi, E.3
  • 21
    • 84988356317 scopus 로고    scopus 로고
    • Vanda Pharmaceuticals, Accessed April 25, 2011
    • Fanapt (iloperidone) tablets Vanda Pharmaceuticals, Accessed April 25, 2011. http://www.fanapt.com.
    • Fanapt (iloperidone) tablets
  • 22
    • 0032160711 scopus 로고    scopus 로고
    • Application of liquid chromatography/mass spectrometry in accelerating the identification of human liver cytochrome P450 isoforms involved in the metabolism of iloperidone
    • Mutlib A.E., Klein J.T. Application of liquid chromatography/mass spectrometry in accelerating the identification of human liver cytochrome P450 isoforms involved in the metabolism of iloperidone. J Pharmacol Expl Ther 1998, 286:1285-1293.
    • (1998) J Pharmacol Expl Ther , vol.286 , pp. 1285-1293
    • Mutlib, A.E.1    Klein, J.T.2
  • 23
    • 0036199878 scopus 로고    scopus 로고
    • Receptor profile of P88-8991 and P95-12113, metabolites of the novel antipsychotic iloperidone
    • Subramanian N., Kalkman H.O. Receptor profile of P88-8991 and P95-12113, metabolites of the novel antipsychotic iloperidone. Prog Neuropsychopharmacol Biol Psychiatry 2002, 26:553-560.
    • (2002) Prog Neuropsychopharmacol Biol Psychiatry , vol.26 , pp. 553-560
    • Subramanian, N.1    Kalkman, H.O.2
  • 24
    • 40849111788 scopus 로고    scopus 로고
    • Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia
    • Cutler A.J., Kalali A.H., Weiden P.J., et al. Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia. J Clin Psychopharmacol 2008, 28(Suppl 1):S20-S28.
    • (2008) J Clin Psychopharmacol , vol.28 , Issue.SUPPL 1
    • Cutler, A.J.1    Kalali, A.H.2    Weiden, P.J.3
  • 25
    • 67649216860 scopus 로고    scopus 로고
    • Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia
    • Volpi S., Potkin S.G., Malhotra A.K., et al. Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia. J Clin Psychiatry 2009, 70:801-809.
    • (2009) J Clin Psychiatry , vol.70 , pp. 801-809
    • Volpi, S.1    Potkin, S.G.2    Malhotra, A.K.3
  • 26
    • 40849110964 scopus 로고    scopus 로고
    • Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial
    • Lavedan C., Volpi S., Polymeropoulos M.H., Wolfgang C.D. Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial. Pharmacogenomics 2008, 9:289-301.
    • (2008) Pharmacogenomics , vol.9 , pp. 289-301
    • Lavedan, C.1    Volpi, S.2    Polymeropoulos, M.H.3    Wolfgang, C.D.4
  • 27
    • 67651174493 scopus 로고    scopus 로고
    • Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study
    • Lavedan C., Licamele L., Volpi S., et al. Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study. Mol Psychiatry 2009, 14:804-819.
    • (2009) Mol Psychiatry , vol.14 , pp. 804-819
    • Lavedan, C.1    Licamele, L.2    Volpi, S.3
  • 28
    • 40849089245 scopus 로고    scopus 로고
    • Efficacy of iloperidone in the treatment of schizophrenia: initial phase 3 studies
    • Potkin S.G., Litman R.E., Torres R., Wolfgang C.D. Efficacy of iloperidone in the treatment of schizophrenia: initial phase 3 studies. J Clin Psychopharmacol 2008, 28(2 Suppl 1):S4-S11.
    • (2008) J Clin Psychopharmacol , vol.28 , Issue.2 SUPPL 1
    • Potkin, S.G.1    Litman, R.E.2    Torres, R.3    Wolfgang, C.D.4
  • 29
    • 40849114977 scopus 로고    scopus 로고
    • Long-term efficacy and safety of iloperidone. Results from 3 clinical trials for the treatment of schizophrenia
    • Kane J.M., Lauriello J., Laska E., et al. Long-term efficacy and safety of iloperidone. Results from 3 clinical trials for the treatment of schizophrenia. J Clin Psychopharmacol 2008, 28(2 Suppl 1):S29-S35.
    • (2008) J Clin Psychopharmacol , vol.28 , Issue.2 SUPPL 1
    • Kane, J.M.1    Lauriello, J.2    Laska, E.3
  • 30
    • 40849102838 scopus 로고    scopus 로고
    • Safety profile of iloperidone: a pooled analysis of 6-week acute-phase pivotal trials
    • Weiden P.J., Cutler A.J., Polymeropoulos M.H., Wolfgang C.D. Safety profile of iloperidone: a pooled analysis of 6-week acute-phase pivotal trials. J Clin Psychopharmacol 2008, 28(2 Suppl 1):S12-S19.
    • (2008) J Clin Psychopharmacol , vol.28 , Issue.2 SUPPL 1
    • Weiden, P.J.1    Cutler, A.J.2    Polymeropoulos, M.H.3    Wolfgang, C.D.4
  • 31
    • 73449115292 scopus 로고    scopus 로고
    • Absence of weight gain association with the HTR2C-759C/T polymorphism in patients with schizophrenia treated with iloperidone
    • Thompson A., Lavedan C., Volpi S. Absence of weight gain association with the HTR2C-759C/T polymorphism in patients with schizophrenia treated with iloperidone. Psychiatry Res 2010, 175:271-273.
    • (2010) Psychiatry Res , vol.175 , pp. 271-273
    • Thompson, A.1    Lavedan, C.2    Volpi, S.3
  • 32
    • 67749095284 scopus 로고    scopus 로고
    • Iloperidone for schizophrenia: a review of the efficacy and safety profile for this newly commercialized second-generation antipsychotic
    • Citrome L. Iloperidone for schizophrenia: a review of the efficacy and safety profile for this newly commercialized second-generation antipsychotic. Int J Clin Pract 2009, 8:1237-1248.
    • (2009) Int J Clin Pract , vol.8 , pp. 1237-1248
    • Citrome, L.1
  • 33
    • 33745691846 scopus 로고    scopus 로고
    • Therapy of hypertension
    • McGraw Hill, New York, L.L. Brunton, J.S. Lazo, K.L. Parker (Eds.)
    • Hoffman B.B. Therapy of hypertension. Goodman & Gilman's The Pharmacological Basis of Therapeutics 2006, 845-868. McGraw Hill, New York. 11th ed. L.L. Brunton, J.S. Lazo, K.L. Parker (Eds.).
    • (2006) Goodman & Gilman's The Pharmacological Basis of Therapeutics , pp. 845-868
    • Hoffman, B.B.1


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