Hepatic protective effect and single-dose toxicity study of water extract of Cordyceps militaris grown upon Protaetia dreujtarsis

Korean Journal of Food Science and Technology

Volumn 40, Issue 1, 2008, Pages 106-110

  Jo, Wol Soon ^a   Nam, Byung Hyouk ^a   Oh, Su Jung ^a   Choi, Yoo Jin ^a   Kang, Eun Young ^a   Hong, Sook Hee ^b   Lee, Sang Ho ^b   Jeong, Min Ho ^a  

^a Dong A University   (South Korea)

^b Seogwipo Agricultral Technique Center   (South Korea)

Author keywords

CCl4; Cordyceps militaris; Hepatoprotection; Liver; Protaetia dreujtarsis; Toxicity

Indexed keywords

CORDYCEPS; CORDYCEPS MILITARIS; PROTAETIA; RATTUS;

EID: 79956016582     PISSN: 03676293     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Lieber CS. Alcohol and the liver. Gastroenterology 106: 1085-1105 (1994)
2. Lee KW, Nam BH, Jo WS, Oh SJ, Kang EY, Choi YJ, Lee JY, Cheon SC, Jeong MH, Lee JD. Collection, classification, and hepatic effect of native Cordyceps militaris. Korean J. Mycol. 34: 7-13 (2006)
3. Brown BR, Sipes I, Sagalyn G, Ann M. Mechanisms of acute hepatic toxicity. Anesthesiology 41: 554-561 (1974)
4. Goodman GA. Carbon Tetrachloride in the Pharmacological Basis of Therapeutics. Macmillan Publishing Co., New York, NY, USA. pp. 1635-1636 (1985)
5. Ilett KF, Reid WD, Sipes IQ Krishna G Chloroform toxicity in mice: Correlation renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules. Exp. Mol. Pathol. 19: 205-215 (1973)
6. Shim JY, Lee YS, Lim SS, Shin KH, Hyun JE, Kim SY, Lee EB. Pharmacological activities of Paecilomyces japonica, a new type Cordyceps sp. Korean. J. Pharmacogn. 31: 163-167 (2000)
7. Recknagel RO. Carbon tetrachloride hepatotoxicity Pharmacol. Rev. 19: 145-208 (1967)
8. Rechnagel RO, Glende EA. Carbon tetrachloride hepatotoxicity: An example of lethal cleavage. Crit. Rev. Toxicol. 2: 263-297 (1973)
9. Villarruel MC, Diaz Gomez MI, Castro JA. The nature of the in vitro irreversible binding of carbon tetrachloride to microsomal lipids. Toxicol. Appl. Pharm. 33: 106-114 (1975)
10. Glende EA, Pushpendran CK. Activation of phospholipase A2 by carbon tetrachloride in isolated rat hepatocytes. Biochem. Pharmacol. 35: 3301-3307 (1986) (Pubitemid 16001438)
11. 4 and release of a sequestered calcium pool. Biochem. Pharmacol. 35: 4131-4137 (1986) (Pubitemid 17204079)
12. Plaa GL, Hewitt WR. Toxicology of the Liver. Raven Press, New York, NY, USA. pp. 103-120 (1982)
13. Rechnagel RO. A new direction in the study of carbon tetrachloride hepatotoxicity. Life Sci. 33: 401-408 (1983)
14. Hassan HM. Biosynthesis and regulation of superoxide dismutases. Free Radical Bio. Med. 5: 377-385 (1988)
15. Byers T, Perry G Dietary carotenes, vitamin C, and vitamin E as protective antioxidants in human cancers. Ann. Rev. Nutr. 12: 135-159 (1992)
16. Nevin KG Vijayammal PL. Effect of Aerva lanata against hepatotoxicity of carbon tetrachloride in rats. Environ. Toxicol. Phar. 20: 471-477 (2005) (Pubitemid 41318061)
17. Poli G Gravela E, Albano E, Dianzani MU. Studies on fatty liver with isolated hepatocytes: The action of carbon tetrachloride on lipid peroxidation, protein and triglyceride synthesis and secretion. Exp. Mol. Pathol. 30: 116-127 (1979). (Pubitemid 9121708)
18. Seakins A, Robinson DS. The effect of the administration of carbon tetrachloride on the formation of plasma lipoproteins in the rat. Biochemistry 86: 401-407 (1963)
19. Kim MN, Oh SW, Lee DS, Ham, SS. Antioxidative and antimutagenic effect of the ethanol extract from Cordyceps militaris. Korean J. Postharv. Sci. Technol. 8: 109-117 (2001)
20. Koh JB, Choi MA. Effect of Cordyceps militaris on lipid metabolism in rats fed cholesterol diet. J. Food Sci. Nutr. 34: 265-270 (2001)
21. Plaa GL. Toxic response of the liver, pp. 334-353. In: Casarett and Doull's Toxicology. Amdur MO, Doull J, Klassen CD (eds). Pergamon Press, New York, NY, USA. (1991)
22. Hayes AW. Principles and Methods of Toxicology. Raven Press, New York, NY, USA. pp. 407-413 (1982)
23. Teocharis SE, Margelo AP, Skaltsas SD, Spiliopoulou CA, Koutselinis AS. Induction of metallothionein in the liver of carbon tetrachloride intoxicated rats: An immuno histochemical study. Toxicology 161: 129-138 (2001) (Pubitemid 32273168)