Psychosocial dwarfism: Psychopathological aspects and putative neuroendocrine markers

Psychiatry Research

Volumn 188, Issue 1, 2011, Pages 96-101

  Muñoz Hoyos, Antonio ^a   Molina Carballo, Antonio ^a   Augustin Morales, MaríadelCarmen ^a   Contreras Chova, Francisco ^a   Naranjo Gómez, Ana ^a   Justicia Martínez, Fuensanta ^a   Uberos, José ^a  

^a HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

Author keywords

endorphins; ACTH; Affective deprivation syndrome; Children; Melatonin; Non organic failure to thrive; Psychosocial dwarfism; Serotonin; Tryptophan

Indexed keywords

BETA ENDORPHIN; CORTICOTROPIN; KYNURENINE; MELATONIN; SEROTONIN; TRYPTOPHAN;

ADOLESCENT; AFFECTIVE DEPRIVATION SYNDROME; AMINO ACID METABOLISM; ARTICLE; BLOOD SAMPLING; CHILD; CHRONIC STRESS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; FAILURE TO THRIVE; FEMALE; HORMONE BLOOD LEVEL; HUMAN; MALE; MOOD DISORDER; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN MODIFICATION; SCHOOL CHILD; SIGNAL TRANSDUCTION; SOCIAL ISOLATION;

ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ANALYSIS OF VARIANCE; BETA-ENDORPHIN; CHI-SQUARE DISTRIBUTION; CHILD; CHILD BEHAVIOR DISORDERS; CHILD, PRESCHOOL; CIRCADIAN RHYTHM; DEVELOPMENTAL DISABILITIES; FAILURE TO THRIVE; FEMALE; HUMANS; KYNURENINE; MALE; MELATONIN; NEUROSECRETORY SYSTEMS; PSYCHOPATHOLOGY; SEROTONIN;

EID: 79956009012     PISSN: 01651781     EISSN: 01651781     Source Type: Journal    
DOI: 10.1016/j.psychres.2010.10.004     Document Type: Article

References (46)

1. Acuña-Castroviejo D., Escames G., Macías M., Muñoz-Hoyos A., Molina-Carballo A., Arauzo M., Montes R., Vives F. Cell protective role of melatonin in the brain. Journal of Pineal Research 1995, 19:57-63.
2. Blizzard R.M., Bulatovic A. Psychosocial short stature: a syndrome with many variables. Baillière's Clinical Endocrinology and Metabolism 1992, 6:687-712.
3. Bowlby J. Maternal Care and Mental Health 1952, World Health Organization, Geneva.
4. Bowlby J. Separation: Anxiety and Anger. Attachment and Loss 1973, 409-429. Basic Books, New York.
5. Bruce J., Fisher P.A., Pears K.C., Levine S. Morning cortisol levels in preschool-aged foster children: differential effects of maltreatment type. Developmental Psychobiology 2009, 51:14-23.
6. Casler L. Maternal deprivation: a critical review of the literature. Monograph of the Society for Research in Child Development 1961, 26:1-64.
7. Chmurzynska A. Fetal programming: link between early nutrition, DNA methylation, and complex diseases. Nutrition Reviews 2010, 68:87-98.
8. Contreras Alemán, G., 1997. Contribución al conocimiento patogénico del retraso de crecimiento de causa no orgánica. Universidad de Granada, Doctoral thesis.
9. Coppini D., Benassi C., Montorsi M. Cuantitative determination of tryptophan metabolites in biological fluids. Clinical Chemistry 1959, 5:391-394.
10. de Kerdanet M., Severo T., Lecomu M. Retard de croissance d'origine psichosociale. Aspects cliniques et biologiques de quatre observations. Pédiatrie 1993, 48:783-787.
11. Ehrlich S., Salbach-Andrae H., Eckart S., Merle J.V., Burghardt R., Pfeiffer E., Franke L., Uebelhack R., Lehmkuhl U., Hellweg R. Serum brain-derived neurotrophic factor and peripheral indicators of the serotonin system in underweight and weight-recovered adolescent girls and women with anorexia nervosa. Journal of Psychiatry & Neuroscience 2009, 34:323-329.
12. Fries A.B., Shirtcliff E.A., Pollak S.D. Neuroendocrine dysregulation following early social deprivation in children. Developmental Psychobiology 2008, 50:588-599.
13. Gilmour J., Skuse D. A case-comparison study of the characteristics of children with a short stature syndrome induced by stress (Hyperphagic short stature) and a consecutive series of unaffected "stressed" children. Journal of Child Psychology and Psychiatry 1999, 40:969-978.
14. Kertes D.A., Gunnar M.R., Madsen N.J., Long J.D. Early deprivation and home basal cortisol levels: a study of internationally adopted children. Developmental Psychopathology 2008, 20:473-491.
15. Leyton M., Young S.N., Pihl R.O., Etezadi S., Lauze C., Blier P., Baker G.B., Benkelfat C. A comparison of the effects of acute tryptophan depletion and acute phenylalanine/tyrosine depletion in healthy women. Advances in Experimental Medicine and Biology 1999, 467:67-71.
16. Maestroni G.J.M., Conti A. Anti-stress role of the melatonin-immuno-opioid network: Evidence for a physiological mechanism involving T cell-derived, immunoreactive β-endorphin and met-enkephalin binding to thymic opioid receptors. The International Journal of Neuroscience 1991, 61:289-298.
17. Markus C.R., Olivier B., Panhuysen G.E., Van Der G.J., Alles M.S., Tuiten A., Westenberg H.G., Fekkes D., Koppeschaar H.F., de Haan E.E. The bovine protein alpha-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress. The American Journal of Clinical Nutrition 2000, 71:1536-1544.
18. Markus R., Panhuysen G., Tuiten A., Koppeschaar H. Effects of food on cortisol and mood in vulnerable subjects under controllable and uncontrollable stress. Physiology & Behaviour 2000, 70:333-342.
19. Masse N.P. Introducción a la Pediatría Social. Pediatría Social 1978, Labor, Barcelona. R. Mande, N. Masse, M. Manciaux (Eds.).
20. Molina-Carballo A., Muñoz-Hoyos A., Rodríguez-Cabezas T., Acuña-Castroviejo D. Day-night variations in melatonin secretion by pineal gland during febrile and epileptic convulsions in children. Psychiatry Research 1994, 52:273-283.
21. Molina-Font J.A., Muñoz-Hoyos A. Retraso del crecimiento no orgánico o psicosocial. Niños maltratados 1998, 145-159. Comares, Granada. J. Casado Flores, J.A. Díaz Huertas, C. Martínez González (Eds.).
22. Money J. The Kaspar Hauser Syndrome of "Psychosocial Dwarfism": Deficient Statural, Intellectual, and Social Growth Induced by Child Abuse 1992, Prometheus Books, New York.
23. Moreno-Madrid F., Muñoz-Hoyos A., Sánchez-Forte M., Molina-Carballo A., Macías M., Escames G., Narbona-López E., Acuña-Castroviejo D. Valoración de un test de función pineal con l-triptófano en niños. Investigación Clínica 1999, 2:297-303.
24. Muñoz-Hoyos A., Amorós Rodríguez I., Molina-Carballo A., Uberos-Fernández J., Acuña-Castroviejo D. Pineal response after pyridoxine test in children. Journal of Neural Transmission 1996, 103:833-842.
25. Muñoz-Hoyos A., Augustin-Morales M.C., Ruiz-Cosano C., Molina-Carballo A., Fernández-García J.M., Galdó-Muñoz G. Institutional childcare and the affective deficiency syndrome: consequences on growth, nutrition and development. Early Human Development 2001, 65:S145-S152.
26. Muñoz-Hoyos A., Bonillo-Perales A., Avila-Villegas R., González-Ripoll Garzón M., Uberos-Fernández J., Florido-Navío J., Molina-Carballo A. Levels of melatonin in the first week of life: its relationship with the antioxidant response in the perinatal period. Neonatology 2007, 92:209-216.
27. Muñoz-Hoyos A., Molina-Carballo A., Uberos J., Contreras-Chova F., Augustin-Morales M.C., Ruiz-Alba Gómez M., Galdó-Muñoz G. Serum melatonin concentration in the child with non-organic failure to thrive: comparison with others types of stress. Journal of Biological Regulators and Homeostatic Agents 2009, 23:15-22.
28. Muñoz-Hoyos A., Molina-Carballo A., Macías M., Rodríguez-Cabezas T., Martín-Medina E., Narbona-López E., Uberos-Fernández J., Valenzuela-Ruiz A., Molina-Font J.A. Comparison between tryptophan methoxyindole and kynurenine metabolic pathways in normal and preterm neonates and in neonates with acute fetal distress. European Journal of Endocrinology 1998, 139:89-95.
29. Mussen P.H., Conger J.J., Kagan J. Child Development and Personality 1979, Harper & Row, New York.
30. Narbona-López E., Bayés R., Robles C., Muñoz-Hoyos A., Galdó G., Núñez J. Alteraciones persistentes en la excreción urinaria de metabolitos del triptófano en niños con asfixia intraparto y anomalías posteriores del desarrollo psiconeurológico. Laboratorio 1986, 81:321-337.
31. Patton R.G., Gardner L.I. Influence of family environment on growth: the syndrome of "maternal deprivation". Pediatrics 1962, 30:957-962.
32. Powell G.F. Nonorganic failure to thrive in infancy: an update on nutrition, behavior, and growth. Journal of the American College of Nutrition 1988, 7:345-353.
33. Rutter M., Beckett C., Castle J., Colvert E., Kreppner J., Mehta M., Stevens S., Sonuga-Barke E. Effects of profound early institutional deprivation: an overview of findings from a UK longitudinal study of Romanian adoptees. European Journal of Developmental Psychology 2007, 4:332-350.
34. Seisdedos N. STAIC, Cuestionario de Autoevaluación 1990, TEA Ediciones S.A, Madrid.
35. Shaoul R., Kessel A., Toubi E., Lanir A., Glazer O., Jaffe M. Leptin and cytokines levels in children with failure to thrive. Journal of Pediatric Gastroenterology and Nutrition 2003, 37:487-491.
36. Silver H.K., Finkelstein M. Deprivation dwarfism. The Journal of Pediatrics 1967, 70:317-324.
37. Skuse D., Albanese A., Stanhope R., Gilmour J., Voss L. A new stress-related syndrome of growth failure and hyperphagia in children, associated with reversibility of growth-hormone insufficiency. Lancet 1996, 348:353-358.
38. Sonuga-Barke E.J., Beckett C., Kreppner J., Castle J., Colvert E., Stevens S., Hawkins A., Rutter M. Is sub-nutrition necessary for a poor outcome following early institutional deprivation?. Developmental Medicine and Child Neurology 2008, 50:664-671.
39. Tarren-Sweeney M. Patterns of aberrant eating among pre-adolescent children in foster care. Journal of Abnormal Child Psychology 2006, 34:621-632.
40. Tisher M., Lang M. Children's Depression Scale: Research Edition 1978, The Australian Council for Educational Research, Melbourne, [Spanish translation: Cuestionario de Depresión para Niños. Madrid: TEA, 1983].
41. van Oers H.J., de Kloet E.R., Levine S. Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic responses to stress. Brain Research. Developmental Brain Research 1998, 111:245-252.
42. Vazquez D.M., Lopez J.F., Van Hoers H., Watson S.J., Levine S. Maternal deprivation regulates serotonin 1A and 2A receptors in the infant rat. Brain Research 2000, 855:76-82.
43. Voss L.D., Mulligan J., Betts P.R. Short stature at school entry-an index of social deprivation? (The Wessex Growth Study). Child: Care, Health and Development 1998, 24:145-156.
44. Wahlund B. Melatonin in psychiatric disorders - subtyping affective disorder. Biological Signals and Receptors 1999, 8:120-125.
45. Weterberg L. Melatonin and affective disorders. Photoperidism: Melatonin and the Pineal 1985, 253-265. Evered, London. S. Clark (Ed.).
46. Wilcox W.D., Nieburg P., Miller D.S. Failure to thrive. A continuing problem of definition. Clinical Pediatrics (Philadelphia) 1989, 28:391-394.