Death due to acute salicylate intoxication despite dialysis

Journal of Emergency Medicine

Volumn 40, Issue 5, 2011, Pages 515-517

  Minns, Alicia B ^a   Cantrell, F Lee ^a   Clark, Richard F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

acidosis; antidote; charcoal; renal dialysis; salicylate; toxicity

Indexed keywords

ACETYLSALICYLIC ACID; ACTIVATED CARBON; BICARBONATE; CHLORIDE; CREATININE; GLUCOSE; INFUSION FLUID; POTASSIUM; POTASSIUM CHLORIDE; SODIUM;

ACUTE TOXICITY; ADULT; AGITATION; ARTERIAL GAS; ARTICLE; AUTOPSY; CASE REPORT; CONFUSION; CREATININE BLOOD LEVEL; DEATH; DIAPHORESIS; DRUG INTOXICATION; EMERGENCY CARE; EMERGENCY WARD; HEMODIALYSIS; HUMAN; LUNG EDEMA; MALE; OXYGEN SATURATION; PRIORITY JOURNAL; SINGLE DRUG DOSE; UREA NITROGEN BLOOD LEVEL;

ADULT; CHARCOAL; FATAL OUTCOME; HUMANS; MALE; POISONING; RENAL DIALYSIS; SALICYLIC ACID; SODIUM BICARBONATE; SUICIDE;

EID: 79956029766     PISSN: 07364679     EISSN: 07364679     Source Type: Journal    
DOI: 10.1016/j.jemermed.2010.02.015     Document Type: Article

References (15)

1. Chan TYK. The risk of severe salicylate poisoning following the ingestion of topical medicaments or aspirin. Postgrad Med J 1996;72:109-12. (Pubitemid 26048231)
2. th annual report. Clin Toxicol (Phila) 2008;46:927-1057.
3. Wrathall G, Sinclair R, Moore A, Pogson D. Three case reports of the use of haemodiafiltration in the treatment of salicylate overdose. Hum Exp Toxicol 2001;20:491-5. (Pubitemid 34030756)
4. Cohen DL, Post J, Ferroggiaro AA, Perrone J, Foster MH. Chronic salicylism resulting in noncardiogenic pulmonary edema requiring hemodialysis. Am J Kidney Dis 2000;36:1-4.
5. Fertel BS, Nelson LS, Goldfarb DS. The underutilization of hemodialysis in patients with salicylate poisoning. Kidney Int 2009;75:1349-53.
6. O'Malley GF. Emergency department management of the salicylate-poisoned patient. Emerg Med Clin North Am 2007;25:333-46. (Pubitemid 46669881)
7. McGuigan MA. A two-year review of salicylate deaths in Ontario. Arch Intern Med 1987;147:510-2. (Pubitemid 17036592)
8. Dillon EC Jr, Wilton JH, Barlow JC, Watson WA. Large surface area activated charcoal and the inhibition of aspirin absorption. Ann Emerg Med 1989;18:547-52. (Pubitemid 19127695)
9. Stolback AI, Hoffman RS, Nelson LS. Mechanical ventilation was associated with academia in a case series of salicylate-poisoned patients. Acad Emerg Med 2008;15:866-9.
10. Vree TB, Van Ewijk-Beneken Kolmer EM, Verwey-Van Wissen CP, Hekster YA. Effect of urinary pH on the pharmacokinetics of salicylic acid, with its glycine and glucuronide conjugates in human. Int J Clin Pharmacol Ther 1994;32:550-8. (Pubitemid 24301202)
11. Prescott LF, Balali-Mood M, Critchley JA, Johnstone AF, Proudfoot AT. Diuresis or urinary alkalinisation for salicylate poisoning? Br Med J (Clin Res Ed) 1982;285:1383-6.
12. Proudfoot AT, Krenzelok EP, Vale JA. Position paper on urine alkalinization. J Toxicol Clin Toxicol 2004;42:1-26. (Pubitemid 38450934)
13. Winchester JF, Gelfand MC, Helliwell M, Vale JA, Goulding R, Schreiner GE. Extracorporeal treatment of salicylate or acetaminophen poisoning - is there a role? Arch Intern Med 1981;141:370-4.
14. Schreiner GE, Berman LB, Griffin J, Feys J. Specific therapy for salicylism. N Engl J Med 1955;253:213-17.
15. Jacobsen D, Wiik-Larsen E, Bredesen JE. Haemodialysis or haemoperfusion in severe salicylate poisoning? Hum Toxicol 1988;7:161-3.