Steric effects on the direct mutagenicity of N-acyloxy-N-alkoxyamides-Probes for drug-DNA interactions

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 722, Issue 1, 2011, Pages 32-38

  Glover, Stephen A ^a   Schumacher, Rhiannon R ^a   Bonin, Antonio M ^a   Fransson, Linda E ^a  

^a UNIVERSITY OF NEW ENGLAND   (Australia)

Author keywords

Ames test; Direct acting; Electrophilic amides; LogP; Mutagenicity; QSAR; Steric effects

Indexed keywords

3,5 DIMETHYLBENZOYL CHLORIDE; AMIDE; MUTAGENIC AGENT; N ACETOXY N BUTOXY 3,5 DIMETHYLBENZAMIDE; N ACYLOXY N ALKOXYAMIDE; N BUTOXY 3,5 DIMETHYLBENZAMIDE; N BUTOXY N CHLORO 3,5 DIMETHYLBENZAMIDE; N BUTOXY N(2,6 DIMETHYLBENZOYLOXY)BENZAMIDE; N BUTOXY N(3,5 DIMETHYLBENZOYLOXY)BENZAMIDE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DNA PROBE; DRUG ACTIVITY; DRUG DNA INTERACTION; DRUG STRUCTURE; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SALMONELLA TYPHIMURIUM; STEREOSPECIFICITY; SYNTHESIS;

ALCOHOLS; AMIDES; DNA DAMAGE; MUTAGENICITY TESTS; MUTAGENS; SALMONELLA TYPHIMURIUM; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); SALMONELLA TYPHIMURIUM;

EID: 79956038423     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.02.007     Document Type: Article

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